Reference

1. Koran, L. M.: The reliability of clinical methods, data and judgments. N Engl J Med 293: 642-646, 695-701 (1975).
2. Cay, E. L., et al.: Patient's assessment of the result of surgery for peptic ulcer. Lancet 1: 29-31 (1975).
3. Kulkarni S. K., Hand Book of Experimental Pharmacology, 3rd ed, Vallabh Prakashan New Delhi, 2004, 21.
4. http://www.temple.edu/pascope/about_trials.htm
5. Clinical trial Wikipedia, the free encyclopedia .Available from: URL http://en.wikipedia.org/ wiki/clinical-trial.
6. ICH Harmonized Tripartite Guideline for Good Clinical Practice ‘Academy For Clinical Excellence’.
7. Maxwell C, Domenet JG, Joyce CRR.1971. Instant experience in clinical trials:a novel aid to teaching by simulation. J.Clin. Pharmacol. 11(5):323–31
8. Marsh BT. 1975. The planning of a clini-cal trials workshop. Br. J. Clin. Phar-macol. 2(5):455–61
9. Madsen BW, Woodings TL, Ilett KF,Shenfield GM, Potter JM, et al. 1978.Clinical trial experience by simulation: aworkshop report. Br. Med. J. 2(6148):1333–35
10.  Bland JM. 1986. Computer simulation ofclinical trial as an aid to teaching the concept of statistical significance. Stat. Med.5:193–97
11. Pocock SJ, Simon R. 1975. Sequentialtreatment assignment with balancing forprognostic factors in the controlled clinical trial. Biometrics 31(1):103–15
12.  Jones DR. 1979. Computer simulation asa tool for clinical trial design. Int. J. BioMed. Comp. 10:145–50
13. DeMets DL. 1981. Practical aspects ofdecision making in clinical trials: the coronary drug project as a case study. Control Clin. Trials 1(4):363–76
14. Lee KL, Frederick M, Starmer CF, HarrisPJ, Rosati RA. 1980. Clinical judgementand statistics: lessons from a simulatedrandomized trial in coronary artery disease. Circulation 61(3):508–15
15. Hippocrates. (Various works from the Hippocratic Corpus)
16. Laennec, R.T.H. (1819). "De l’Auscultation Médiate."
17. Osler, W. (1892). "The Principles and Practice of Medicine."
18. Sackett, D.L. et al. (2000). "Evidence-Based Medicine: How to Practice and Teach EBM."
19. Various studies and research publications on diagnostic accuracy and clinical method evaluation in medical journals (e.g., New England Journal of Medicine, JAMA, The Lancet).
20. The Lancet (2009). "Phase 0 trials: A platform for drug development?". The Lancet. 374 (9685): 176–118
21. Yang, Z. J., et al. (2010). "Motivation for Health Information Seeking and Processing About Clinical Trial Enrollment." Health Communication 25(5): 423-436.
22. Life Sciences Strategy Group, (May 2009) "Clinical Trial Technology Utilization, Purchasing Preferences & Growth Outlook" Syndicated Publication.
23. "India: Prime Destination for Unethical Clinical Trials". Common Dreams.
24. Paul J, Seib R, Prescott T (Mar 2005). "The Internet and Clinical Trials: Background, Online Resources, Examples and Issues" (Free full  text).Journal of medical Internet research. 7 (1): e5.
25. ICH Guideline for Good Clinical Practice: Consolidated Guidance
26. Ginsberg HN, Kris-Etherton P, Dennis B, Elmer PJ, Ershow A, Lefevre M, Pearson T, Roheim P, Ramakrishnan R, Reed R Effects of reducing dietary saturated fatty acids on plasma lipids and lipoproteins in healthy subjects: the DELTA study, protocol 1 Arterioscler Thromb Vasc Biol, 18 (3) (1998), pp. 441-449
27. Berglund L, Lefevre M, Ginsberg HN, Kris-Etherton PM, Elmer PJ, Stewart PW, Ershow A, Pearson TA, Dennis BH, Roheim PS Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial states.
28. Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Vogt TM, Cutler JA, Windhauser MM A clinical trial of the effects of dietary patterns on blood pressure
29. Appel LJ, Sacks FM, Carey VJ, Obarzanek E, Swain JF, Miller ER, Conlin PR, Erlinger TP, Rosner BA, Laranjo NM Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the OmniHeart randomized trial
30. Sacks FM, Carey VJ, Anderson CA, Miller ER, Copeland T, Charleston J, Harshfield BJ, Laranjo N, McCarron P, Swain J Effects of high vs low glycemic index of dietary carbohydrate on cardiovascular disease risk factors and insulin sensitivity: the OmniCarb randomized clinical trial
31. Howard BV, Van Horn L, Hsia J, Manson JE, Stefanick ML, Wassertheil-Smoller S, Kuller LH, LaCroix AZ, Langer RD, Lasser NL Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
32. Appel LJ., Champagne CM, Harsha DW, Cooper LS, Obarzanek E, Elmer PJ, Stevens VJ, Vollmer WM, Lin PH, Svetkey LP Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial
33. Altman DG, Bland JM. How to randomise. BMJ. 1999; 319: 703-704.
34. Altman DG, Bland JM. How to randomise. BMJ. 1999; 319: 703-704.
35. Altman DG, Bland JM. How to randomise. BMJ. 1999; 319: 703-704.
36. Suresh K. An overview of randomization techniques: An unbiased assessment of outcome in clinical research. J Hum Reprod Sci. 2011; 4: 8-11
37.  Karanicolas PJ, Farrokhyar F, Bhandari M. Practical tips for surgical research: Bling: Who, what, when, why, how? Can J Surg. 2010; 53: 345-348.
38. [Karanicolas PJ, Farrokhyar F, Bhandari M. Practical tips for surgical research: Blinding: Who, what, when, why, how? Can J Surg. 2010; 53: 345-348.]
39. Lim HJ, Hoffmann RG. Study design: The basics. Methods Mol Biol. 2007; 404: 1-17
40. Neutel JM and Smith DHG. Evaluation of angiotensin II receptor blockers for 24-hour blood pressure control: meta-analysis of a clinical database. J Clin Hypertens. 2003; 5(1): 58-63.
41. Wan M., Orlu-Gul M., Legay H., Tuleu C. Blinding in pharmacological trials: The devil is in the details. Arch. Dis. Child. 2013;98:656—659. doi: 10.1136/archdischild-2013-304037.
42. Blader J.C. Can keeping clinical trial participants blind to their study treatment adversely affect subsequent care? Contemp. Clin. Trials. 2005;26:290—299. doi: 10.1016/j.cct.2005.01.003.
43. Concato J, Shah N, Horwitz RI. Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med. 2000;342(25):1887-1892.
44. Grimes DA, Schulz KF. An overview of clinical research: the lay of the land. Lancet. 2002;359(9300):57-61.