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Abstract

Bitter melon is a tropical vine found in India, China, and Southeast Asia. It contains 60 phyto-medicines that treat many diseases. Bitter melon has many bioactive components that are beneficial for medicinal use. Bitter melon is also used in obesity. Bitter melon has very few side effects and has more beneficial properties. Whole parts of bitter melon have medicinal properties. Bitter melon is used to treat diabetes, cancer, and viral diseases. In this, we study the many functions of bitter melon as well as their function according to their activity.

Keywords

Bitter melon, Momocardica Charantia, Bioactive compounds, Nutrients

Reference

  1. Cefalu WT, Ye J, Wang ZQ. Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans. Endocr Metab Immune Disord Drug Targets. 2008;8:78–81.
  2. Cousens G. There is a cure for diabetes: the tree of life 21 day program. California: North Atlantic Books; 2008. pp. 191–192.
  3. Wang S, Li Z, Yang G, Ho CT, Li S. Momordica charantia: a popular health-promoting vegetable with multifunctionality. Food Funct. 2017; 8(5):1749-1762. DOI: 10.1039/c6fo01812b
  4. .Kole, C., Matsumura, H., & Behera, T. K. (Eds.) (2020). The bitter gourd genome. Cham, Switzerland: Springer.
  5. Sorifa, A. M. (2018). Nutritional compositions, health promoting phytochemicals and value added products of bitter gourd: A review. International Food Research Journal, 25(5), 1763–1772.
  6. Phytochemical Test of Bitter Melon (Momordica charantia L) Herb and its Effect on Rat Blood Sugar Levels,Ijazati Alfitroh1; Suhatri1; Harrizul Rivai1*International Journal of Pharmaceutical Sciences and Medicine (IJPSM),Vol.6 Issue. 7, July- 2021, pg. 153-163
  7. Recent Advances in Momordica charantia: Functional Components and Biological ActivitiesShuo Jia, Mingyue Shen, Fan Zhang, and Jianhua Xie*Int J Mol Sci. 2017 Dec; 18(12): 2555. Published online 2017 Nov 28. doi: 10.3390/ijms18122555
  8.  Yuwai KE, Sundar Rao K, Kaluwin C, Jones GP, Rivett DE. Chemical composition of Momordica charantia L. fruits. J Agric Food Chem. 1991;39:1762–1763. doi: 10.1021/jf00010a013.
  9. https://www.webmd.com/vitamins/ai/ingredientmono-795/bitter-melon
  10. Weng JR; Bai LY; Chiu CF; Hu JL; Chiu SJ; Wu CY Cucurbitane triterpenoid from Momordica charantia induces apoptosis and autophagy in breast cancer cells, in part, through peroxisome proliferator-activated receptor gamma activation. Evid. Based Complement Alternat. Med, 2013, 2013, 935675.
  11.  Zhang CZ; Fang EF; Zhang HT; Liu LL; Yun JP Momordica charantia lectin exhibits antitumor activity towards hepatocellular carcinoma. Invest New Drugs, 2015, 33, 1–11.
  12. Effect of Bitter Melon Extracts on Lipid Levels in Japanese Subjects: A Randomized Controlled Study Hiroki Kinoshita 1 , 2 and Yasuyuki Ogata 2Evid Based Complement Alternat Med. ; 2018: 4915784. Published online 2018 Nov 8. doi: 10.1155/2018/4915784
  13. Bitter Melon and Diabetes Medically reviewed by Lisa Hodgson, RDN, CDN, CDCES, FADCES, Nutrition — By Natalie Silver — Updated on February 24, 2021
  14. Tan ES Abdullah A Maskat MY Effect of drying methods on total antioxidant capacity of bitter gourd (Momordica charantia) fruit. AIP Conference Proceedings. 2013;1571:710–716.
  15. High cholesterol: Overview Created: August 14, 2013; Last Update: September 7, 2017; Next update: 2020.
  16. Goo KS Ashari S Basuki N Sugiharto AN The bitter gourd Momordica charantia L.: morphological aspects, charantin and vitamin C contents. IOSR-Journal of Agriculture and Veterinary Science. 2016;9:76–81
  17. https://www.sciencedirect.com/science/article/abs/pii/B9780323857307000175#:~:text=Bitter melon phytochemicals possess antiviral,efficacy on managing infectious diseases.
  18. Benefits of Bitter Melon (Bitter Gourd) and Its Extract Medically reviewed by Sade Meeks, MS, RD, Nutrition — By Rachael Ajmera, MS, RD — Updated on April 6, 2023
  19. https://pharmeasy.in/blog/ayurveda-uses-benefits-side-effects-of-karela-bitter-gourd/#20.
  20. Chen Q., Li E. T. S. Reduced adiposity in bitter melon (Momordica charantia) fed rats is associated with lower tissue triglyceride and higher plasma catecholamine. British Journal of Nutrition. 2005;93(5):747–754. Doi: 10.1079/bjn20051388.
  21. Cytogenetics of two Indian varieties of Momordica charantia L. (bittergourd) by Ipshita Ghosha, Biplab Kumar Bhowmickab, Sumita Jha. Center of Advanced study, Department of Botany, University of Calcutta. 11 June 2018. Retrieved 8 January 2022

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Arti Prakash Aher
Corresponding author

Nandkumar Shinde college of pharmacy

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A.D.Khajekar
Co-author

Nandkumar Shinde college of pharmacy

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A.K Hatkar
Co-author

Nandkumar Shinde college of pharmacy

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R.M.Kawade
Co-author

Nandkumar Shinde college of pharmacy

A. P. Aher*, A. D. Khajekar, A. K. Hatkar, R. M. Kawade, Comprehensive review on Bitter melon, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 121-124. https://doi.org/10.5281/zenodo.10276883

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