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Abstract

Herbal cosmeceuticals often contain plant parts that are antimicrobial, antioxidant, and anti-aging. The safest products to use on a regular basis are herbal cosmetics, which have no known negative effects, and cosmeceuticals, which affect the biological function of Variou skin. Herbs are utilized to clean and improve the appearance of the skin. The active ingredients in this preparation include almond shells, rice powder, sandalwood, turmeric, honey, aloe vera, rose essence, lemon grass, cucumber juice, and almond oil. The gel is made with various grades of tamarind gum. Ritha was put to the gel along with other components. A number of characteristics, including, appearance, pH, viscosity, spread capacity, washability, and irritation were assessed for the manufactured gel. The formulations demonstrated satisfactory homogeneity, spreadability, pH, appearance, and ease of removal. During irritancy testing, the formulation exhibits no signs of redness, edema, inflammation, or irritation. These formulations have been confirmed to satisfy all necessary characterizations and are safe for use on skin. As a result, the created mixture works well as a scrub to help maintain skin that is radiant and healthy.

Keywords

Scrub, Almond shell, Glowing skin, Herbal, Gel, Exfoliating face scrub with low negative effects and good scouring properties. Herbal Face Toner, Side Effects, Hygiene, Antidepressant Activity

Introduction

People have enhanced their attractiveness with naturally occurring materials since ancient times.[1] It is well known that cosmetics are the goods that provide a user more beauty and enhancement.[2] Historically, cosmetics were primarily made of naturally occurring materials. However, as science advanced and time passed, a number of chemicals that are said to confer or enhance beauty emerged and were employed as makeup. The cosmetics industry these days primarily concentrates on the manufacture of herbal products since, although using these chemical-based products might temporarily enhance beauty, doing so over an extended period of time damages our skin [3]. In addition to being entirely chemical-free, the prepared face toner will soothe skin and shield it from sunburn. By eliminating surface-level skin cells and promoting sub-epidermal layer cell growth, herbal exfoliates mitigate age-related alterations and environmental assaults [4]. The rate of cell turnover significantly decreases with age. The bulk of dead cells on the surface of the face stay there for a longer period of time, can Highlight fine.  lines and provide a lifeless complexion dreary appearance [5]. The skin's surface must be washed frequently in order. to get rid of dead cells, crusts, sebus and other secretions, grin, and applied makeup [help maintain health and attractiveness. 6]. Exfoliating the skin helps to deeply clean and brighten it by eliminating these dead skin cells. This can be done physically with a scrub or by using herbal medicines that contain vitamins and antioxidants. antiseptics, and anti-aging ingredients. The only essential oil that will vary depending on the skin type is the one used as a scrub ingredient. Three varieties of skin exist: dry, oily, and sensitive. [7] It is advisable to gently massage all regions of the skin after applying the scrub.  gel to promote blood circulation and oxygenation. [8]

ALMOND SHELLS

 Almond shell is a natural, biodegradable abrasive that can be added to cleansers and cosmetic formulas. Almond Shell comes in a range of particle sizes, from super fine to coarse, and is free of fillers and additives.

Fig no. 1

ALMOND OIL

Vitamin E can be used to address low skin vitamin E levels. This vitamin protects your cells and maintains the health of your organs These pills or capsules can be taken orally with a glass of water as instructed. It could be advantageous to take this medicine with food.

Fig no. 2

ROSE ESSENCE

Together with the health benefits of vitamins K, C, and B, rose water also possesses a number of antimicrobial properties. It also has a good number of antioxidants.[9]

Fig no. 3

TURMERIC

 Curcuma longa, also known as Haridra, has anti-inflammatory and anti-allergic qualities. It's the best blood purifier, and it helps heal wounds. Since it has the greatest blood purifying effect, all ailments resulting from blood impurities are treated with it. Haridra delays the appearance of age signs like wrinkles by reviving and rejuvenating the skin. (Excellent as a preservative when used) [10]

Fig no.4

SANDALWOOD

Sandalwood's astringent and antibacterial qualities help the skin become less moisturised, target active acne, and effectively reduce scars and pigmentation.

Fig no.5

HONEY

On its own, honey works well as a mild face cleanser and natural exfoliant. Additionally, you can mix a few drops with your regular face cleanser. Alternatively, mix it with equal amounts baking soda to create a mild yet efficient face scrub.

Fig no. 6

RICE FLOWER

The high carbohydrate content of rice flour will help battle infections that cause acne. It removes dead skin and has astringent and protective properties.

Fig no, 7

RITHA

Soapnut's potent moisturizing properties protect skin from drying out, keep it hydrated, and leave it smooth and radiant. Strong antibacterial and Anti-inflammatory qualities are used to treat skin problems. such as psoriasis, eczema, and acne.

Fig no. 8

ALOE VERA

Is the common name for aloe vera. During the first phytochemical screening, alkaloids, glycosides, steroids, triterpenoids, carbohydrates, polyphenols, and saponins were found. It belongs to the Asphodelaceae (Lilacaceae) family.


Fig no.9

CUCUMBER JUICE

 Organic cucumber juice, sourced from India, is high in antioxidants that help heal and soothe skin damaged by the sun. Cucumber leaves your skin feeling clear and renewed by decreasing the appearance of sun spots and tan lines. India is the original home of cucumbers. It provides the most favourable climate for its development.

Fig no.10

LEMON GRASS

 Lemongrass aids in detoxification and deep cleansing. This ingredient works wonders in scrubs and masks to help remove dirt Impurities from the skin's surface are removed when skin needs a little extra TLC.

Fig no.11

TAMARIND GUM

 Tamarind gum is derived from the endosperm of tamarind tree (Tamarindus indica linn) seeds and is used in food, paper, and textile industries, among other things. It serves as a stabilizer and emulsifier in the food business.

Fig no. 12

TONER

After washing your face, toner eliminates any remaining dirt, debris, and pollutants that have become lodged in your skin pores. Effect of the Toner on the Skin: These days, skin toners are used increasingly as cosmeceuticals with several uses, such as rehydrating skin, regulating pH, tightening pores, and decreasing inflammation, and even acting as an antisepsis agent, due to the variety and abundance of the goods.

Table No.1: Plant Profile

Sr no

Ingredient

Kingdom

Order

Family

Genus

Species

Class

1

Almond shells

Plantae

Rosaceae’s

Rosaceae

Prunus

P. Dulcis

_

2

Almond oil

Plantae

Rosaceae’s

Rosaceae

Prunus

P. Dulcis

_

3

Rose essence

Plantae

Rosales

Rosaceae

Rosa

Canina

Angiosperms

4

Turmeric

Plantae

Zingiber ales

Zingiberoside

Curcuma

C. longa

_

5

Sandalwood

Plantae

Santalaes

Sanatalaceaes

_

_

Dictoyledonae

6

Honey

Animalia

Hymenoptera

Apidae

Apis

_

Insecta

7

Rice flower

Plantae

Cyperales

Poaceae Barnhart - Grass family

_

Liliopsida - Monocotyledons

_

8

Ritha

Plantae

_

Bagridae

Ritha

R.ritha

Actinopterygii

9

Aloe vera

Plantae

Asparagus’s

Liliaceae

Aloe

_

Liliopsid

10

Cucumber

Plantae

Cucurbitale

Cucurbitaceae

Cucumis

C. Sativus

_

11

Lemon grass

Plantae

Poales

Poaceae

Cymbopod

Flexuous

Liliopsida

12

Tamariend gum

Plantae

Fabales

Tamaridus

T.indica

_

Magnoliopsida

METHODOLOGY

TONER

We bought fresh cucumbers, aloe vera, and roses from the Pune local market. Methanol and carbopol 934 were acquired from SD Fine Chemical Ltd. located in Mumbai. Analytical grade compounds were employed for all other substances.

Table no.2: TEST 1

Ingredients

Uses

Quantity

Almond shell

 Bio based cosmetics use for face pores opening

10%

Almond oil

Soothe and hydrate your skin and hair

5.5%

Rose essence

Perfume

Q. S

Turmeric

Colouring agent and anti-septic

0.10%

Sandalwood

Whitening of skin and cooling effect

10%

Honey

Smoothing texture

5%

Ritha

Cleansing agent 

10%

Rice flour

Scrubbing to the skin

2%

Aloe vera

Smoothing effect, Cooling, moistening to the skin

5%

Cucumber juice

Reduce wrinkles

6%

Lemon grass

Removing impurities, detoxify the skin and leave it feeling clean and clear

3%

Tamarind gum

Improving skin elasticity and also use as a base

45%

Conclusion 1

Assemble the mixture with 100% quantity. We discovered some issues during formulation preparation; thus, we will formulate the second batch. The lemon grass in batch 1 exhibits minor facial discomfort. Because of the open pores on the skin caused by the properties of rice and almond shell, we chose to take a tiny amount of lemon grass because it seems to cause some irritation in that area.

Table no.3: TEST 2

Ingredients

Uses

Quantity

Almond shell

Bio based cosmetics use for face pores opening

10%

Almond oil

Soothe and hydrate your skin and hair

5.5%

Rose essence

Perfume

Q. S

Turmeric

Colouring agent and anti-septic

0.10%

Sandalwood

Whitening of skin and cooling effect

10%

Honey

Smoothing texture

5%

Ritha

Cleansing agent

10%

Rice flour

Scrubbing to the skin

2%

Aloe vera

Smoothing effect, Cooling, moistening to the skin

7%

Cucumber juice

Reduce wrinkles

6%

Lemon grass

Removing impurities, detoxify the skin and leave it feeling clean and clear

1%

Tamarind gum

Improving skin elasticity and also use as a base

45%

Conclusion 2

In the second test, we will use more aloe vera and less lemon grass to get the desired cooling and smoothing effects. After using the scrub, your face will feel smoother and cooler, although there will be some slight discomfort from the lemon grass. Thus, we'll choose to eliminate the lemon grass in the recipe.

Table no.4: TEST 3

Ingredients

Uses

Quantity

Almond shell

Bio based cosmetics use for face pores opening

10%

Almond oil

Soothe and hydrate your skin and hair

5.5%

Rose essence

Perfume

Q. S

Turmeric

Colouring agent and anti-septic

0.10%

Sandalwood

Whitening of skin and cooling effect

10%

Honey

Smoothing texture

5%

Ritha

Cleansing agent

10%

Rice flour

Scrubbing to the skin

2%

Aloe vera

Smoothing effect, Cooling, moistening to the skin

8%

Cucumber juice

Reduce wrinkles

6%

Tamarind gum

Improving skin elasticity and also use as a base

45%

 

Conclusion 3

Following the removal of the lemon grass, there was no sign of irritation. We will therefore decide to proceed with this formulation, but in order to have the best outcome, we will try batch 4, and when they demonstrate the same outcome, that is good. but in that the rose smell accrued very high concentration so we will also minimize the rose essence.

Table no.5: TEST 4

Ingredients

Uses

Quantity

Almond shell

Bio based cosmetics use for face pores opening

10%

Almond oil

Soothe and hydrate your skin and hair

5.5%

Rose essence

Perfume

Q. S

Turmeric

Colouring agent and anti-septic

0.10%

Sandalwood

Whitening of skin and cooling effect

10%

Honey

Smoothing texture

5%

Ritha

Cleansing agent

10%

Rice flour

Scrubbing to the skin

2%

Aloe vera

Smoothing effect, Cooling, moistening to the skin

8%

Cucumber juice

Reduce wrinkles

6%

Tamarind gum

Improving skin elasticity and also use as a base

45%

 

Conclusion 4

The best outcome, which included minimal discomfort and rose essence that gave off the right scent similar to that of a rose, was discovered in the test 4 final result.

EVALUATION PARAMETER

  • PH

The pH of the generated gel was measured. On the pH paper, a small amount of gel was applied.

  • Sprayability

A tiny bit of gel was applied to one of the two glass slides, and then another glass slide was placed on top of the gel. It was weighted with a wooden object. The area and the amount of time needed for the gel to spread were measured. The gel's area and quantity on the glass slide indicate how well it spreads.

  • Excludability

A tiny amount The gel was placed in a foldable ointment bottle. One end was closed, while the other remained open. The closed side received light pressure. Gel volume and extrusion time were recorded.

  • Irritation

After applying a little amount of gel to the skin, it was rinsed with water. Manual testing was done on formulations that could be readily removed from the skin by washing with water.

  • Foamability

A graduated measuring cylinder was filled with a little amount of gel and water, and the foam was measured. After noting the initial volume, the beaker was shaken ten times, and the final volume was recorded.

  • Washability

After applying a little amount of the gel to the skin and waiting a few minutes, it was found to be non-irritant.

  • Stability

By packing the scrub into plastic containers and keeping it in a humidity chamber with a temperature of 45°C and a relative humidity of 75%, the formulation's stability was examined. For three months, the formulation's stability was assessed once every month. [12]

  • Consistency

By using visual inspection, it was discovered to be semi-solid.

  • Patch test

Patch testing is a proven technique for identifying hypersensitivity and assessing the possibility of a certain material to trigger the patient's allergic reaction
skin. A patch test exposes a tiny section of skin to those substances in diluted form, with the specific goal of be investigated. The skin's response to the formulation in a patch test is noticed after two to three days.

RESULT & DISCUSSION

Table no.6: Test 1

Performance

Observation

PH

6.57

Spray ability

8cm

Excludability

1-2 gm

Irritation

discovered annoyance

Foamability

Absent foam

Washability

Easily washable

Stability

Stable at room temperature

Consistency

Good

Odour

Strong smell of rose

Colour

Crewed white

Grittiness

Gritty particle present

Patch test

Non allergic or No sensitivity but accord some irritation

 

Table no.7: Test 2

Performance

Observation

PH

6.57

Spray ability

8cm

Excludability

1-2 gm

Irritation

Small amount discovered annoyance

Foamability

Absent foam

Washability

Easily washable

Stability

Stable at room temperature

Consistency

Good

Odour

Strong smell of rose

Colour

Crewed white

Grittiness

Gritty particle present

Patch test

Non allergic or No sensitivity 

Table no.8: Test 3

Performance

Observation

PH

4.64

Spray ability

8cm

Excludability

1-2 gm

Irritation

No irritation

Foamability

Absent foam

Washability

Easily washable

Stability

Stable at room temperature

Consistency

Good

Odour

Strong smell of rose

Colour

Crewed white

Grittiness

Gritty particle present

Patch test

Non allergic or No sensitivity 

Table no.9: Test 4

Performance

Observation

PH

6.9

Spray ability

8cm

Excludability

1-2 gm

Irritation

No irritation

Foamability

Absent foam

Washability

Easily washable

Stability

Stable at room temperature

Consistency

Good

Odour

Characteristic as rose

Colour

Crewed white

Grittiness

Gritty particle present

Patch test

Non allergic or No sensitivity 

IN SUMMARY

The study attempted to create a toner-infused almond shell scrub. The created mixture was assessed using a range of physical criteria, and upon application, positive outcomes were noted, including the elimination of dead skin cells and the production of smooth, side-effect-free skin. This is a good way to take care of your skin. It's also evident from the formulation tests mentioned above that the herbal gel toner developed has a smoothing, soothing, astringent, and renewing impact on skin. It is non-irritating and suitable for everyday usage to bring out the inherent beauty of human skin. Significant antioxidant activity in the mixture was also discovered, which may account for some of its sun screening properties. In addition to the criteria listed above, the gel toner was determined to have high homogeneity, spreadability, and pH within the skin range. Thus, the gel form of herbal toner can be applied topically to improve the health and renewal of dry, pale skin. It was also discovered that elements such as cucumber and Aloe vera provided the highest effects for hydration and acne.

CONFLICT OF INTEREST

Regarding this investigation, the authors have no conflicts of interest.

ACKNOWLEDGMENTS

For the literature review, the authors are grateful to the Rajarshi Shahu College of Pharmacy Library in Buldana.

REFERENCES

  1. Baumann, Leslie: Botanical ingredients in cosmeceuticals. Journal of drugs in dermatology, 2007; 6: 1-84.
  2. Vaidyanathan R, Anand B: Importance of Chemistry in Herbal Cosmetics and Cosmeceuticals. Research journal of pharmacy and technology, 2017; 10(12): 4460-4462.
  3. Edward Hart: Cosmetics. Journal of the American Chemical Society, 1904; 26: 333-335.
  4. Nilani Packianathan, Ruckmani Kandasamy, Skin Care with Herbal Exfoliants, Functional Plant Science and Biotechnology 5 (Special Issue 1), 94-97 ©2011 Global Science Books.
  5. Aglawe SB, Gayke AU, Khurde A, Mehta D, Mohare T, Pangavane A, Kandalkar S, Preparation and evaluation of polyherbal facial scrub. Journal of Drug Delivery and Therapeutics. 2019; 9(2):61-63
  6. Nemade CT, Baste N. formulation and evaluation of a herbal facial scrub, World Journal of Pharmaceutical Research 3(3):4367-4371.
  7. Garg A, Aggarwal D, Garg S, Singla AK: Spreading of semisolid formulations: an update. Pharmaceutical Technology North America. 2002;26(9):84-105.
  8. Harish NM, Prabhu P, Charyulu RN, Gulzar MA, Subrahmanyam EV: Formulation and evaluation of in situ gels containing clotrimazole for oral candidiasis. Indian Journal of Pharmaceutical Sciences. 2009 Jul;71(4):421-427.
  9. Kumar KK, Sasikanth K, Sabareesh M, Dorababu N. Formulation and evaluation of diacerein cream. Asian J Pharm Clin Res. 2011;4(2):93-8
  10. Kumar KK, Sasikanth K, Sabareesh M, Dorababu N. Formulation and evaluation of diacerein cream. Asian J Pharm Clin Res. 2011;4(2):93-8
  11. Draelos ZD. Astringents, Masks, and Ancillary Skin Care Products. In Textbook of Cosmetic Dermatology, 5thed.; Baran R, Maibach HI, Eds.; CRCPress: Boca Raton, FL, USA. 2017; 178–181
  12. J. Prathyusha, N. S. Yamani, G. Santhosh, A. Aravind, B. Naresh. Formulation 5.
  13. J. Prathyusha, N. S. Yamani, G. Santhosh, A. Aravind, B. Naresh. Formulation and Evaluation of Polyherbal Face Scrubber for Oily Skin in Gel Form. International Journal of Pharmaceutical Sciences and Drug Research 2019; 11(4): 126-128
  14. Jain A, Deveda P, Vyas N, Chauhan J, Development of antifungal emulsion gel based for topical fungal infection, international journal of pharma research and development, 2003; 2(12):18-19.
  15. Barros N A, Robson R R, Assis A R, Mendes M F, Extraction of basil oil (Osimum basilicum.L) using supercritical fluid, Ibroamerican conferences on supercritical fluid, 2013
  16. Bhanu D V, Shanmugam and Lakshmi P K, Development and optimization of novel diclofenac emulgel for topical drug delivery, international journal of comprehensive pharm, 2011; 9(10):1-4.
  17. Prathyusha, al, Formulation and Evaluation of Polyherbal Face Scrubber for Oily Skin in Gel Form, International Journal of Pharmaceutical and Sciences and Drug Research,2019, Vol 11(4): 126- 128.
  18. Daud, F. S., Pande, G., Joshi, M., Pathak, R. and Wankhede, S. (2013). A Study of Antibacterial Effect of Some Selected Essential Oils and Medicinal Herbs against Acne Causing Bacteria. International Journal of Pharmaceutical Science Invention. 2 (1):27-34.
  19. DebjitBhowmik, Harish Gopinath, B Pragati Kumar, S Duraivel Aravind GKP, Sampath Kumar. Medicinal Uses of Punicagranatumand Its Health Benefits; Journal of Pharmacognosy and Phytochemistry, 2013; 1(5).
  20. Bhanu PV, Shanmugam and Lakshmi PK. Development and Optimization of Novel Diclofenac Emulgel for Topical Drug Delivery. International Journal of Comprehensive Pharmacy, 2011; 9(10):1-4

Reference

  1. Baumann, Leslie: Botanical ingredients in cosmeceuticals. Journal of drugs in dermatology, 2007; 6: 1-84.
  2. Vaidyanathan R, Anand B: Importance of Chemistry in Herbal Cosmetics and Cosmeceuticals. Research journal of pharmacy and technology, 2017; 10(12): 4460-4462.
  3. Edward Hart: Cosmetics. Journal of the American Chemical Society, 1904; 26: 333-335.
  4. Nilani Packianathan, Ruckmani Kandasamy, Skin Care with Herbal Exfoliants, Functional Plant Science and Biotechnology 5 (Special Issue 1), 94-97 ©2011 Global Science Books.
  5. Aglawe SB, Gayke AU, Khurde A, Mehta D, Mohare T, Pangavane A, Kandalkar S, Preparation and evaluation of polyherbal facial scrub. Journal of Drug Delivery and Therapeutics. 2019; 9(2):61-63
  6. Nemade CT, Baste N. formulation and evaluation of a herbal facial scrub, World Journal of Pharmaceutical Research 3(3):4367-4371.
  7. Garg A, Aggarwal D, Garg S, Singla AK: Spreading of semisolid formulations: an update. Pharmaceutical Technology North America. 2002;26(9):84-105.
  8. Harish NM, Prabhu P, Charyulu RN, Gulzar MA, Subrahmanyam EV: Formulation and evaluation of in situ gels containing clotrimazole for oral candidiasis. Indian Journal of Pharmaceutical Sciences. 2009 Jul;71(4):421-427.
  9. Kumar KK, Sasikanth K, Sabareesh M, Dorababu N. Formulation and evaluation of diacerein cream. Asian J Pharm Clin Res. 2011;4(2):93-8
  10. Kumar KK, Sasikanth K, Sabareesh M, Dorababu N. Formulation and evaluation of diacerein cream. Asian J Pharm Clin Res. 2011;4(2):93-8
  11. Draelos ZD. Astringents, Masks, and Ancillary Skin Care Products. In Textbook of Cosmetic Dermatology, 5thed.; Baran R, Maibach HI, Eds.; CRCPress: Boca Raton, FL, USA. 2017; 178–181
  12. J. Prathyusha, N. S. Yamani, G. Santhosh, A. Aravind, B. Naresh. Formulation 5.
  13. J. Prathyusha, N. S. Yamani, G. Santhosh, A. Aravind, B. Naresh. Formulation and Evaluation of Polyherbal Face Scrubber for Oily Skin in Gel Form. International Journal of Pharmaceutical Sciences and Drug Research 2019; 11(4): 126-128
  14. Jain A, Deveda P, Vyas N, Chauhan J, Development of antifungal emulsion gel based for topical fungal infection, international journal of pharma research and development, 2003; 2(12):18-19.
  15. Barros N A, Robson R R, Assis A R, Mendes M F, Extraction of basil oil (Osimum basilicum.L) using supercritical fluid, Ibroamerican conferences on supercritical fluid, 2013
  16. Bhanu D V, Shanmugam and Lakshmi P K, Development and optimization of novel diclofenac emulgel for topical drug delivery, international journal of comprehensive pharm, 2011; 9(10):1-4.
  17. Prathyusha, al, Formulation and Evaluation of Polyherbal Face Scrubber for Oily Skin in Gel Form, International Journal of Pharmaceutical and Sciences and Drug Research,2019, Vol 11(4): 126- 128.
  18. Daud, F. S., Pande, G., Joshi, M., Pathak, R. and Wankhede, S. (2013). A Study of Antibacterial Effect of Some Selected Essential Oils and Medicinal Herbs against Acne Causing Bacteria. International Journal of Pharmaceutical Science Invention. 2 (1):27-34.
  19. DebjitBhowmik, Harish Gopinath, B Pragati Kumar, S Duraivel Aravind GKP, Sampath Kumar. Medicinal Uses of Punicagranatumand Its Health Benefits; Journal of Pharmacognosy and Phytochemistry, 2013; 1(5).
  20. Bhanu PV, Shanmugam and Lakshmi PK. Development and Optimization of Novel Diclofenac Emulgel for Topical Drug Delivery. International Journal of Comprehensive Pharmacy, 2011; 9(10):1-4

Photo
Aishwarya Jaiswal
Corresponding author

M.Pharm. Scholar, Dept. of Quality Assurance, Rajarshi Shahu College of Pharmacy, Buldhana, Dist-Buldana, MS, India

Photo
Sumit Mundhe
Co-author

M.Pharm. Scholar, Dept. of Pharmaceuties, Rajarshi Shahu College of Pharmacy, Buldhana, Dist-Buldana, MS, India

Photo
Vaishnavi Kherdekar
Co-author

M.Pharm. Scholar, Dept. of Pharmaceuties, Rajarshi Shahu College of Pharmacy, Buldhana, Dist-Buldana, MS, India

Photo
Shrikant Chavan
Co-author

M.Pharm. Scholar, Dept. of Pharmaceuties, Rajarshi Shahu College of Pharmacy, Buldhana, Dist-Buldana, MS, India

Photo
Sakshi Bodwade
Co-author

M.Pharm. Scholar, Dept. of Pharmaceuties, Rajarshi Shahu College of Pharmacy, Buldhana, Dist-Buldana, MS, India

Photo
Dr. Ashish Gawai
Co-author

prof. Ph. D  M.pharm Ph.D Rajarshi Shahu College of Pharmacy, Buldhana, Dist-Buldhana, MS, India-443001

Photo
Dr. Shirish Jain
Co-author

 Principal of Rajarshi Shahu College of Pharmacy, Buldhana, Dist-Buldhana, MS, India-443001

Aishwarya Jaiswal*, Sumit Mundhe, Vaishnavi Kherdekar, Shrikant Chavan, Sakshi Bodwade, Dr. Ashish Gawai, Dr. Shirish Jain, Formulation and Evaluation of Scrub by using Almond Shells with Toning Effect, Int. J. of Pharm. Sci., 2025, Vol 3, Issue 3, 3367-3377. https://doi.org/10.5281/zenodo.15113145

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