Phytopharmaceutical Development of a Pain-Relieving Herbal Roll-On

Herbal roll-ons are the natural liquid preparation containing volatile oils used to relieve pain and stress.

Tulsi-Tulsi has a scared and highly valued herb in Hinduism and ayurveda. Tulsi has a wide range of traditional uses in Ayurveda, from treating respiratory ailments and digestive problems to promoting long variety and spiritual well- being. It is known for its various therapeutic properties including anti-inflammatory, anti-microbial , and antioxidant properties..

Peppermint- Mentha piperita L. is an important medicinal herb worldwide, apart from its potent Uses as flavouring agent in cosmetics, pharmaceutical products amongst others. Quality of M. piperita L. and efficacy are reported to be best. It’s widely cultivated for it’s essential oil , which is used in various products, including culinary, medicinal and cosmetic applications. Peppermint is known for its potential benefits in relieving digestive issues and headaches.

Lavender oil- Inhalation of lavender oil is also reported to be of benefit in pain relief. Lavender oil ass been shown into an effective short-term treatment for lower back pain.

Coconut oil-It has a moisturizing effect when applied to the skin. People commonly use coconut oil for eczema and growth in premature infants. It’s also used for psoriasis, obesity, breast cancer, heart disease, MS and many conditions.

MATERIALS AND REQUIREMENT-

Peppermint oil [20ml] , Lavender oil [20ml] , Tulsi oil [ 20 ml] ,Coconut oil [ 40ml]

GLASSWARES-Beakers , Glass rod, Conical flask , Volumetric flask.

Table no 1: List of ingredients used in the preparations of Herbal Roll-on

METHOD OF PREPARATION- the technique used to prepare herbal roll-on is a simple blending process. It involves the simple mixing of all the ingredients based on the formulation mentioned in table no.2.                                                 

Table no 2: Formulation for Herbal Roll-on:

Evaluation tests of herbal roll on:

Organoleptic Evaluation:  the herbal roll-on was evaluated for its organoleptic properties such as color, odor, and texture.

Removal: Roll-on is applied on the skin and removed by washing with tap water.

Irritancy test: Roll on is applied on the skin and checked for redness, edema, inflammation, and irritation.

Test for microbial growth: The Formulated roll-on was inoculated on the agar media plates by streak plate method  and control was  prepared by excluding the cream. The plates were placed into the incubator and incubated at 37°C for 24 hours. After the incubation period, plates were taken out and checked for microbial growth by comparing them with the control.

pH Evaluation: The pH of the 1% roll-on solution was measured using a digital pH meter (Beckman, Germany).

After feel: emolliency, slipperiness and residue left after roll-on application is observed.

Stability test: Stability testing of the prepared roll- on  was  performed  to  keep  the  samples  at accelerated temperature conditions. Different roll- on  containers  were  kept  at  an  accelerated temperature of 4°C, Room temperature and 47°C, respectively.

RESULTS AND DISCUSSION

After formulating the herbal roll-on, evaluation tests were done and compared with the marketed preparation (amrutanjan roll-on). The results are tabulated in a table no.3. Based on the results of evaluation studies, the herbal roll-on shows similar reports as per marketed preparation.

         Table no 3: Comparison of formulated Herbal Roll-on with marketed roll-on