View Article

  • Niosomes: A Review Of Drug Delivery System
  • 1M. Pharmacy( Pharmaceutics)Student at R. G. Sapkal College of Pharmacy, Anjeneri, Nashik, Maharashtra-India
    2M. Pharmacy( Pharmaceutics)Student at R. G. Sapkal College of Pharmacy, Anjeneri, Nashik, Maharashtra-India
    3Head of Department (Pharmaceutics)R. G. Sapkal College of Pharmacy, Anjeneri, Nashik, Maharashtra-India
    4Principal R. G. Sapkal College of Pharmacy, Anjeneri, Nashik, Maharashtra-India
     

Abstract

In the past few years, there has been a significant change in the way infectious disease management and vaccination practices are carried out. With the development of biotechnology and genetic engineering, numerous biologicals targeted at certain diseases have been developed; additionally, the efficient distribution of these biologicals has received attention. Comparatively speaking, niosomes are less expensive, more stable, nontoxic, and biodegradable than liposomes because they are made of non-ionic surfactants. However, they are more stable than liposomes during the production and storage processes. This paper examines the recent surge in interest in niosomes across several scientific fields, with a focus on medical applications. A thorough overview of niosome types, characterization, applications, and preparation methods is also given in this article.

Keywords

Niosomes, Drug delivery System, Targeted drug delivery, Lamilar

Reference

  1. Kazi KM, Mandal AS, Biswas N, Guha A, Chatterjee S, Behera M, Kuotsu K. Niosome: a future of targeted drug delivery systems. Journal of advanced pharmaceutical technology & research. 2010 Oct;1(4):374.
  2. Ag Seleci D, Seleci M, Walter JG, Stahl F, Scheper T. Niosomes as nanoparticular drug carriers: fundamentals and recent applications. Journal of nanomaterials. 2016 Oct;2016.
  3. Jain NK. Introduction to novel drug delivery systems. Transdermal Drug Delivery. 2010;1:97-117.
  4. Yeo PL, Lim CL, Chye SM, Ling AP, Koh RY. Niosomes: a review of their structure, properties, methods of preparation, and medical applications. Asian Biomed. 2017 Aug 1;11(4):301-14.
  5. Kaur D, Kumar S. Niosomes: present scenario and future aspects. Journal of drug delivery and therapeutics. 2018 Sep 6;8(5):35-43.
  6. Sharma D, Ali AA, Aate JR. Niosomes as Novel Drug Delivery System: Review Article. PharmaTutor, 2018; 6 (3): 58-65.
  7. Chandu VP, Arunachalam A, Jeganath S, Yamini K, Tharangini K, Chaitanya G. Niosomes: a novel drug delivery system. International journal of novel trends in pharmaceutical sciences. 2012 Feb;2(1):25-31.
  8. Diljyot K. Niosomes: a new approach to targeted drug delivery. Int J Pharm Phytopharm Res. 2012;2(1):53-9.
  9. Shakya V, Bansal BK. Niosomes: a novel trend in drug delivery. International Journal of Research and Development in Pharmacy & Life Sciences. 2014 Jul 15;3(4):1036-41.
  10. Mawazi SM, Ann TJ, Widodo RT. Application of Niosomes in Cosmetics: A Systematic Review. Cosmetics. 2022 Nov 25;9(6):127.
  11. Allen TM. Liposomal drug formulations: rationale for development and what we can expect for the future. Drugs. 1998 Nov;56:747-56.
  12. Mahale NB, Thakkar PD, Mali RG, Walunj DR, Chaudhari SR. Niosomes: novel sustained release nonionic stable vesicular systems—an overview. Advances in colloid and interface science. 2012 Nov 15;183:46-54.
  13. Azmin MN, Florence AT, Handjani?Vila RM, Stuart JF, Vanlerberghe G, Whittaker JS. The effect of non?ionic surfactant vesicle (niosome) entrapment on the absorption and distribution of methotrexate in mice. Journal of pharmacy and pharmacology. 1985 Apr;37(4):237-42.
  14. Szoka Jr F, Papahadjopoulos D. Comparative properties and methods of preparation of lipid vesicles (liposomes). Annual review of biophysics and bioengineering. 1980 Jun;9(1):467-508.
  15. Brewer JM, Alexander J. The adjuvant activity of non-ionic surfactant vesicles (niosomes) on the BALB/c humoral response to bovine serum albumin. Immunology. 1992 Apr;75(4):570.
  16. Malhotra M, Jain NK. Niosomes: A Controlled and Novel Drug delivery System. Indian Drugs. 1994;31(3):81-86.
  17. Devi SG, Udupa N. Niosomal sumatriptan succinate for nasal administration. Indian Journal of Pharmaceutical Sciences. 2000;62(6):479-81.
  18. Khandare JN, Madhavi G, Tamhankar BM. Niosomes-novel drug delivery system. Eastern Pharmacist. 1994;37:61-.64.
  19. Rogerson AC, Cummings J, Willmott N, Florence AT. The distribution of doxorubicin in mice following administration in niosomes. Journal of pharmacy and pharmacology. 1988 May;40(5):337-42.
  20. Biju S, Talegaonkar S, Mishra P, Khar R. Vesicular systems: an overview. Indian journal of pharmaceutical sciences. 2006 Mar 1;68(2).
  21. Uchegbu IF, Vyas SP. Non-ionic surfactant based vesicles (niosomes) in drug delivery. International journal of pharmaceutics. 1998 Oct 15;172(1-2):33-70.
  22. Hunter CA, Dolan TF, Coombs GH, Baillie AJ. Vesicular systems (niosomes and liposomes) for delivery of sodium stibogluconate in experimental murine visceral leishmaniasis. Journal of pharmacy and pharmacology. 1988 Mar;40(3):161-165.
  23. Breimer DD, Speiser P. Topics in pharmaceutical sciences. InInternational Congress of Pharmaceutical Sciences of FIP 1981: Vienna, Austria) 1981. Sole distributors for the USA and Canada, Elsevier North-Holland.
  24. Uchegbu LF. Synthetic surfactant vesicles: niosomes and other non-phospholipid vesicular systems. CRC Press; 2000 Feb 23.
  25. Harwood BG. Interfacial Phenomena in Drug Delivery and Targeting. Switzerland: Academic Publishers. 1995:154-155.
  26. Gregoriadis G. Targeting of drugs: implications in medicine. The Lancet. 1981 Aug 1;318(8240):241-246.
  27. Weissmann G, Bloomgarden D, Kaplan R, Cohen C, Hoffstein S, Collins T, Gotlieb A, Nagle D. A general method for the introduction of enzymes, by means of immunoglobulin-coated liposomes, into lysosomes of deficient cells. Proceedings of the National Academy of Sciences. 1975 Jan;72(1):88-92.
  28. Moser P et al: Niosomes d’hémoglobine, Preparation, proprietes physicochimiques oxyphoriques, stabilite. Pharma Acta Helv, 1989, (64), 192-202.
  29. Aggarwal D, Garg A, Kaur IP. Development of a topical niosomal preparation of acetazolamide: preparation and evaluation. Journal of Pharmacy and Pharmacology. 2004 Dec;56(12):1509-17.
  30. Chen S, Hanning S, Falconer J, Locke M, Wen J. Recent advances in non-ionic surfactant vesicles (niosomes): Fabrication, characterization, pharmaceutical and cosmetic applications. European journal of pharmaceutics and biopharmaceutics. 2019 Nov 1;144:18-39.
  31. Pinto CS, Dos Santos EP, Mansur CR. Niosomes as nano-delivery systems in the pharmaceutical field. Critical Reviews™ in Therapeutic Drug Carrier Systems. 2016;33(2).
  32. Manosroi A, Chankhampan C, Manosroi W, Manosroi J. Transdermal absorption enhancement of papain loaded in elastic niosomes incorporated in gel for scar treatment. European journal of pharmaceutical sciences. 2013 Feb 14;48(3):474-83

Photo
Pradnya H. Kapse
Corresponding author

M pharmacy (pharmaceutics) student at R.G.Sapkal college of Pharmacy ,Anjaneri, Nashik, Maharashtra, India.

Photo
Vrushali S. Gangurde
Co-author

M pharmacy (pharmaceutics) student at R.G.Sapkal college of Pharmacy ,Anjaneri, Nashik, Maharashtra, India.

Photo
Khanderao Jadhav
Co-author

Head of Department (Pharmaceutics) KCT’s R. G. Sapkal College of Pharmacy, Anjeneri, Nashik, Maharashtra-India

Photo
Rishikesh Bachhav
Co-author

Principal KCT’s R. G. Sapkal College of Pharmacy, Anjeneri, Nashik, Maharashtra-India

Pradnya H. Kapse, Vrushali S. Gangurde, Khanderao Jadhav, Rishikesh Bachhav, Niosomes: A Review Of Drug Delivery System, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 1, 698-706. https://doi.org/10.5281/zenodo.10575772

More related articles
Formulation And Evaluation of Polyherbal Capsules ...
Adhithyakrishna K., Rahna K., Arisha K. V., Bind Jahsha, Priya Ab...
Concept And Recent Advancement In Tablet Coating T...
Shrikant S. Dongare, Mr. Dnyaneshwar S. Vyavhare, Dr. Megha T. Sa...
Transdermal Drug Delivery System...
Sayali shankhapal, Vaishnavi pandav, Rutuja jaiswal, Sonali kalam...
Xylazine With Opioid Cause Epidemic: Review of Cases, Statistics, Mode of Action...
Rahul Rakesh Vishwakarma, Prajakta Dattatraya Gawade, Manasi Vishwas Shelke , Piyush Lekhraj Yadav ,...
A Review on: Evolution and System of Pharmacovigilances ...
Sakshi Kodilkar , Sonal Kumbhar, Dr. N. B. Chougule, Sakshi Raghunath Patil , Aditi Maruti Mahanwar ...
Pharmacognostic Studies, Phytochemical Screening And Physicochemical Analysis Of...
Munish choudhary , Dev Prakash Dahiya, Chinu Kumari , Bhopesh Kumar, Anita, Dinesh Kumar Thakur, ...
Related Articles
Effective Communication In Pharmacovigilance...
Prajakta Pujari , Sonali Magdum, Kajal Shinde, Darshani Taral, Prajakta Chaugule, Sadhana Pujari, Ra...
Hydrogels ...
Disha P. Wankhede, Laxmi S. Deshmukh, Damini A. Mundhare, Nandakishor B. Deshmukh, Swati P. Deshmukh...
A Comprehensive Review On Phytomolecules Used In Formulation Of Lipstick ...
S. A. Vadivel, S. Anbazhagan, M. Logesh, N. Mathibalan, J. Pradeepkumar, R. Snegha, ...
Formulation And Evaluation of Polyherbal Capsules for Antidiabetic Activity...
Adhithyakrishna K., Rahna K., Arisha K. V., Bind Jahsha, Priya Abraham, ...
More related articles
Formulation And Evaluation of Polyherbal Capsules for Antidiabetic Activity...
Adhithyakrishna K., Rahna K., Arisha K. V., Bind Jahsha, Priya Abraham, ...
Concept And Recent Advancement In Tablet Coating Technologies: A Comprehensive R...
Shrikant S. Dongare, Mr. Dnyaneshwar S. Vyavhare, Dr. Megha T. Salve, ...
Transdermal Drug Delivery System...
Sayali shankhapal, Vaishnavi pandav, Rutuja jaiswal, Sonali kalam, ...
Formulation And Evaluation of Polyherbal Capsules for Antidiabetic Activity...
Adhithyakrishna K., Rahna K., Arisha K. V., Bind Jahsha, Priya Abraham, ...
Concept And Recent Advancement In Tablet Coating Technologies: A Comprehensive R...
Shrikant S. Dongare, Mr. Dnyaneshwar S. Vyavhare, Dr. Megha T. Salve, ...
Transdermal Drug Delivery System...
Sayali shankhapal, Vaishnavi pandav, Rutuja jaiswal, Sonali kalam, ...