View Article

Abstract

A plant is a source of natural remedies. It is a huge source of retinoid substances still some plants still need to be exposed for their quality uses. This review led to a full-length study of Tinospora cordifolia. Giloy is an essential herb that can be used to treat a wide range of illnesses. This plant, also known by its common names Guduchi, Amrita, and Amritvali, is a member of the Menispermaceae subfamily (family). glycosides, steroids, lactones, sesquiterpenoids, aliphatic compounds, lignin, and other various substances are typically found in this plant... India's Tinospora Cordifolia is a deciduous hiking/climbing plant used in Ayurvedic ethnomedicine. Tinofora cordifolia is a medicinal plant that has numerous therapeutic uses in the Ayurvedic and Unani medical systems. Tinospora cordifolia shows antioxidant activity, antidiabetic activity, anti-malarial activity, antibacterial activity, anti-fungal activity, anti-stress activity, hypolipidemic effect, hepatic disorder, anti-cancer, HIV potential, anti-osteoporotic effect, anti-toxic effect, wound healing, and immunomodulatory activity, the current review emphasizes the pharmacological importance. daily because, in contrast to allopathic drugs, they have a higher pharmacological reaction and no aspect (side effect) effect:). It has been used to treat a variety of illnesses, including diabetes, leprosy, fever, urinary issues, dysentery, and skin conditions.

Keywords

Menispermaceae, Guduchi, bioactive substance, pharmacological activity, and Tinospora cordifolia

Reference

  1. Abhimanyu Sharma, Asmitha Gupta, Sakshi Singh Amla Batra; Tinospora cordifolia (Willd.) Hook. F. & Thomson- A plant with immense economic potential; J.Chem. Pharm. Res., 2010, 2(5):327-333.
  2. https://www.researchgate.net/figure/Morphology-of-Tinospora-cordifolia-A-steam-B-root-C-leaves-D-flower-E-fruit-F-seed_fig1_335771772
  3. Amandeep Singh1, Nisha A Bhatt2 , Abhineskar Sagar3* , Amartya Kumar3 , Abhay Goswami3 MEDICINAL USES OF GILOY:A REVIEW.
  4. Manoj Kumar Sarangi1*, Shashank Soni1 A Review on Giloy: The Magic Herb
  5. M.Q.I. Khuda, A. Khaleque, N. Ray, Tinospora cordifolia constituents of plants fresh from the field, Sci. Res. 1 (1964) 177–183.
  6. J.B. Hanuman, R.K. Bhatt, B.K. Sabata, A diterpenoid furanolactone from Tinospora cordifolia, Phytochemistry 25 (1986) 1677–1680.
  7. R.K. Bhatt, J.B. Hanuman, B.K. Sabata, A new clerodane derivative from Tinospora cordifolia, Phytochemistry 27 (1988) 1212–1216.
  8. J.B. Hanuman, R.K. Bhatt, B. Sabata, A clerodane furano-diterpene from Tinospora cordifolia, J. Nat. Prod. 51 (1988) 197–201.
  9. R.K. Bhatt, B.K. Sabata, A furanoid diterpene glucoside from Tinospora cordifolia, Phytochemistry 28 (1989) 2419–2422.
  10. M.A. Khan, I.A. Gray, P.G. Waterman, Tinosporaside an 18-norclerodane glucoside from Tinospora cordifolia, Phytochemistry 28 (1989) 273–275
  11. V.D. Gangan, P.P. Arjun, T. Sipahimalani, A. Banerji, A. Cardifolisides, C. B, Norditerpene furon glucoside from Tinospora cordifolia, Phytochemistry 37 (1994) 781–786.
  12. R. Maurya, S.S. Handa, Tinocordifolin, a sesquiterpene from Tinospora cordifolia, Phytochemistry 44 (1998) 1343–1345.
  13. V.D. Gangan, P.P. Arjun, A.T. Sipahimalani, A. Banerji, Norditerpene furon glucoside from Tinospora cordifolia, Phytochemistry 39 (1995) 1139–1142.
  14. V. Wazir, R. Maurya, R.S. Kapil, A clerodane furano diterpene glucoside from Tinospora cordifolia, Phytochemistry 38 (1995) 447–449.
  15. V.D. Gagan, P. Pradhan, A.T. Sipahimalan, A. Banerji, F. Palmatosides C, Diterpene furan glucosides from Tinospora cordifolia-structural elucidation by 2D NMR spectroscopy, Indian J. Chem. 35B (1996) 630–634.
  16. N. Choudhary, M.B. Siddiqui, S. Azmat, S. Khatoon, Tinospora cordifolia: ethnobotany, phytopharmacology, and phytochemistry aspects, IJPSR 4 (2013) 891. [38] N.G. Bisset, J. Nwaiwu, Quaternary alkaloids of Tinospora species, Planta Med. 48 (1983) 275–279.
  17. V.R. Mahajan, C.I. Jolly, K.M. Kundnani, A new hypoglycaemic agent from Tinospora cordifolia, Indian Drugs 23 (1985) 119–120.
  18. A.K. Pathak, A.K. Agarwal, D.C. Jain, R.P. Sharma, O.W. Howarth, NMR studies of 20 hydroxyecdysones, a steroid isolated from Tinospora cordifolia, Indian J. Chem. 34 (1995) 674–676.
  19. J.B. Hanuman, A.K. Mishra, B. Sabata, A natural phenolic lignan from Tinospora cordifolia Miers, J. Chem. Soc. (1986) 1181–1185.
  20. A.R. Kidwai, K.C. Salooja, V.N. Sharma, S. Siddiqui, Chemical examination of Tinospora cordifolia, J. Sci. Indian Res. 8 (1949) 115–118.
  21. A.K. Pathak, D.C. Jain, P.R. Sharma, Chemistry and biological activities of the genus Tinospora, Int. J. Pharmacogn. 33 (1995) 277–287
  22. M.Q. Khuda, A. Khaleque, K.A. Basar, M.A. Rouf, M.A. Khan, N. Roy, Studies on Tinospora cordifolia II: isolation of tinosporine, tinosporic acid and tinosporol from the fresh creeper, Sci. Res. 3 (1966) 9–12
  23. A. Khaleque, M.A.W. Maith, M.S. Huq, K.A. Tinospora cordifolia III, Isolation of tinosporine, heptacosanol, ß sitosterol, Pakistan J . Sci. Industry Res. 14 (1971) 481–483.
  24. R. Maurya, V. Wazir, A. Tyagi, R.S. Kapil, Clerodane diterpene from Tinospora cordifolia, Phytochemistry 38 (1995) 659–661
  25. P. Pradhan, V.D. Gangan, A.T. Sipahimalani, A. Banerji, Two phytoecdysones from Tinospora cordifolia: structural assignment by 2D NMR spectroscopy, Indian J. Chem. 36B (1997) 958–962.
  26. G. Chintalwar, A. Jain, A. Sipahimalani, A. Banerji, P. Sumariwalla, R. Ramakrishnan, K. Sainis, An Immunologically active arabinogalactan from Tinospora cordifolia, Phytochemistry 52 (1999) 1089–1093.
  27. A. Khaleque, M.A.W. Maith, M.S. Huq, B. K Abul, Tinospora cordifolia IV. Isolation of octacosanol, ß sitosterol and three other compounds tinosporine, cortisol and cordifolone, Pakistan J. Sci.Industry Res. 14 (1970) 481–483
  28. S.N. Dixit, R.L. Khosa, Chemical investigations on Tinospora cordifolia (wild.) Miers, Indian. J. Appl. Chem. 34 (1971) 46–47.
  29. D.N.K. Sarma, R.L. Khosa, J.P.N. Chansauria, A.K. Ray, The effect of Tinospora cordifolia on brain neurotransmitters in the stressed rat, Fitoterapia 66 (1995) 421–422.
  30. Jang MH, Piao XL, Kim JM, Kwon SW, Park JH. Inhibition of cholinesterase and amyloid-b aggregation by resveratrol oligomers from Vitis amurensis. Phyther K. Panneer Selvam, U. Payyappallimana, K. Ravikumar et al. Journal of Ayurveda and Integrative Medicine 14 (2023) 100658 7 Res 2008;22(4):544e9. Available from: http://www3.interscience.wiley.com/ journal/117934759/abstract.
  31. National Clinical Management Protocol based on Ayurveda and Yoga for management of COVID-19. 2020. Available from: http://www.ayush.gov.in/ docs/ayush-Protocol-covid-19.pdf
  32. Baghel P. Plant of versatile properties: a review of Tinospora cordifolia (Guduchi). Int J Agric Innov Res 2017;5(5):2319-
  33. India IBP. Biodiversity portal. Available from: https://indiabiodiversity.org/; 2021.
  34. Spandana U, Ali SL, Nirmala T, Santhi M, Sipai Babu SD. A review on Tinospora cordifolia. Int J Curr Pharm Rev Res 2013;4(2):61e8.
  35. Joshi B. Pharmacognostical review of Tinospora cordifolia. Inven Impact Planta Act 2016;2017(May):1e10.
  36. Nagarkar B. Comparative hepatoprotective potential of Tinospora cordifolia, Tinospora sinensis, and neem-Guduchi. Br J Pharmaceut Res 2013;3(4): 906e16.
  37. National NMPB. Medicinal plants board. 2021. Available from: https://nmpb. nic. in/medicinal_list
  38. Sinha K, Mishra N, Singh J, Khanuja S. Tinospora cordifolia (Guduchi), a reservoir plant for therapeutic applications: a Review. Indian J Tradit Knowl 2004;3(3):257e70.
  39. Parveen A, Adams JS, Raman V, Budel JM, Zhao J, Babu GNM, et al. Comparative morpho-anatomical and HPTLC profiling of Tinospora species and dietary Supplements. Planta Med 2020;86(7):470e81.
  40. Sereena K, Remashree AB, Vemballur P. Histological, Histochemical and phytochemical studies of the raw drug Amrita from different raw. Drug Markets of Kerala 2014;1(5):182e91.
  41. Patil VS, Malpathak NP. Micromorphoanatomical approach for comparative analysis of Tinospora cordifolia (Willd.) Miers and its adulterant plant using sem and cryostat. Pharm J 2017;9(1):39e45.
  42. Santhosh Kumar JU, Krishna V, Seethapathy GS, Ganesan R, Ravikanth G, Shaanker RU. Assessment of adulteration in raw herbal trade of important medicinal plants of India using DNA barcoding. 3 Biotech 2018;8(3):135. https://doi.org/10.1007/s13205-018-1169-3. Epub 2018 Feb 15. PMID: 29479511; PMCID: PMC5814391

Photo
Kapil Dnyaneshwar Sirsath
Corresponding author

Department of Pharmacy, LBYP College Of D Pharmacy Pathri, India

Photo
Dr. D. K Vir
Co-author

Department of Pharmacy, LBYP College Of D Pharmacy Pathri, India

Photo
Dr. Gajanan Sanap
Co-author

Department of Pharmacy, LBYP College Of D Pharmacy Pathri, India

Kapil Sirsath*, Dr. D. K Vir, Dr. Gajanan Sanap, Potential Role Of Tinospora Cordifolia In Pharmaceuticals, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 11, 272-281. https://doi.org/10.5281/zenodo.10124466

More related articles
Formulation And Evaluation Of Polyherbal Antitus...
Kiran Kumari, Akhil Thakur, Ajeet Kumar, Nikhil Kumar, ...
Analytical Method Development And Validation For S...
Kartik A. Bhatkar, V. M. Waghulkar, M. P. Jadhao, M. D. Game, S. ...
Antimicrobial Activity Of Morus Alba Leaf Extract ...
Indranil Chatterjee, Bishan Sarkar, Pritam Ghosh, Suchetan Sarkar...
Formulation And Evaluation of Nanoparticles: A Review...
Muni Raja Lakshmi K, Lavanya E, Naseema Shaik, Vankata Rao Gadde, ...
Design And Characterization Of Polyherbal Single Use Soap For It’s Antibacteri...
Ankit P. Gondane, Samir R. Pakhidde, Sanket R. Ganvir , Tushar C. Bisen, Devesh R. Chourasia, ...
Related Articles
Molecular Docking: A Powerful Tool In Modern Drug Discovery And Its Approaches...
Shubhangi H. Bhowate, Dr. Dinesh R. Chaple, Dr. Alpana J. asnani, Pranita I. Rathod, Aishwarya V. Li...
Review Article On The Topiramate Transdermal Patches In The Pharmacy ...
Vaibhav Kore, Anita Rahile, Achal Lilhare, Hrushikesh Sultane, Bhumesh Lilhare, ...
Pharmacognostic Studies, Preliminary Phytochemical screening of vitex negundo l....
Dinesh Kumar Thakur, Dev Prakash Dahiya , Chinu Kumari , Akanksha Sharma , Bhopesh Kumar , Munish Ch...
Formulation And Evaluation Of Polyherbal Antitussive ...
Kiran Kumari, Akhil Thakur, Ajeet Kumar, Nikhil Kumar, ...
More related articles
Formulation And Evaluation Of Polyherbal Antitussive ...
Kiran Kumari, Akhil Thakur, Ajeet Kumar, Nikhil Kumar, ...
Analytical Method Development And Validation For Simultaneous Estimation Of Anti...
Kartik A. Bhatkar, V. M. Waghulkar, M. P. Jadhao, M. D. Game, S. G. Jawarkar, ...
Antimicrobial Activity Of Morus Alba Leaf Extract Against Potent Oral Pathogens ...
Indranil Chatterjee, Bishan Sarkar, Pritam Ghosh, Suchetan Sarkar, ...
Formulation And Evaluation Of Polyherbal Antitussive ...
Kiran Kumari, Akhil Thakur, Ajeet Kumar, Nikhil Kumar, ...
Analytical Method Development And Validation For Simultaneous Estimation Of Anti...
Kartik A. Bhatkar, V. M. Waghulkar, M. P. Jadhao, M. D. Game, S. G. Jawarkar, ...
Antimicrobial Activity Of Morus Alba Leaf Extract Against Potent Oral Pathogens ...
Indranil Chatterjee, Bishan Sarkar, Pritam Ghosh, Suchetan Sarkar, ...