View Article

  • Revolutionary Advancements in Fast Dissolving Tablets: An In Depth Exploration
  • 1University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur-522 510, Andhra Pradesh, India.
    2Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chandramoulipuram, Chowdavaram, Guntur-522 019, Andhra Pradesh, India

Abstract

A novel drug delivery system plays a pivotal role in enhancing patient adherence to medication regimens. Among these innovative approaches, fast dissolving tablets (FDT’s) stand out as a particularly promising option. FDT’s offer a range of benefits, including precise dosing, ease of transport, streamlined manufacturing, robust physical and chemical stability, and they serve as an excellent alternative for both paediatric and geriatric patients. The formulation of FDT’s harnesses the advantages of both liquid and conventional tablet formulations, while also surpassing the merits of traditional dosage forms. In this comprehensive review, we delve into the advantages and limitations of FDT’s, the imperative need for their formulation, key formulation factors, the role of excipients, methodology, and critical evaluation parameters.

Keywords

Melting, Fast dissolving tablets, evaluation

Reference

  1. Kuchekar BS, Bhise SB and Arungam V. Design of Fast Dissolving Tablets. Indian J Pharm Edu 2005; 35:150. 
  2. Satinder Kakar, Ramandeep Singh, Alok Semwal.Transdermal drug delivery as a boon. Asian Pacific Journal of Health Sciences, 2014; 1(1): 13-25.
  3. Chang R. Guo X. Burnside, B. A. Couch R. Fast-Dissolving Tablets Pharmaceutical Technology  2000; 24(6):52-58. 
  4. Sastry SV, Nyshdham JR, Fix JA. Recent technologies advances in oral drug delivery: A review. Pharmaceutical Sciences and Technological Today 2001; 3:138-45. 
  5. Seager H. Drug-delivery products and the zydus fast- dissolving dosage form. Journal of Pharmacy and Pharmacology 1998; 50(4):375-382. 
  6. Hitesh Jagani, Ravi Patel, Pratik Upadyay, Jitendra Bhangale, Satish Kosalge. Fast Dissolving Tablets: Present and Future Prospectus. Journal of Advances in Pharmacy and Healthcare Research 2011: 4: 57-70.
  7. Hiremath JG, Shastry CS and Srinath MS. Pharmaceutical approaches of taste masking in oral dosage forms. Indian Drugs 2004; 41(5):253-257. 
  8. Sreenivas SA, Dandagi PM, Gadad AP, Godbloe AM,Hiremath SP, Mastiholimath VS. Orodispersible tablets: New-fangled drug delivery systems – A review. Indian Journal of Pharmaceutical Education and Research 2005; 39 (4)177-181. 
  9. Bradoo R. Fast Dissolving Drug Delivery Systems. JAMA India 2001; 4(10):27-31. 
  10. Mahapatra AK, Murthy PN, Sahoo J, Biswal S, Sahoo SK. Formulation design and optimization of mouth dissolving tablets of levocetrazine Hydrochloride using sublimation technique. Indian Journal of Pharmaceutical Education and Research 2008; 43(1): 39-45. 
  11. Gohel M, Patel M, Amin A, Agarwal R, Dave R and Bariya N. Formulation design and optimization of mouth dissolving tablets of nimesulide using vaccum drying technique. APPS Pharma Sci Tech 2004; 5:1-6.
  12. Panigrahi D, Baghel S, Mishra B. Mouth dissolving tablet: An overview of preparation and techniques, evaluation and patented technologies. Journal of pharmaceutics research 2005; 4:33-38. 
  13. Biradar SS et al. Fast dissolving drug delivery systems: a brief overview. The Internet Journal of Pharmacology 2006; 4(2). 
  14. Slowson M et al. What to do when patients cannot swallow their medications. Pharm. Times 1985: 51:90-96. 
  15. Chang RK et al. Fast-dissolving tablets. Pharmaceutical Technology 2000; 24(6):52- 58. 
  16. Lachmann L. et al. The theory and practice of Industrial Pharmacy. Varghese Publishing House, Bombay; 1990, p 293. 
  17. AvailablefromURL:http://www.ispub.com/ostia/index.php?Xmlfilepath=jounals/jjpharm/front.Xml.
  18. Reddy LH et al. Fast dissolving drug delivery systems: A review of the literature. Indian Journal of Pharmaceutical Sciences 2002; 64(4):331-336. 
  19. Indurwade NH et al. Novel approach – Fast dissolving tablets. Indian drugs 2002; 39(8):405-409. 
  20. Kuchekar BS et al. Mouth dissolving tablets: A novel drug delivery system. Pharma times 2003; 35:7-9. 
  21. Kumar A et al. A review on evaluation and formulation of fast dissolving tablets. International Journal of Drug Research and Technology 2011; 1(1):8-16. 
  22. Modi A et al. Formulation and evaluation of fast dissolving tablets of diclofenac sodium using different superdisintegrants by direct compression method. Pharmacia 2012: 1(3) 95-101. 
  23. Chang RK, Guo X, Burnside BA, Couch R. Fast dissolving tablets. Pharma Tech 2000; 24(6): 52-58.
  24. Kumari S, Visht S, Sharma PK., Yadav RK. Fast dissolving Drug delivery system: Review Article. Journal of Pharmacy Research 2010; 3(6):1444-1449. 
  25. Kumar Dinesh V, Sharma Ira, Sharma Vipin. A Comprehensive review on fast dissolving tablet technology. Journal of Applied Phamaceutical Science 2011; 01(05):50-58.
  26. Shaikh Siraj, Khirsagar RV, Quazi Aamer. Fast disintegrating tablets an overview of formulations and technologies. International Journal of Pharmacy and Pharmaceutical Sciences 2010; 2(3):9-11. 
  27. Hirani JJ, Rathod DA, Vadalia KR. Orally Disintegrat ing Tablets: A Review, Tropical Journal of Pharmaceut ical Research 2009; 8 (2): 161-172.
  28. Bhandari S, Mittapalli RK, Gannu R, Rao YM, Orodispersible tablet: An overview, Asian Journal of Pharmaceutics 2008; 2:2-11. 
  29. Reddy LH, Ghosh BR, Fast dissolving drug delivery systems: A review of the literature, Indian Journal of Pharmaceutical Sciences 2002; 64(4): 331-336. 
  30. Brown D, Orally disintegrating tablets: Taste over speed. Drug Delivery Technology 2001; 3 (6): 58-61. 
  31. Seager H. Drug-delivery products and Zydis Fast-dissolving dosage form. Journal of Pharmacy and Pharmacology 1998; 50: 375- 382. 
  32. Lies MC, Atherton AD, Copping NM. US Patent 5,188,825. 1993. 
  33. Carstensen JT. Pharmaceutics of Solids and Solid Dosage Forms. Wiley Interscience, New York, 1977; p 5-11. 
  34. Van Campen L, Zografi G, Carstensen JT. An approach to the evaluation of hygroscopicity for pharmaceutical solids. International Journal of Pharmaceutics 1980; 5:1–18.
  35. Chang RK, Guo X, Burnside BA, Couch RA. Fast-dissolving tablets. Pharmaceutical Technology North America 2000; 24:52–58. 
  36. Sharma S. New Generation of Tablet: Fast Dissolving Tablet. Latest Reviews. Pharmainfo.Net 2008; 6(1). 
  37. Kumari S, Visht S, Sharma PK, Yadav RK. Fast dissolving Drug delivery system: Review Article. Journal of Pharmacy Research 2010; 3(6):1444-1449. 
  38. Pebley WS, Jager NE. US Patent No.5, 298261,5-17.1994. 
  39. Reddy LH, Ghosh BR, Fast dissolving drug delivery systems: A review of the literature, Indian Journal of Pharmaceutical Sciences 2002; 64(4):331-336. 
  40. Hirani JJ, Rathod DA, Vadalia KR. Orally Disintegrating Tablets: A Review. Tropical Journal of Pharmaceutical Research 2009; 8 (2):161-172.
  41. Sehgal P et al. Fast dissolving tablets: a new venture in drug delivery. American Journal of PharmTech Research 2012; 2(4):252-279. 
  42. Mohanachandran PS, Sindhumol PG, Kiran TS. Superdisintegrants: An overview, International Journal of Pharmaceutical Sciences Review and Research 2011; 6:105- 109. 
  43. Sharma S. New Generation of Tablet: Fast Dissolving Tablet. Latest Reviews. Pharmainfo.Net 2008; 6(1). 
  44. Kumari S, Visht S, Sharma PK, Yadav RK. Fast dissolving Drug delivery system: Review Article. Journal of Pharmacy Research 2010; 3(6): 1444-1449. 
  45. Kumaresan C. Orally Disintegrating Tablet - Mouth dissolving, Sweet Taste and Target Release Profile. Pharmaceutical review 2008; 6. 
  46. Deshmukh VN. Mouth Dissolving Drug Delivery System: A Review. International Journal of Pharm Tech Research 2012; 4(1) 412-421.
  47. Kumari S, Visht S, Sharma PK, Yadav RK. Fast dissolving Drug delivery system: Review Article; Journal of Pharmacy Research 2010; 3(6):1444-1449. 
  48. Johnson JR, Wang LH, Gordon MS, Chowhan ZT. Effect of formulation solubility and hygroscopicity on disintegrating efficiency in tablets prepared by wet granulation. Journal of Pharmaceutical Sciences 1991; 80:469–71. 
  49. Billany MR, Aulton ME. Pharmaceutics; The science of Dosage form Design, New York: Churchill Livingstone, International Edition, 1996; p 263. 
  50. Catania JS, Johnson AD. U. S. Patent 5633006. 1997. 
  51. Nelson SL. U.S. Patent 5766622.1998.
  52. Eby III, Georage A. U.S. Patent 5002970. 1991. 
  53. Pandya HB, Callan TP. U.S. Patent 5, 837, 286. 1998. 
  54. Patel S Taher, Sengupta Mukul. Fast Dissolving Tablet Technology – A Review. World Journal of Pharmacy and Pharmaceutical Sciences 2013; 2 (2): 485-508. 
  55. Gohel M, Patel M, Amin A, Agrawal R, Dave R, Bariya N. Formulation Design and Optimization of Mouth Dissolve Tablets of Nimesulide Using Vacuum Drying Technique. AAPS Pharm Sci Tech 2004; 5(3):36-40. 
  56. Ford J. The current status of solid dispersion. Pharmaceutica Acta Helvetiae 1986; 61:69– 88. 
  57. Dobetti L. Fast melting tablets: Developments and technologies. Pharm Technol Drug Deliv 2001 ;(Suppl):44–50. 
  58. Tanmoy Ghosh, Amitava Ghosh and Devi Prasad. A Review on new generation orodispersible tablets and its future prospective. International Journal of Pharmacy and Pharmaceutical Sciences 2011; 3(1):1-7. 
  59. Abdul Sayeed, Mohd. Hamed Mohinuddin. Mouth dissolving tablets: An overview. Int. Journal of Research in Pharmaceutical and Biomedical Sciences 2011; 2(3): 959-970. 
  60. Yang S, Fu Y, Jeong SH, Park K. Applications of poly (acrylic acid) Superporous hydrogel microparticles as a superdisintegrants in fast disintegrating tablets. J Pharmacy and Pharmacology 2004; 56: 429-36. 
  61. Ozeki T et al. Design of rapidly disintegrating oral tablets using acid treated yeast cell wall: A technical note. APPS Pharmasci Tech 2003; 4(4):561-564. 
  62. Giunchedi P, Conti B, Genta I, Conte U, Puglisi G. Emulsion spray drying for the preparation of albumin-loaded PLGA microspheres. Drug Development and Indian Pharmacy 2001; 27:745–750. 
  63. Alysson LR, Wanderley PO. Spray drying conditions and encapsulating composition effects on formation and properties of sodium diclofenac microparticles. Powder Technol 2007; 171:7–14. 
  64. Donald LW. Handbook of Pharmaceutical Controlled Release Technology, Marcel Dekker Inc, New York:; 2005, p 112–113. 
  65. Lieberman HA, Lachman L, Schwartz JB. Pharmaceutical Dosage Forms: Tablets, New York: Marcel Dekker Inc; 2005, p 187. 
  66. C Kumaresan. Orally Disintegrating Tablet - Mouth dissolving, Sweet Taste, and Target Release Profile; Pharmaceutical review 2008; 6(5):1–10. 
  67. Kuno Y, Kojima M, Ando S, Nakagami H. Evaluation of rapidly disintegrating tablets manufactured by phase transition of sugar alcohols. Journal of Controlled Release 2005; 105(1-2): 16-22. 
  68. Narang A., Shrivastava A. Melt extrusion solid dispersion technique. Drug Development and Indian Pharmacy. 2002; 26(8);111-115. 
  69. Dong Y, Kulkarni R, Behme R J, Kotiyan PN. Effect of the melt granulation technique on the dissolution characteristics of griseofulvin. International Journal of Pharmaceutics 2007; 329 (1-2):72-80. 
  70. Gupta A, Mishra AK, Gupta V, Bansal P, Singh R and Singh AK. Recent Trends of Fast Dissolving Tablet – An Overview Formulation Technology. International Journal of Pharmaceutical & Biological Archives 2010; 1(1):1-10. 
  71. Bandari S, Mittapalli RK, Gannu R, Rao YM. Orodispersible tablets: An overview. Asian Journal of Pharmaceutics 2008; 2(1):2-11. 
  72. Deshmukh Keshav Ram et al. A review on mouth dissolving tablet techniques. International Journal of Research in Ayurveda and Pharmacy 2001; 2(1): 66-74. 
  73. Tejvir Kaur et al. Mouth dissolving tablets: A Novel approach to drug delivery. Int Journal of Current Pharnaceutical Research 2011; 3(1): 1-7. 
  74. Takaishi Y, Mizumoto T, Masuda Y. EP patent 1,323,417 (2006). 
  75. Availablefrom:http://www.phamacast.com/p atents100/Yr2004/May2004/051104/673378 1_Fast Dissolving 051104.htm. 
  76. Seager H. Drug-deliver Products and the Zydis Fast-dissolving Dosage Form Journal of Pharmacy and Pharmacology 1998; 50: 375- 382. 
  77. Sreenivas SA, Dandagi PM, Gadad AP, Godbole AM, Hiremath SP, Mastiholimath VSM and Bhagwati ST. Orodispersible tablets: New fangled drug delivery system: A review. ndian Journal of Pharmaceutical Education and Research 2005; 39(4):177-181. 
  78. Fu Y, Yang S, Jeong SH,Kimura S, Park K. Orally fast disintegrating tablets: Developments, technologies, taste-masking and clinical studies. Critical reviews in therapeutic drug carrier systems 2004; 21(6):433-76. 
  79. Morita Y, Tsushima Y, Yasui M, Termoz R, Ajioka J, Takayama K. Evaluation of the disintegration time of rapidly disintegrating tablets via a Novel method utilizing a CCD camera. Chemical & pharmaceutical bulletin 2002; 50(9): 1181-1186. 
  80. Shangraw R., Mitrevej A, Shah M. A new era of tablet disintegrants. Pharma Tech 1980; 4(10): 49-57.
  81. Kaushik D, Dureja H, Saini TR, Formulation and evaluation of olanzapine mouth dissolving tablet by effervescent formulation approach. Indian Drugs 2004; 41: 410–412. 
  82. Kaushik D, Dureja H, Saini TR, Orally disintegrating tablets: An overview of melt in mouth tablet technologies and techniques. Tablets Capsules 2004; 2: 30-36. 
  83. Gole D, Savall T, fu GL, Dale W, Paul K, Davies JD. US Patent application 20050036977, (2005). 
  84. Iles MC, Atherton AD, Copping NM. US Patent 5,188,825, (1993). 
  85. Gupta A. Recent Trends of Fast Dissolving Tablet-An Overview of Formulation Technology. International Journal of Pharmaceutical & Biological Archive 2010; 1(1): 1-10. 
  86. Kovacic M., Milovac J, Cvelbar P, Stalc A, Trost Z, Kopitar Z, Kofler B, Nikolic V, Lampret M, Lippai M. US Patent 5,069,910. 1991. 
  87. Milovac J., Kovacic M., Kopitar Z., UrbancicSmerkolj J., Lenardic A., Zorz M., Kofler B., Vene-Mozina A., Nikolic V., Lampret M. US Patent 5,047,247. 1991. 
  88. Pather SI, Khankari RK, Moe DV. OraSolv and DuraSolv: Efficient technologies for the production of orally disintegrating tablets. Drugs and the Pharmaceutical Sciences 2003; 126:203-16. 
  89. Ohta M., Hayakawa E., Ito K., Tokuno S., Morimoto K., Watanabe V. W.O. Patent 9, 747,287. 1997. 
  90. Yourong F., Shicheng Y, Seong HJ, Kimura S, Park K, Orally Fast Disintegrating Tablets: Developments, Technologies, Taste-Masking and Clinical Studies Critical Reviews in Therapeutic Drug Carrier Systems 2004; 21:6: 433–475. 
  91. Sayeed A., Mohiuddin M.H., Mouth dissolving tablets: An Overview. International Journal of Research in Pharmaceutical and Biomedical Sciences 2011; 2(3): 959-970. 
  92. Fu Y, Yang S, Jeong SH,Kimura S, Park K. Orally fast disintegrating tablets: Developments, technologies, taste-masking and clinical studies. Critical reviews in therapeutic drug carrier systems 2004; 21(6): 433-476. 
  93. Yadav G, Kapoor A, Bhargava S. Fast dissolving tablets recent advantages: A review. International Journal of Pharma Sciences and Research 2012; 3(3): 728 -736. 
  94. Mehta K, Garala K, Basu B, Bhalodia R, Joshi B, Charyulu RN. An emerging trend in oral drug delivery technology: Rapid disintegrating tablets 2010; 2(10): 318-329. 
  95. Patel SS, Patel MS, Patel NM. Flowability testing of directly compressible excipients according to british pharmacopoeia. Journal of Pharmaceutical Research 2009; 8: 66 -69. 
  96. Javier OM, Hong M, Aubey MG, Jason TM. Orally Disintegrating Tablets using starch and fructose. Pharmaceutical Technology 2010: 92-99. 
  97. Sharma D, Kumar D, Singh M, Singh G, Rathore MS. Fast disintegrating tablets: a new era in novel drug delivery system and new market opportunities. Journal of Drug Delivery & Therapeutics 2012; 2(3): 74-86. 
  98. Deshmukh VN. Mouth Dissolving Drug Delivery System: A Review. International Journal of Pharm Tech Research 2012; 4(1): 412-421. 
  99. Patel S Taher, Sengupta Mukul. Fast Dissolving Tablet Technology – A Review. World Journal of Pharmacy and Pharmaceutical Sciences 2013; 2(2):485-508. 
  100. Bi Y. Preparation and evaluation of a compressed tablet rapidly disintegrating in the oral cavity. Chemical and Pharmaceutical Bulletin 1996; 44: 2121-2127. 
  101. Jeong SH, Takaishi Y, Park K. Material properties for making fast dissolving tablets by a compression method. Journal of Materials Chemistry 2008; 18: 3527–3535. 
  102. Kumar S, Gupta SK, Sharma PK. A Review on Recent Trends in Oral Drug Delivery-Fast Dissolving Formulation Technology. Advances in Biological Res 2012; 6 (1): 06-13. 
  103. Lalla JK, Mamania HM. Fast dissolving rofecoxib tablets. Indian Journal of Pharmaceutical Sciences 2004; 59(4):23-26. 
  104. 1Bhowmik D et al. Fast Dissolving Tablet: An Overview. Journal of Chemical and Pharmaceutical Research 2009; 1:163-177. 
  105. Mahaveer Pr. Khinchi. Orally disintegrating tablets: A future prospectus. International Journal of Pharma and Bio Sciences 2010; 71-79. 
  106. Hindustan Abdul Ahad, Chitta Suresh Kumar, Kishore Kumar Reddy B, Anil Kumar B, Chandra Sekhar A, Sushma K, Sairam T, Sivaji S. A Novel Technique in Formulation and Evaluation of Mouth Dissolving Nimesulide Tablets. Journal of Advanced Pharmaceutical Research 2010; 1(2): 101-107. 
  107. Mohanachandran PR, Krishnamohan PR, Fels Saju, Bini.KB, Beenu B, Shalina KK. Formulation and evaluation of mouth dispersible tablets of amlodipine. International Journal of Applied Pharmaceutics 2010; 2 (3): 1-6. 
  108. Suresh B, Rajendar KM, Ramesh G, Yamsani MR. Orodispersible tablets: An overview. Asian Journal of Pharmaceutical Sciences 2008; 2: 2–11. 
  109. Bhupendra G. Prajapati, and Satish N Patel. Formulation, evaluation and optimization of orally disintegrating tablet of cinnarizine. E-Journal of Science & Technology 2010; 5(5): 9-21. 
  110. Chaudhari PD, Chaudhari SP, Kolhe SR, Dave KV, More DM. Formulation and evaluation of fast dissolving tablets of famotidine. Indian Drugs 2005; 42: 641-649. 
  111. Nandgude TD, Saifee M, Bhise KS. Formulation and evaluation of fast disintegrating tablets of diphenhydramine tannate. Asian Journal of Pharmaceutical Science 2006; 1(1):41-45. 
  112. Kannuri R, Challa T, Chamarthi H. Taste masking and evaluation methods for orodispersible tablets. International Journal of Pharmaceutical Industrial Researh 2011;1(3):201-210. 
  113. Yadav G, Kapoor A, Bhargava S. Fast dissolving tablets recent advantages: a review. Internation Journal of Pharmaceutical Science and Research 2012; 3(3): 728-736.
  114. Chaudhari PD., Chaudhari SP., Lanke SD. and Patel N. Formulation and in vitro evaluation of teste masked orodispersible dosage form of Levocetirizine dihydrochloride. Indian Journal of Pharmacuitical Education and Research 2007; 41(4):319-327.

Photo
Shabana Parveen
Corresponding author

University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur-522 510, Andhra Pradesh, India.

Photo
A. Ramu
Co-author

Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chandramoulipuram, Chowdavaram, Guntur-522 019, Andhra Pradesh, India

Shabana Parveen, A. Ramu, Revolutionary Advancements in Fast Dissolving Tablets: An In-Depth Exploration, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 9, 427-446. https://doi.org/10.5281/zenodo.8381942

More related articles
Klinefelter Syndrome: Understanding The Genetic Et...
R. VIGNESWARAN, NATARAJAN P, KODISHWARAN R, PRAKASH M, MONISHA V,...
A Novel Simultaneous Estimation Of Ramipril And Ol...
Priti R. Kale , Vishal Babar, Ashish B. jadhav , ...
A Comparative Study Of Drug Master File Regulation...
Jenilkumar J. Diyora, Vinit Movaliya, Maitreyi Zaveri, ...
An Overview On Hyperthyroidism ...
Naman Kishor Gandhi, Sneha S Kanase, Tejas S Bagmar, Aditya D Dhiwar, Abhishek A Choughule , Gaurav ...
Green Synthesis of Zinc Oxide Nano-particles and their Applications...
Shruti S. Jadhav, Dr. Mohini A. Salunke, Dr. B.S Wakure, Mohammad Zishan Ibrahim, ...
A Review On Ultrasound in pharmaceutics ...
Dipti Muntode , Rajeshree Khandre, ...
Related Articles
Formulation And Evaluation Of Herbal Medicated Bath Bomb...
Jayesh Maruti Shinde , Nilam B. Khairnar , Vivek N. Patil, Aarti B. Sansare, Shruti A. Pitrubhakta ,...
Solid Lipid Nano Particle - A Therapeutic Approach In Cancer Treatment ...
Jamuna Mekaliya, Dharmesh Sisodiya , Kamlesh Dhashora, ...
Enhancing Patient Care With AI Chatbots And Virtual Assistants...
Asma Shaikh , Haritha CK, Arina Mullick, Varun Gadia, ...
Klinefelter Syndrome: Understanding The Genetic Etiology, Pathogenesis Diagnosis...
R. VIGNESWARAN, NATARAJAN P, KODISHWARAN R, PRAKASH M, MONISHA V, SINEHA M, KALYANI M, SAMPATH RAJA ...
More related articles
Klinefelter Syndrome: Understanding The Genetic Etiology, Pathogenesis Diagnosis...
R. VIGNESWARAN, NATARAJAN P, KODISHWARAN R, PRAKASH M, MONISHA V, SINEHA M, KALYANI M, SAMPATH RAJA ...
A Comparative Study Of Drug Master File Regulation In Brazil, Malaysia And Russi...
Jenilkumar J. Diyora, Vinit Movaliya, Maitreyi Zaveri, ...
Klinefelter Syndrome: Understanding The Genetic Etiology, Pathogenesis Diagnosis...
R. VIGNESWARAN, NATARAJAN P, KODISHWARAN R, PRAKASH M, MONISHA V, SINEHA M, KALYANI M, SAMPATH RAJA ...
A Comparative Study Of Drug Master File Regulation In Brazil, Malaysia And Russi...
Jenilkumar J. Diyora, Vinit Movaliya, Maitreyi Zaveri, ...