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Abstract

The goal was to create in-vitro anti-inflammatory activity of glochidion zeylanicum. Leaves extract and its characterization. The drug was evaluated by using different in-vitro anti-inflammatory activity. GC-MS, UV, and FT-IR were used for the characterization of hydromethanolic leaf extract. According to the findings, Glochidion Zeylenicum A. Juss by preventing the hypnotically induced hemolysis of HRBCs in a dose-dependent manner (25, 50, 75, 100 ?g/mL), hydromethanolic extract was able to provide membrane stabilization. The Glochidion Zeylenicum A. Juss. extract was also capable of inhibiting HRBCs at 58.42% which was comparable to that of diclofenac sodium at 74.73%. When compared with hydromethanolic extract methanolic extract showed a good anti-inflammatory effect. From the current research, we can conclude that glochidion zeylanicum A. Juss. Possesses an appreciable anti-inflammatory effect against human red blood membrane stabilization assay. Further studies are required to determine the possible mechanism behind its anti-inflammatory action.

Keywords

Alzheimer's disease (AD), Acetylcholinesterase (AChE), Eburnane Alkaloids, Lead Molecules

Reference

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Eknath V. Unde
Corresponding author

Dr. Ithape Institute of Pharmacy, Sangamner

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Sneha B. Fand
Co-author

Arihant College of Pharmacy A. Nagar

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Amol S. Darade
Co-author

Dr. Ithape Institute of Pharmacy, Sangamner

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Ganesh R. Gosavi
Co-author

Dr. Ithape Institute of Pharmacy, Sangamner

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Archana S. Murgunde
Co-author

Eknath V. Unde, Snehal B. Fand, Amol S. Darade, Ganesh R. Gosavi, In- Vitro Anti-inflammatory Activity Of Glochidion Zeylanicum A. Juss. Leaves Extract And It’s Characterization, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 1, 831-840. https://doi.org/10.5281/zenodo.10569171

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