Formulation and evaluation of herbal cough syrup

Herbal cough syrup is defined as decoction with honey or sugar. Herbal cough syrup is formulated using crude drugs as Vasaka, Marshmallow, Elderberry, Cinnamon & Thyme etc. Herbal cough syrup is used in both dry & wet cough. The cough syrup medication is a liquid dosage form use of oral liquid pharmaceutical has been confirm on basic ease of administration to those people to have the problem in swallowing of solid dosage form of medication. Syrup is a concentrated solution contains sugar/honey and purified water. When syrup without a medication but the flavouring agent present are known as flavoured syrup or non-medicated syrup. Flavoured syrup are frequently used as a vehicle for unpleasant test of medication results is medicated syrups. Syrup is very prominent delivery vehicle use for the anti-tussive medication because they give a more soothing to swallow then the table and capsule.

Literature Review: -

1. WHO: Radix Althaeae. Who Monographs On Selected Medicinal Plants Vol 2. Geneva, World Health Organization, 2004.
2. ESCOP: Althaeae Radix Marshmallow Root; In European Scientific Co Operation On Phytotherapy (Ed): ESCOP Monographs: The Scientific Foundation For Herbal Medicinal Products Stuttgart, Thieme, 2003, Pp 32-35.
3. Kumar Et Al: (2017) Further Described Marshmallow Roots As Containing Flavonoids ( Such As Kaempferol) And Phenolic Acid, Which Contribute To Antioxidant Activity
4. Duke (2002) Summarized Traditional Applications, Emphasizing Its Demulcent ( Soothing ) And Emollient ( Moisturizing ) Properties. Modern Clinical Observation Suggest Marshmallow Root May Help In Managing Dry Cough, Gastritis And Skin Inflammation (Wagner Et Al., 1989).
5. Kraft (1999) Noted That The High Mucilage Content Creates A Protective Layer Over Irritated Mucosa, Particularly Effective In Cases Of Dry Cough And Pharyngitis. Clinical Data Suggest Symptom Relief Within Days Of Marshmallow Based Syrup Use.

Classification of Cough: -

• Acute cough – Not more than 3 weeks duration.
• Chronic cough –More than 3 weeks.
• Dry cough – No mucous secretion

• Wet cough – With mucous secretion.

ADVANTAGE

• Provide protection from allergic cough.
• Easily available.
• Lower cost.
• Good patient compliance.
• Herbs grow in common places.
• Not required prescription
• No side effects

DISADVANTAGES: -

• No proper regulations.

• Herbs interact with modern medicines.
• Lack of dosage instruction.
• Delayed onset of action.

Aim And Objective:

Aim: Formulation And Evaluation Of Herbal Cough Syrup.

Objective Of the Study:

1. soothing throat irritation

2. reducing inflammation

3. natural remedy for respiratory issues

4. relieving cough symptoms

Plan Of Work:

The present proposed research work is planned as follows:

Formulation Table: -

Method Of Preparation of Herbal Cough Syrup: -

? Preparation of Extract by Decoction method: -

Weigh accurately each ingredient except honey   Ingredients are mixed using 500ml water in round bottom flask flask attach to the reflex condenser and mixed material was boil under carefully by using water bath for 3 hrs.  Boil until total volume become one forth part of solution. Then liquid extract was cooled and filtered.

Preparation final cough syrup:-

To prepared final cough syrup 45% of honey was mixed slowly side by side continuous stirring in decoction solution. Herbal cough syrup was prepared and use for cough.