Synthesis And Antimitotic Activity of Benzotriazole Compound

Abstract

The present work to Synthesize benzotriazole Nucleus and study the biological activity of Antimitotic method through by seed germination assay by using the green gram seeds. It is preliminary screening method to identify this benzotriazole basic nucleus is having Anticancer property. By using this seed germination assay method be can studied that this nucleus is having inhibition of seed germination Activity.

Keywords

Introduction

Table.1: Chemical Information of Benzotriazole [1-3]

Table.2: Materials used for the Reaction

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Table.3: Procedure for the Preparation of the Reaction mixture:

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            <img alt="BZT Drug Solution.png" height="150" src="https://www.ijpsjournal.com/uploads/createUrl/createUrl-20250424120805-2.png" width="150">
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Figure.1: BZT Drug Solution             

Figure.2: Green Gram Seeds

Table.5: Preparation of Antimitotic activity of Benzotriazole (BZT) compound.

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            <img alt="Results of Antimitotic Assay method for Benzotriazole Drug solution.png" height="150" src="https://www.ijpsjournal.com/uploads/createUrl/createUrl-20250424120805-1.png" width="150">
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Figure.3: Results of Antimitotic Assay method for Benzotriazole Drug solution

Table.6: Result of Antimitotic Activity of Benzotriazole compound.

From the Figure.3 We obtained the results of antimitotic activity from this we calculated the average length of seeds germination from each and every individual concentrations of Benzotriazole (BZT) drug solution.Then after we plot a graph for taking the Average length of seeds in Y-xis and concentration of Benzotriazole drug solution in X-Axis.

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            <img alt="Graphical Representation of Antimitotic Assay of Benzotriazole Drug Solution.png" height="150" src="https://www.ijpsjournal.com/uploads/createUrl/createUrl-20250424120805-0.png" width="150">
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Figure.4: Graphical Representation of Antimitotic Assay of Benzotriazole Drug Solution

CONCLUSION:

From the Above results of Antimitotic activity of Benzotriazole (BZT) Drug solution we observe that there is a gradually reduction in Average length of the seeds.so we conclude that highest strength of the BZT drug solution is hot having any seed germination from this it is conformed that the Benzotriazole Compound is having Antimitotic activity.

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