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Abstract

Acne vulgaris, commonly referred to as Yuvanpidika in Ayurveda, is a common skin disorder affecting adolescents and adults. According to Ayurveda, the imbalance in the Tridoshas—Vata, Pitta, and Kapha—along with the accumulation of toxins (Ama), leads to the formation of acne. Ayurvedic treatments aim to restore dosha balance and purify the blood through the use of herbal remedies, dietary modifications, and lifestyle changes. Herbs such as Neem (Azadirachta indica), Turmeric (Curcuma longa), Sandalwood (Santalum album), and Aloe Vera (Aloe barbadensis) have been traditionally used to treat acne due to their anti-inflammatory, antimicrobial, and blood-purifying properties. This review explores the Ayurvedic perspective on acne pathogenesis, key herbs used for treatment, and the potential of these traditional remedies in modern skincare practices.

Keywords

Acne vulgaris, Ayurveda, Yuvanpidika, dhatu, tridosha

Introduction

Acne vulgaris is a prevalent skin condition, affecting millions of individuals, particularly during adolescence. It is characterized by the formation of comedones, papules, pustules, and in some cases, nodules or cysts. The pathogenesis of acne involves several factors such as increased sebum production, follicular hyperkeratinization, bacterial colonization, and inflammation (1, 2). Although conventional treatments, including antibiotics and retinoids, are widely prescribed, they often come with adverse effects like skin irritation, dryness, and antibiotic resistance (3, 4). In recent years, there has been a growing interest in traditional systems of medicine like Ayurveda, which offers a holistic approach to acne management. Ayurveda emphasizes the balance of the Tridoshas (Vata, Pitta, Kapha), along with the elimination of toxins from the body, to maintain healthy skin. Ayurvedic treatments focus on both internal purification and external applications to restore dosha balance and reduce skin inflammation. (5,6,7)

2. Ayurvedic Perspective on Acne (Yuvanpidika):

In Ayurveda, acne is referred to as Yuvanpidika or Tarunyapitika, highlighting its prevalence in young adults and adolescents. The term Yuvanpidika is derived from Yuvan (youth) and Pidika (pimple or eruption), suggesting that this condition is closely associated with adolescence due to hormonal changes and lifestyle factors. (7,8)

Tridosha Imbalance and Acne:

The Ayurvedic concept of health is based on the balance of the three doshas—Vata, Pitta, and Kapha—that regulate bodily functions. Acne is primarily attributed to an imbalance in Pitta and Kapha doshas (5). The excess Pitta leads to increased heat and inflammation in the body, manifesting as redness and pustules on the skin. Kapha imbalance contributes to excessive sebum production, leading to clogged pores and the formation of comedones. In some cases, an aggravated Vata dosha may cause dryness and scaling of the skin. (6,7) Rakta Dhatu (blood) also plays a crucial role in the development of acne. Impurities in the blood, often caused by poor digestion, unhealthy diet, or toxin accumulation (Ama), can lead to skin eruptions. Therefore, Ayurvedic treatments for acne focus on purifying the blood, balancing the doshas, and restoring skin health through internal and external therapies. (7,9,10)

Ayurvedic Classification of Acne

According to Ayurveda, acne can be classified into four types based on the predominant dosha involved:

  • Vataja Yuvanpidika:

Characterized by intense itching, dryness, and blackish discoloration of acne lesions. This type of acne is often linked to an aggravated Vata dosha.

  • Pittaja Yuvanpidika:

Marked by redness, inflammation, and pus-filled pimples. The lesions are hot to the touch, indicating an aggravated Pitta dosha.

  • Kaphaja Yuvanpidika:

Acne lesions are oily, large, and pus-filled, associated with excess Kapha dosha and sebum production.

  • Raktaja Yuvanpidika:

This type of acne is related to blood impurities (Rakta Dushti) and is often associated with painful, inflamed pustules (9). Ayurvedic treatment for acne involves detoxifying the body, regulating the digestive system, and balancing the doshas. The aim is to purify Rakta Dhatu and restore equilibrium within the body.(7,11)

Ayurvedic Herbs for Acne Treatment

Ayurveda has a rich history of using medicinal plants to treat skin disorders, including acne. These herbs are known for their anti-inflammatory, antimicrobial, and antioxidant properties, which are crucial for managing acne. The following herbs are commonly used in Ayurvedic formulations for acne treatment:

Neem (Azadirachta indica)

Neem, known as Nimba in Sanskrit, holds a revered place in Ayurvedic medicine due to its remarkable therapeutic properties. Historically referred to as the “village pharmacy,” neem is celebrated for its potent antimicrobial, anti-inflammatory, and blood-purifying effects. Its broad-spectrum antimicrobial activity makes it an effective remedy for a wide range of skin infections, including acne. (12) Acne is largely driven by bacterial colonization in the skin’s sebaceous glands, particularly by Propionibacterium acnes, which exacerbates inflammation. Neem combats this issue by directly inhibiting bacterial growth, reducing the risk of clogged pores and subsequent infections. Its bioactive compounds, such as nimbin, nimbidin, and quercetin, possess strong antibacterial properties, which make neem highly effective in preventing the proliferation of P. acnes. (1,2,13) Furthermore, neem’s anti-inflammatory properties help reduce the swelling, redness, and discomfort associated with acne lesions. The herb cools the skin, making it particularly suitable for inflamed and pustular acne, which is often a result of excess Pitta dosha. Its ability to balance both Pitta and Kapha doshas ensures that neem is beneficial for acne cases characterized by both excess sebum production (Kapha imbalance) and inflammation (Pitta imbalance). (9,13,14) Neem is also rich in antioxidants, which help neutralize free radicals that contribute to oxidative stress and premature aging. These antioxidants not only prevent acne but also promote faster healing of acne lesions, minimizing the risk of post-inflammatory hyperpigmentation and scarring. Neem can be used in various forms, such as topical pastes, decoctions, and oil applications, making it a versatile and potent component of Ayurvedic acne therapy. (8,12,13)

Turmeric (Curcuma longa)

Turmeric, or Haridra, is regarded as one of the most powerful anti-inflammatory herbs in Ayurveda. Its active component, curcumin, has been the subject of extensive research due to its potent anti-inflammatory, antimicrobial, and antioxidant effects, which are crucial in managing acne and preventing scarring. (14,15) In the context of acne, turmeric's anti-inflammatory properties help reduce the redness, swelling, and irritation that typically accompany pustular and nodular acne. Acne is often aggravated by inflammatory mediators in the skin, and curcumin helps to inhibit these pathways, thus reducing the severity of acne outbreaks. Inflammatory acne lesions, especially those linked to aggravated Pitta dosha, are well-managed by turmeric, which pacifies Pitta's heat and inflammation. (14,15) Turmeric also possesses antimicrobial properties, which help reduce the colonization of acne-causing bacteria like P. acnes. Its antimicrobial action helps prevent the spread of bacteria on the skin, minimizing the formation of new acne lesions. This is particularly useful in treating cystic acne, where deep infection within the skin layers can result in painful nodules. (1,2,15) Another significant benefit of turmeric is its antioxidant activity. The high concentration of curcuminoids helps neutralize free radicals that contribute to skin damage, thereby promoting faster healing of acne lesions. This antioxidant protection prevents post-acne scarring and hyperpigmentation, a common issue in severe acne cases. Additionally, turmeric enhances collagen production and skin regeneration, making it invaluable in treating acne scars and improving skin texture over time.  (8,11,14,15) Turmeric is used both topically in face masks and pastes and internally in decoctions or medicated oils, making it an integral part of Ayurvedic acne management. (8)

Sandalwood (Santalum album)

Sandalwood (Chandan) is a key component in Ayurvedic skincare, particularly for conditions involving heat and inflammation, such as acne. Known for its cooling, soothing, and anti-inflammatory properties, sandalwood is highly effective in treating Pittaja Yuvanpidika, where inflammation and redness are predominant. (8,16)

The cooling nature of sandalwood makes it particularly beneficial for acne characterized by excessive heat and inflamed pustules. It helps to pacify the Pitta dosha, reducing the burning sensation and redness commonly seen in inflammatory acne. The application of sandalwood paste provides an instant cooling effect on the skin, soothing inflamed acne lesions and reducing the size of pimples. (8,11,16) Additionally, sandalwood has antimicrobial properties, which help reduce bacterial activity on the skin, preventing the spread of acne. Its astringent action also helps control excessive oil secretion by shrinking the pores and balancing sebum production, making it an effective treatment for oily and acne-prone skin. (11,16) Sandalwood's ability to lighten scars and improve skin texture is another significant benefit. Regular use of sandalwood for acne helps prevent the development of post-inflammatory hyperpigmentation and enhances the skin’s overall complexion. Ayurvedic practitioners often recommend sandalwood as a face mask or medicated oil, particularly for individuals with sensitive or reactive skin that is prone to inflammation and acne breakouts. (8,16)

Aloe Vera (Aloe barbadensis)

Aloe vera, known as Ghritkumari in Ayurveda, is widely recognized for its hydrating, cooling, and anti-inflammatory properties. It is one of the most versatile herbs used in skincare, especially for soothing acne-prone skin and promoting faster healing. (17) Aloe vera’s anti-inflammatory action helps reduce the redness, irritation, and swelling associated with acne. This is especially beneficial for individuals with sensitive skin, where traditional acne treatments may cause further irritation. The cooling effect of aloe vera provides instant relief to inflamed acne lesions, making it ideal for treating acne caused by excess Pitta dosha. (8) Aloe vera is also rich in polysaccharides and growth hormones that help regenerate the skin and accelerate the healing process of acne lesions. This regenerative property not only aids in the faster resolution of acne but also reduces the risk of scarring and post-acne hyperpigmentation. For individuals dealing with recurrent acne or those prone to acne scars, aloe vera is a natural remedy that prevents the formation of deep scars by promoting collagen synthesis and skin repair. (8,11,17)

Another key benefit of aloe vera is its antimicrobial activity, which helps inhibit the growth of acne-causing bacteria on the skin. The presence of compounds such as aloesin and aloe-emodin gives aloe vera its antibacterial properties, making it useful for treating and preventing acne breakouts. Aloe vera is commonly applied topically as a gel, either on its own or as part of a multi-herb formulation, to cool, heal, and rejuvenate the skin. (17)

Other Ayurvedic Herbs for Acne

  • Manjistha (Rubia cordifolia):

Known for its powerful blood-purifying and anti-inflammatory properties, Manjistha is often used in Ayurvedic formulations to treat acne. It helps detoxify the blood, removing impurities that contribute to skin eruptions and inflammation. Manjistha is also effective in reducing acne scars and improving skin complexion, making it a valuable herb in long-term acne management. (8,11,18)

  • Tulsi (Ocimum sanctum):

Commonly known as holy basil, Tulsi is a potent herb for balancing Kapha dosha and controlling excess oil production. Its strong antimicrobial properties help prevent bacterial infections, while its antioxidant and anti-inflammatory effects help reduce acne inflammation and promote clearer skin. Tulsi is particularly useful in managing oily, acne-prone skin by regulating sebum levels and detoxifying the skin. [8,11,19]


Table 1: Description of various medicinal plants and its pharmacological activity.

 


       
            Screenshot 2024-10-28 182145.png
       

    


Ayurvedic Skincare Practices and Treatments for Acne

Ayurvedic treatments for acne go beyond topical applications and include internal purification, dietary modifications, and lifestyle changes. The following are some of the key practices used to manage acne: (31,32)

Mukhlepa (Herbal Face Applications)

Mukhlepa refers to the application of herbal pastes or masks to treat various skin disorders, including acne. Ayurvedic texts, such as the Charak Samhita and Sushruta Samhita, describe numerous formulations for acne treatment, utilizing herbs like Neem, Turmeric, and Sandalwood.  [7,8,9]


Table 2: Ayurvedic remedies and treatments for different skin diseases


       
            Screenshot 2024-10-28 183704.png
       

    


Table 3: Different mixtures of lepa in ayurveda for seasons


       
            Screenshot 2024-10-28 183456.png
       

    

 

Shodhana Chikitsa (Purification Therapy)

Shodhana Chikitsa aims to remove toxins (Ama) from the body and purify the blood. Panchakarma therapies such as Virechana (purgation) and Raktamokshana (bloodletting) are often recommended for treating acne. These therapies help eliminate excess Pitta and Kapha, reduce inflammation, and prevent the recurrence of acne [9,14].

Dietary and Lifestyle Recommendations in Ayurveda

Ayurveda places great emphasis on diet and lifestyle modifications to balance the doshas and prevent acne flare-ups. The following dietary and lifestyle practices are recommended for managing acne:

  • Dietary Recommendations:

To pacify Pitta and Kapha doshas, Ayurveda recommends avoiding spicy, oily, and heavy foods. Instead, individuals should consume cooling, detoxifying foods such as fresh fruits, vegetables, and whole grains. Herbs like Triphala and Guduchi are often prescribed to improve digestion and eliminate toxins from the body [15].

  • Yoga and Meditation:

Practices like yoga and meditation help reduce stress, a known trigger for acne. Yoga postures such as Sarvangasana (shoulder stand) and Matsyasana (fish pose) are believed to balance the doshas and promote healthy skin. [33]

FUTURE SCOPE:

As Ayurveda gains global recognition, further research is needed to scientifically validate the efficacy of Ayurvedic treatments for acne. Clinical trials should focus on standardizing herbal formulations and exploring advanced drug delivery systems to enhance the bioavailability of Ayurvedic herbs. Moreover, integrating Ayurvedic principles with modern dermatology could lead to innovative, personalized skincare treatments that address the unique needs of individuals based on their dosha constitution.

CONCLUSION:

Ayurveda offers a holistic and natural approach to managing acne, focusing on the underlying causes such as imbalances in the Tridoshas (Vata, Pitta, and Kapha) and the accumulation of toxins (Ama) in the body. The application of Ayurvedic principles not only targets the external symptoms of acne but also seeks to restore internal balance, which is crucial for achieving long-term, sustainable results in skin health. Ayurvedic treatments emphasize the importance of internal purification through dietary adjustments, lifestyle modifications, and the use of herbal remedies, in addition to topical applications. Key Ayurvedic herbs such as Neem, Turmeric, Sandalwood, and Aloe Vera have demonstrated significant potential in treating acne due to their antimicrobial, anti-inflammatory, and skin-healing properties. These herbs help address the primary causes of acne, such as bacterial colonization, excess sebum production, and skin inflammation, while promoting faster healing of lesions and preventing scarring. Neem’s ability to purify the blood and Turmeric’s potent anti-inflammatory effects make them invaluable components of Ayurvedic acne therapies. Likewise, Sandalwood’s cooling properties and Aloe Vera’s regenerative effects enhance the overall efficacy of Ayurvedic treatments. Moreover, the use of Mukhlepa (herbal face applications) and Shodhana Chikitsa (purification therapies) further strengthens Ayurvedic acne management. These therapies not only detoxify the body but also restore dosha balance, which is key to preventing the recurrence of acne. In conclusion, Ayurvedic approaches to acne treatment, based on centuries of traditional knowledge and supported by modern research, offer promising alternatives to conventional therapies. As interest in natural and alternative medicine grows globally, there is immense potential for integrating Ayurvedic treatments into mainstream skincare practices. However, more clinical studies and standardized formulations are needed to fully validate the effectiveness of these therapies and to optimize their application in modern dermatology.

REFERENCES:

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  2. Nand P, Drabu S, Gupta RK. A: In vitro and in vivo assessment of polyherbal topical gel formulation for the treatment of acne vulgaris. International Journal of Drug Delivery. 2012;4:434–42.
  3. Kumbhar MJ, Pawar MP, Pacharne MG, Walunj PK. Formulation and evaluation of polyherbal gel for treatment of acne. International Journal of Advanced Research in Science, Communication and Technology. 2022;965–74. Available from: http://dx.doi.org/10.48175/ijarsct-4760.
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  7. Suchitra P, Bhat DRV, Yadavannavar D. Venkatesh P: A bird eye view on tarunyapidika through ayurveda classic. WJPR. 2022;11:1690–700.
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  10. Verma A, Kumar B, Alam P, Singh V, Gupta SK. Rubia cordifolia – a review on pharmaconosy and phytochemistry. IJPSR. 2016;7(7):2720–31.
  11. Upadhyay A, Khanal H, Joshi RK. Ram Kishor Joshi: Case Report: Ayurvedic Management of Acne Vulgaris. Journal of Ayurveda. 2021;15.
  12. André Rolim Baby T, Batello Freire G, Marques P, Rijo F, Vieira Lima J, Carlos Monteiro De Carvalho J. Wagner Vidal Magalhães, Maria Valéria Robles Velasco and Ana Lucía Morocho-Jácome: Azadirachta indica (Neem) as a Potential Natural Active for Dermocosmetic and Topical Products: A Narrative Review. Cosmetics. 2022;9.
  13. Subapriya R, Nagini S. Medicinal properties of neem leaves: a review. Curr Med Chem Anticancer Agents. 2005;5(2):. doi:10.2174/1568011053174828.
  14. Dr. G, Mangal D. Avvinish Narine: Youvan pidika (acne vulgaris) and its management through ayurvedic principles (a review article). IJRMST. 2019;(8).
  15. Chakraborty S, Das A. Aparajita Das: A Classical Ayurveda Review on Haridra. AYUSHDHARA. 2020;7(1):47–55
  16. Sharifi-Rad J, Quispe C, Turgumbayeva A, Mertdinç Z, Tütüncü S, Elif Feyza Aydar B, et al. Elena Maria Varoni, Marcello Iriti and Daniela Calina. Z. Naturforsch: Santalum Genus: phytochemical constituents, biological activities and health promoting-effects. De Gruyter. 2023;78(1–2):9–25.
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  19. Borah, Biswas S. Ocimum sanctum, excellent source of phytochemicals. IJEAB. 2018;3(5).
  20. Nura Muhammad Umar T, Parumasivam N. Seok-Ming Toh: Phytochemical and pharmacological properties of Curcuma aromatica Salisb (wild turmeric). Journal of Applied Pharmaceutical Science. 2020;10(10):180–94.
  21. Gaire BP, Subedi L. Phytochemistry, pharmacology and medicinal properties of Phyllanthus emblica Linn. Chin J Integr Med. 2014; Available from: http://dx.doi.org/10.1007/s11655-014-1984-2.
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  23. Becker LC. Safety Assessment of Hamamelis virginiana (Witch Hazel)-Derived Ingredients as Used in Cosmetics. Cosmetic Ingredient Review Scientific Literature Review for Public Comment. 2018.
  24. Damle M. Glycyrrhiza glabra (Liquorice) - a potent medicinal herb. IJHM. 2014;2(2):132–6.
  25. Singh P, Singh R, Gupta LN, Kuma N. Neeraj Kuma: Lodhra- A Single Remedy For Different Ailments. IJPAB. 2015;6(1):1–7.
  26. Darshan P, Singh A, Agarwal A. Chemical constituents and medicinal properties of tinospora cordifolia(giloy). Int J Innovat Res Growth. 2022;11:83–7.
  27. Wei P, Zhao F, Wang Z, Wang Q, Chai X, Hou G, et al. Sesame (Sesamum indicum L.): A comprehensive review of nutritional value, phytochemical composition, health benefits, development of food, and industrial applications. Nutrients [Internet]. 2022;14(19):4079.
  28. Kumari I, Kaurav H, Chaudhary G. & Gitika Chaudhary: Myristica fragrans (Jaiphal): A Significant Medicinal Herbal Plant. Myristica fragrans. 2021;8:213–24.
  29. Manjula S, Bandara EL, Lee JE. Gotu Kola (Centella asiatica L.): An Under-utilized Herb. The Americas Journal of Plant Science and Biotechnology. 2011;5(2):20–31.
  30. Borah, Biswas S. Tulsi (Ocimum sanctum), excellent source of phytochemicals. IJEAB. 2018;3(5).
  31. Kotnala A, Verma K, Sharma A, Parashar S, Rathi B, Kumar R, et al. Indian Medicinal Plants for skin care and cosmeceuticals: A review. Journal of Biomedical and Therapeutic Sciences. 2019;6(2):24–60.
  32. azra J. Concept of beauty and Ayurveda medicine. J Clin Exp Dermatol Res [Internet]. 2013;04(03). Available from: http://dx.doi.org/10.4172/2155-9554.1000178.
  33. Manda K. An exploration into the diagnosis and management of neck pain by Ayurvedic practitioners in South Africa. Durban University of Technology; 2022.

Reference

  1. Sakthivel lakshmana Prabhu: Formulation and Evaluation Polyherbal face gel. In International Journal for Research Trends and Innovation. 2022;7(6):1635–7.
  2. Nand P, Drabu S, Gupta RK. A: In vitro and in vivo assessment of polyherbal topical gel formulation for the treatment of acne vulgaris. International Journal of Drug Delivery. 2012;4:434–42.
  3. Kumbhar MJ, Pawar MP, Pacharne MG, Walunj PK. Formulation and evaluation of polyherbal gel for treatment of acne. International Journal of Advanced Research in Science, Communication and Technology. 2022;965–74. Available from: http://dx.doi.org/10.48175/ijarsct-4760.
  4. Sinha P, Srivastava S, Mishra N, Yadav NP. New perspectives on antiacne plant drugs: contribution to modern therapeutics. Biomed Res Int. 2014;2014:301304. Available from: http://dx.doi.org/10.1155/2014/301304
  5. Raina D, Sharma S. Anil Sharma: Yauvana pidika-wsr to srotodushti. World Journal of Pharmaceutical Research. 9(13):112–26.
  6. Bharat Pawar P, Bhoir M. Chetan Manohar Patil, Divya Vilas Patil, Mrunali Balkrushna Patil. Riya Ravindra Patil: A Review on Polyherbal Gel Used in Treatment of Acne IJRPR. 2023;1123–8.
  7. Suchitra P, Bhat DRV, Yadavannavar D. Venkatesh P: A bird eye view on tarunyapidika through ayurveda classic. WJPR. 2022;11:1690–700.
  8. Sarvesh K, Satadru P, Maurya S, Kumar K. Kumar Dileep: Skin care in ayurveda: a literary review. International Research Journal of Pharmacy. 2013;4(3):1–3.
  9. Sachin Anil U. Sanjay Uttamrao Nipanikar: Review on Yuvanpidika Vis-A-Vis Acne Vulgaris. IJPPR. 2016;(5).
  10. Verma A, Kumar B, Alam P, Singh V, Gupta SK. Rubia cordifolia – a review on pharmaconosy and phytochemistry. IJPSR. 2016;7(7):2720–31.
  11. Upadhyay A, Khanal H, Joshi RK. Ram Kishor Joshi: Case Report: Ayurvedic Management of Acne Vulgaris. Journal of Ayurveda. 2021;15.
  12. André Rolim Baby T, Batello Freire G, Marques P, Rijo F, Vieira Lima J, Carlos Monteiro De Carvalho J. Wagner Vidal Magalhães, Maria Valéria Robles Velasco and Ana Lucía Morocho-Jácome: Azadirachta indica (Neem) as a Potential Natural Active for Dermocosmetic and Topical Products: A Narrative Review. Cosmetics. 2022;9.
  13. Subapriya R, Nagini S. Medicinal properties of neem leaves: a review. Curr Med Chem Anticancer Agents. 2005;5(2):. doi:10.2174/1568011053174828.
  14. Dr. G, Mangal D. Avvinish Narine: Youvan pidika (acne vulgaris) and its management through ayurvedic principles (a review article). IJRMST. 2019;(8).
  15. Chakraborty S, Das A. Aparajita Das: A Classical Ayurveda Review on Haridra. AYUSHDHARA. 2020;7(1):47–55
  16. Sharifi-Rad J, Quispe C, Turgumbayeva A, Mertdinç Z, Tütüncü S, Elif Feyza Aydar B, et al. Elena Maria Varoni, Marcello Iriti and Daniela Calina. Z. Naturforsch: Santalum Genus: phytochemical constituents, biological activities and health promoting-effects. De Gruyter. 2023;78(1–2):9–25.
  17. Nalimu J, Oloro I, Kahwa PE. Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox Florence. Future Journal of Pharmaceutical Sciences. 2021;7.
  18. Verma A, Kumar B, Alam P, Singh V, Gupta SK. Rubia cordifolia – a review on pharmaconosy and phytochemistry. IJPSR. 2016;7(7):2720–31.
  19. Borah, Biswas S. Ocimum sanctum, excellent source of phytochemicals. IJEAB. 2018;3(5).
  20. Nura Muhammad Umar T, Parumasivam N. Seok-Ming Toh: Phytochemical and pharmacological properties of Curcuma aromatica Salisb (wild turmeric). Journal of Applied Pharmaceutical Science. 2020;10(10):180–94.
  21. Gaire BP, Subedi L. Phytochemistry, pharmacology and medicinal properties of Phyllanthus emblica Linn. Chin J Integr Med. 2014; Available from: http://dx.doi.org/10.1007/s11655-014-1984-2.
  22. Touriño S, Lizárraga D, Carreras A, Lorenzo S, Ugartondo V, Mitjans M, et al. Highly Galloylated Tannin Fractions from Witch Hazel (HamamelisWirginiana) Bark: Electron Transfer Capacity. Vitro Antioxidant Activity, and Effects on Skin-Related Cells Chem Res Toxicol 2008. 2008;21.
  23. Becker LC. Safety Assessment of Hamamelis virginiana (Witch Hazel)-Derived Ingredients as Used in Cosmetics. Cosmetic Ingredient Review Scientific Literature Review for Public Comment. 2018.
  24. Damle M. Glycyrrhiza glabra (Liquorice) - a potent medicinal herb. IJHM. 2014;2(2):132–6.
  25. Singh P, Singh R, Gupta LN, Kuma N. Neeraj Kuma: Lodhra- A Single Remedy For Different Ailments. IJPAB. 2015;6(1):1–7.
  26. Darshan P, Singh A, Agarwal A. Chemical constituents and medicinal properties of tinospora cordifolia(giloy). Int J Innovat Res Growth. 2022;11:83–7.
  27. Wei P, Zhao F, Wang Z, Wang Q, Chai X, Hou G, et al. Sesame (Sesamum indicum L.): A comprehensive review of nutritional value, phytochemical composition, health benefits, development of food, and industrial applications. Nutrients [Internet]. 2022;14(19):4079.
  28. Kumari I, Kaurav H, Chaudhary G. & Gitika Chaudhary: Myristica fragrans (Jaiphal): A Significant Medicinal Herbal Plant. Myristica fragrans. 2021;8:213–24.
  29. Manjula S, Bandara EL, Lee JE. Gotu Kola (Centella asiatica L.): An Under-utilized Herb. The Americas Journal of Plant Science and Biotechnology. 2011;5(2):20–31.
  30. Borah, Biswas S. Tulsi (Ocimum sanctum), excellent source of phytochemicals. IJEAB. 2018;3(5).
  31. Kotnala A, Verma K, Sharma A, Parashar S, Rathi B, Kumar R, et al. Indian Medicinal Plants for skin care and cosmeceuticals: A review. Journal of Biomedical and Therapeutic Sciences. 2019;6(2):24–60.
  32. azra J. Concept of beauty and Ayurveda medicine. J Clin Exp Dermatol Res [Internet]. 2013;04(03). Available from: http://dx.doi.org/10.4172/2155-9554.1000178.
  33. Manda K. An exploration into the diagnosis and management of neck pain by Ayurvedic practitioners in South Africa. Durban University of Technology; 2022.

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Avinash Bichave
Corresponding author

Lokmanya Tilak institute of Pharmacy Kharghar Navimumbai

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Dhanashree kasar
Co-author

Lokmanya Tilak institute of Pharmacy Kharghar Navimumbai

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Shrutika Patil
Co-author

Lokmanya Tilak institute of Pharmacy Kharghar Navimumbai

Bichave Avinash, Kasar Dhanashree , Patil Shrutika, Ayurveda And Acne Treatment: A Comprehensive Review, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 10, 1682-1694. https://doi.org/10.5281/zenodo.14002164

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