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SGRS College Of Pharmacy Saswad.
This review examines the formulation and potential therapeutic benefits of an Ayurvedic herbal powder designed to treat conjunctivitis, an eye condition characterized by inflammation of the conjunctiva, typically caused by infections, allergens, or irritants. 1Conjunctivitis is commonly associated with symptoms such as redness, itching, discharge, and swelling, and if left untreated, may lead to complications like keratitis or vision impairment. The herbal powder, created from a blend of seven medicinal herbs, aims to provide a natural and safer alternative to conventional treatments, minimizing the side effects commonly associated with synthetic drugs. The review explores the pharmacological actions of key ingredients, including anti-inflammatory, antimicrobial, and antioxidant properties, and how these compounds work synergistically to target the root causes of conjunctivitis. The formulation's preparation process, including grinding, sieving, and mixing, is analyzed to ensure consistency and quality. While the study presents a detailed approach to the formulation, this review suggests areas for improvement, such as the need for clinical trials to validate efficacy, comparative studies with existing treatments, and enhanced exploration of the molecular mechanisms at play. Emphasizing the holistic healing potential of the formulation, the review encourages further research into its safety, effectiveness, and possible improvements for broader application in treating conjunctivitis.
The above review focuses on a study that investigates the preparation of an Ayurvedic herbal powder designed to treat conjunctivitis. Conjunctivitis is a common eye condition characterized by the inflammation of the conjunctiva, which can be caused by various factors such as infections (viral or bacterial), allergens, irritants, or chemical exposure. The symptoms of conjunctivitis typically include redness, itching, swelling, discharge, and tearing. If untreated, it can lead to more severe complications such as keratitis or even permanent vision impairment.
Key Points from the Review:
The review delves into the pharmacological properties of these herbs:
Areas for Further Exploration:
Conjunctivitis, commonly known as "pink eye," is an eye condition characterized by inflammation of the conjunctiva, the thin, transparent membrane that covers the white part of the eyeball and the inside of the eyelids. The condition can be caused by a variety of factors, including infections (bacterial, viral), allergies, irritants, or exposure to chemicals. Here's an overview of the types of conjunctivitis, their causes, symptoms, and how they affect individuals:14
1. Viral Conjunctivitis8
Cause:
Viral conjunctivitis is most often caused by adenoviruses but can also be caused by other viruses, including those responsible for the common cold (e.g., rhinoviruses). It is highly contagious, often spreading in environments like schools or households.
Symptoms:
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Figure: - Images of different types of Conjunctivits and Red and Inflammed Eyes 1,14
2. Bacterial Conjunctivitis10
Cause:
Bacterial conjunctivitis is typically caused by bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, or Haemophilus influenzae. It can result from direct contact with an infected person, contaminated surfaces, or poor hygiene practices (e.g., touching the eyes with unclean hands).1
Symptoms:
3. Allergic Conjunctivitis7,9
Cause:
Allergic conjunctivitis is triggered by allergens like pollen, dust mites, pet dander, or mold. It is not caused by infections and is common in people with other allergic conditions, such as hay fever or asthma.1
Symptoms:
4. Chemical/Irritant Conjunctivitis12
Cause:
Chemical conjunctivitis occurs when the eye is exposed to irritants such as smoke, chlorine in swimming pools, pollution, or household chemicals like cleaning products. It can also result from overuse of contact lenses or certain medications that irritate the eye.
Symptoms:
5. Neonatal Conjunctivitis11
Cause:
Neonatal conjunctivitis occurs in newborns and is often caused by infections acquired during birth, such as Chlamydia trachomatis, Neisseria gonorrhoeae, or from exposure to chemicals in the delivery process.
Symptoms:
6. Chronic Conjunctivitis13
Cause:
Chronic conjunctivitis may occur due to long-term exposure to irritants, underlying systemic conditions like dry eye disease or autoimmune disorders (e.g., rheumatoid arthritis), or persistent infections.
Symptoms:
1. Haritaki (Terminalia chebula)24
2. Bibhitaki (Terminalia bellerica)16,26
3. Amalaki (Emblica officinalis)17
4. Harida (Curcuma longa)25,27
5. Neem (Azadirachta indica)20,27
6. Sirish (Albizia lebbeck)16
7. Ashwagandha (Withania somnifera)18
8.Kesar (Crocus sativus)19
Saffron is beneficial for improving vision clarity and reducing the risk of cataracts. Its soothing properties help alleviate eye irritation and discomfort, making it effective in treating eye fatigue and general discomfort.
9. Brahmi (Bacopa monnieri)22
Brahmi is known for its cognitive-enhancing properties but is also highly beneficial for eye health.
Brahmi helps improve vision by reducing strain and tension in the eyes. It also has anti-inflammatory and antioxidant properties that protect the eyes from age-related degeneration, making it a great herb for maintaining long-term eye health.
10. Gokshura (Tribulus terrestris)23
Gokshura is traditionally used to support the health of the urinary and reproductive systems but also offers benefits for the eyes.
It helps improve vision, particularly in cases of blurry or dim eyesight, by boosting circulation to the eyes and supporting overall eye health. It’s especially helpful for those experiencing diminishing vision due to aging.
12. Vidarikand (Pueraria tuberosa)15
Vidarikand is known for its rejuvenating properties and is commonly used in Ayurvedic medicine to promote vitality.
Vidarikand supports vision, particularly in cases of eye fatigue and aging, and promotes overall eye health by nourishing the tissues of the eyes.
13. Chandana (Sandalwood - Santalum album)21
Sandalwood has cooling and soothing properties, making it a calming herb.
Sandalwood is often used as a soothing remedy for eye irritation and redness, especially in the case of heat-induced conditions like conjunctivitis. It helps reduce inflammation and calm the discomfort in the eyes.
14. Kachnar (Bauhinia variegata)27
Kachnar is known for its detoxifying and anti-inflammatory properties, which are beneficial for overall health.
Kachnar can be used to reduce swelling and inflammation around the eyes. It is believed to support the treatment of eye infections and reduce the discomfort caused by conditions like conjunctivitis or other eye inflammations.
15. Yastimadhu (Glycyrrhiza glabra)
Licorice, or Yastimadhu, is well known for its soothing and anti-inflammatory properties.
It helps in treating dry eyes and reducing irritation. Yastimadhu is particularly helpful in reducing symptoms of conjunctivitis and other inflammatory eye conditions, providing comfort and relief.
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Figure: - Different Herbs Used for Common Eye Problems. [2]
16. Manjistha (Rubia cordifolia)
Manjistha is a powerful detoxifying herb that helps purify the blood.
It supports eye health by improving blood circulation to the eyes, which is important for preventing conditions like cataracts and improving overall vision. Its detoxifying properties contribute to the healing of eye infections and irritation.
17. Anantmool (Indian Sarsaparilla - Hemidesmus indicus)3,4
Anantmool is known for its cooling, detoxifying, and anti-inflammatory properties.
Anantmool helps soothe the eyes and relieve symptoms associated with eye inflammation and irritation. It is especially beneficial for conditions like eye redness, swelling, and general discomfort caused by inflammation or infections.
CONCLUSION: -
In conclusion, this review underscores the potential of an Ayurvedic herbal powder formulation as a promising alternative to conventional treatments for conjunctivitis. By leveraging a blend of seven potent medicinal herbs, the formulation aims to address the root causes of conjunctivitis, including inflammation, microbial infections, and oxidative stress. The herbs selected—such as Haritaki, Bibhitaki, Amalaki, Neem, and Ashwagandha—bring forth a diverse range of therapeutic actions, including anti-inflammatory, antimicrobial, antioxidant, and detoxifying properties, which synergistically support eye health and aid in the healing of eye infections. Despite its promising formulation, the review highlights the need for further research to validate the efficacy and safety of the herbal powder. Clinical trials, comparative studies with existing synthetic treatments, and a deeper exploration of the molecular mechanisms at play are essential to strengthen the scientific foundation of the formulation. Additionally, safety testing, especially for individuals with allergies or sensitivities, is crucial to ensure its broad applicability. The review emphasizes the holistic healing potential of Ayurvedic herbs and encourages the continued investigation of their therapeutic benefits in the treatment of conjunctivitis. With further studies and advancements, this formulation could offer a safer, natural, and effective treatment option for conjunctivitis, reducing reliance on synthetic drugs and minimizing their associated side effects.
REFERENCES
Srushti Phadtare*, Sakshi Yadav, Vansh Wagh, Pradyna Yadav, Shreya Yadav, Sanket Wankhede, Review on Common Herbs Used For Conjunctivitis & Other Common Eye Problems, Int. J. of Pharm. Sci., 2025, Vol 3, Issue 5, 782-791 https://doi.org/10.5281/zenodo.15342964
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