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  • A Pharmacological Evaluation Of Antihistaminic And Anti Inflammatory Activity On O. Sanctum Leaves

  • 1PG Scholar, College of Pharmacy, Dr. A.P. J. Abdul Kalam University, Indore.
    2Professor, College of Pharmacy, Dr. A.P. J. Abdul Kalam University, Indore
    3Associate Professor, College of Pharmacy, Dr. A.P. J. Abdul Kalam University, Indor.
    4Professor and Principal, College of Pharmacy,Dr. A.P. J. Abdul Kalam University, Indore.

Abstract

The objective of the present study to a Pharmacological evaluation of antihistaminic and Anti-Inflammatory activity on O. sanctum leaves. In recent year there has been tremaendous increase in demand for herbal drugs because of its safety, efficacy and better therapeutic results. Due to its economic pricing as compared to synthetic or allopathic drugs, which have several therapeutic compilation sanctum leaves is also considered to be therapeutically important in traditional system of medicine. To study the A Pharmacological evaluation of antihistaminic and anti-Inflammatory activity on study the in vitro anti-inflammatory activity of the extract on sanctum Leaves Extraction of the plant material on O. sanctum Leave Conduction of the preliminary phytochemical screening and finding out the phytoconstituents present in the ethanolic extract of on O. sanctum Leaves Evaluation of the anti-asthmatic effect of O. sanctum Leaves In vivo methods Histamine aerosol induced bronchoconstriction in guinea pigs, Milk induced leukocytosis and eosinophil count, Ex vivo methods, Isolated guinea pig tracheal preparation, Evaluation of the Antihistaminic study of (on O. sanctum Leave In vitro methods Hydrogen peroxide scavenging assay, Reducing power assay Evaluation of the anti-inflammatory study of (on O. sanctum Leaves,In vitro methods Protein denaturation method, the rabbit red blood cell (RRBC) membrane stabilization method.

Keywords

Antihistaminic, Anti-Inflammatory, O. sanctum Leaves, Ethanolic Extract

Reference

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Photo
Laxmi Sirvi
Corresponding author

PG Scholar, College of Pharmacy, Dr. A.P. J. Abdul Kalam University, Indore.

Photo
Rajendra S. Bapna
Co-author

Professor, College of Pharmacy, Dr. A.P. J. Abdul Kalam University, Indore

Photo
Ragini Bundela
Co-author

Associate Professor, College of Pharmacy, Dr. A.P. J. Abdul Kalam University, Indore

Photo
Karunakar Shukla
Co-author

Professor and Principal, College of Pharmacy,Dr. A.P. J. Abdul Kalam University, Indore.

Reetesh Yadav, Shagun Upadhyay, Aman Agrawal, In Silico Studies - Molecular Docking Of Novel Alkaloids As Potential Candidates For Treatment Of Alzheimer Diseases, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 1, 738-751. https://doi.org/10.5281/zenodo.10579178

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