View Article

  • Phytochemicals and pharmacological Activities in Abutilon indicum L.plant A Review
  • PG and Research Department of Biotechnology, Dr. N. G. P. Arts and Science College, Kalapatti road, Coimbatore, Tamil Nadu, India

Abstract

The Abutilon indicum L. is a branch of the Malvaceae Family of plants. It possesses numerous significant medicinal qualities. It is grown throughout tropical and subtropical regions of the world, including the hottest areas of India. In siddha treatment, plant parts like as root, bark, flowers, leaves, and seeds are used to cure leprosy, piles, ulcers, diabetes, and jaundice. In this plant contains flavonoids, tannin, asparagine’s, hexoses, alkaloid, mucilage, n-alkane mixtures and more phytochemicals. The plant Abutilon indicumhad anti-diabetic, antibacterial, antioxidant, antiulcer, analgesic and wound healing activities of pharmacological properties occurs. The synthesis of AgNPs, CuO, NiO, Gold, and ZnO nanoparticles from extraction of Abutilon indicum L. and their properties checked in plants, animals and humans. Green synthesis of nanoparticles and their characterization was performed using UV-Vis-Spectrophotometry (Quantitative check), TEM (size and morphology), GC-MS(phytochemical analysis), FTIR (stability and functions), and XRD (crystal structure of sample). Different applications of NPs can be used various industries for production of food, cosmetics, biofertilizers, pesticides, dyes and pharmaceutical product production

Keywords

Abutilon indicum, medicinal uses, phytochemical analysis, pharmacological activities, NPs production.

Reference

  1. Geetha, A.A.R,  Geetha, R., Venkatesan, P., Geetha, K (2008). “Isolation and identification of mosquito larvicidal compound from Abutilon indicum (Linn.) Sweet”. Parasitology research 102, 981-988.
  2. Â N Sri Kumaran (2017). “Biosynthesis of silver nanoparticles using Abutilon indicum (Link): An investigation of anti-inflammatory and antioxidant potential against carrageen induced paw edema in rats”. Asian Journal of Pharmaceutics (AJP) 11 (02).
  3. Singhai, A.K. (2013). “Abutilon indicum Linn: A phytopharmacological review”. Int J Pharm Chem 3, 2231-81.
  4. Acevedo- Rodriguez, P. & Strong, M.T. (2012). “Catalogue of seed plants of the West Indies”. Smithsonian Contributions to Botany 98: 1-1192.
  5. Sureshpandian, C., Gandhi P. (2021). Department of Botany. “Impact of culture media and growth hormones on callus induction in Abutilon indicum L. through leaf explants”. JRAR, 8 (2), E-ISSN 2348-1269, P-ISSN 2349-5138.
  6. D. P. Pandey, M. A. Rather, D. P. Nautiyal and R. K. Bachheti (2011). “Phytochemical analysis of Abutilon indicum”. International journal of ChemTech Research. CODEN (USA), 3 (2): 642-645.
  7. Dashputre NL, Naikwade NS (2011). “Evaluation of anti-ulcer activity of methanolic extract of Abutilon indicum leaves in experimental rats”. Int J Pharm Sci Drug Res3, 97–100.
  8. Dashputre NL, Naikwade NS, (2010). “Immunomodulatory Activity of Abutilon indicum Linn on albino Mice”. International journal of pharma science and research, 1(3), 178-184.
  9. Faheem Ijaz, Sammia Shahid, Shakeel Ahmad Khan, Waqar Ahmad, Sabah Zaman, (2017). “Green synthesis of copper oxide nanoparticles using Abutilon indicum leaf extract: Antimicrobial, antioxidant and photocatalytic dye degradation activities”. Tropical Journal of Pharmaceutical Research 16 (4): 743-753.
  10. Fosberg, F.R., Sachet, M-H., Oliver, R. (1979). “A geographical checklist of the Micronesian Dicotyledonae”. Micronesica; Journal of the college of Guam 15, 41- 295.
  11. Giri. R. K. Kaungo, S. K. Patro, V. J. Das, S. Sahoo, D. E. (2009). “Lipid lowering activity Abutilon indicum leaf extract in rats”. Journal of pharmacy research. 1725- 1727.
  12. Prashanth, G.K., Prashanth, P.A., Nagabhushana, B M et al. (2018). “Comparison of anticancer activity of biocompatible ZnO nanoparticles prepared by solution combustion synthesis using aqueous leaf extracts of Abutilon indicum”, Melia azedarach and indigofera tinctoria as biofuels Artificial cells, nanomedicine, and biotechnology 46 (5): 968-979.
  13. Goyal, N., Singh, S., Sharma and Surendra K (2009). “Analgesic effects of various extracts of the root of Abutilon indicum”. Journal of Pharmacy and Bioallied Sciences 1(1): 43-46.
  14. Chandirika, J.U., Annadurai. G. (2018). “Biosynthesis and characterization of silver nanoparticles using leaf extract Abutilon indicum”.J. Biotechnol. Biochem 13, 7-11.
  15. Chandirika, J.U. and Annadurai, G. (2018). Environmental Nanotechnology Divisions, Sri Paramakalyani Centre for Environmental science. “Biosynthesis and Characterization of silver nanoparticles using leaf extract Abutilon indicum”. Global journal of biotechnology & biochemistry 13(1): 07-11.
  16. Johri RK, Pahwa GS, Sharma SC, Zutshi U(1991), “Determination estrogenic/ antiestrogenic potential of antifertility substances using rat uterine peroxidase assay”, contraception, 44(5): 549-557.
  17.  Rout, J.R., Mishra, M., Das, R., Sahoo, S.L., (2004). “ In vitro Micropropagation of Abutilon indicum L. through leaf explants”. Plant tissue cult. & Biotech. 19(2): 177-184.
  18.  Eswari, K.M., Asaithambi, S., Karuppaiah, M., Sakthivel, P. et al. (2022). “Green synthesis of ZnO nanoparticles using Abutilon Indicum and Tectona Grandis leaf extracts for evaluation of anti-diabetic, anti-inflammatory and in-vitro cytotoxicity Activity”. Ceramics International 48 (22): 33624-33634.
  19. Ramar, K. and Ayyadurai, K (2015). “The present investigation deals with in vitro callus induction and plant regeneration of Abutilon indicum (L)”.Journal of pharmacognosy and phytochemistry 3 (6): 248-251,
  20. Kailasam, K.V. (2015). “Abutilon indicum (Linn.) Malvaceae – Medicinal potential review”. Pharmacognosy Journal 7 (6):45-49.
  21. Krisanapun C, Lee SH, Peungvicha P, Temsiririrkkul R, Baek SJ (2011). “Antidiabetic Activities of Abutilon indicum (L.) Sweet are mediated by enhancement of adipocyte differentiation and activation of the GLUT1 promoter”. Evid Based Complement Alternat Med. 2011 167684.
  22. Lakshmayya Narasimha, R. et al. (2002). “Phytochemical and pharmacological evaluation of leaves of Abutilon indicum”.  Indian journal of traditional knowledge. 2(1): 79-83.
  23. Lokesh R, Manasvi V, Praveena LB (2016). “Antibacterial and Antioxidant activity of saponins from Abutilon indicum leaves”. Asian journal of pharmaceutical and clinical research. 9(3): 23-29.
  24. M. Prathap, A. Alagesan, B.D. Ranjitha Kumar (2014). “Anti- bacterial activities of silver nanoparticles synthesized from plant leaf extract of Abutilon indicum (L) sweet”. Journal of nanostructure in chemistry volume 4, Article number: 106.
  25. Matlawska I, Sikorska M (2002). “Flavonoid compounds in the flowers of Abutilon indicum”.Acta Pol Pharm, 59(3): 227-9.
  26. Md. Reyad-ul-ferdous, Mehedi Rahman, Kawsar Mahamud, Sharmi Sultana Ayshi, Md. Didaruzzaman Sohel (2015). “Pharmacologicals and Phytochemicals Potential of Abutilon indicum: A Comprehensive Review”. American Journal of BioScience. Special Issue: Pharmacological and Phytochemicals Investigation. 3(2): 5-11.
  27. Mendhekar, S Y, Bangar, MS. et al (2018). “Pharmacognostic, Phytochemical, Physicochemical and Detail Microscopical Evaluation of Leaves Abutilon Indicum (L.) Sweet Ssp. Indicum Family (Malvaceae)”.International Journal of Pharmaceutical, Chemical & Biological Sciences, 8(1): 110-117.
  28. Chowdhury, MA, Hossain, N., Kchaou, M., Nandee, R., Shuvho, MB et al. (2021). “Scope of eco-friendly nanoparticles for anti-microbial activity”. Current Research in Green and Sustainable Chemistry 4, 100198.
  29. Deshpande, V., Jadhav, VM., Kadam, VJ, Rajesham et al. (2009). “Anti-arthritic activity of Abutilon indicum (Linn.) Sweet”, Journal of Pharmacy Research, 2(4): 644-645, ISSN: 0974-6943.
  30. Mohite, MS, Shelar, PA, Raje, VN, Babar, SJ, Sapkal, RK (2012). “Review on Pharmacological Properties of Abutilon indicum”. Asian journal of Pharmaceutical research 2 (4): 156- 160.
  31. Evansiddaya, RK, Kalyani., B, Veerangouda, A (2011).  “Hepatoprotective and antioxidant role of flower extract Abutilon indicum”. International journal of pharmaceutical and biological archives, 2(1):541-545.
  32. Rajeshwari S, Sevarkodiyone SP (2018). “Medicinal properties of Abutilon indicum”. Open J Plant Sci 3(1): 022-025.
  33. Mata, R., Reddy J., Sadras, NSR (2015). “Biogenic silver nanoparticles from Abutilon indicum: Their antioxidant, antibacterial and cytotoxic effects in vitro”. Colloids and surfaces B: Biointerfaces, 128, 276-286.
  34. Mata, R., Nakkala, J.R., Chandra, VK, Sadras, RK (2018). “In vivo bio-distribution, clearance and toxicity assessment of biogenic silver and gold nanoparticles synthesized from Abutilon indicum in Wistar rats”. Journal of Trace Elements in Medicine and Biology 48, 157-165.
  35. Roshan S, Ali S, Khan A, Tazneem B, Purohit MG (2008), “Wound healing activity of Abutilon indicum”. Pharmacognosy magazine, 4(15), 85-88.
  36. Sagar Panhwar, Jamil A Buledi, Dadu Mal, Amber R Solangi, Aamna Balouch, Ali Hyder (2021). “Importance and analytical perspective of green synthetic strategies of copper, zinc, and titanium oxide nanoparticles and their applications in pathogens and environmental remediation”. Current Analytical Chemistry 17 (8): 1169-1181.
  37. Saini, A. Gahlawat, D. K. Chauhan, C. Guila et al (2015). “Ethnomedicinal uses and phytochemistry of Abutilon indicum Linn sweet: an overview”. Journal of pharmacognosy and phytochemistry, 3: 66-72.
  38. Umavathi, S., Subash, M., Gopinath, K., Alarifi, S., Nicoletti, M., Govindarajan, M. (2021). “Facile synthesis and characterization of ZnO nanoparticles using Abutilon indicum leaf extract: An eco-friendly nano-drug on human microbial pathogens”. Journal of Drug Delivery Science and Technology 66, 102917.
  39. Sathiyavimal, S., Durán-Lara, EF., Vasantharaj, S., Saravanan, M. et al. (2022). “Green synthesis of copper oxide nanoparticles using Abutilon indicum leaves extract and their evaluation of antibacterial, anticancer in human A549 lung and MDA-MB-231 breast cancer cells”. Food and Chemical Toxicology 168, 113330.
  40. Sen Seth & Jogeswar Panigrahi. (2018). “In vitro organogenesis of Abutilon indicum (L) sweet from leaf derived callus and assessment of genetic fidelity using ISSR markers”. The journal of horticultural science and biotechnology, volume 94, 2019- issue 1, published online: 70- 79.
  41. Khan, SA. Noreen, F., Kanwal, S.,  Iqbal, A., Hussain, G. (2018). “Green synthesis of ZnO and Cu-doped ZnO nanoparticles from leaf extracts of Abutilon indicum, Clerodendrum infortunatum, Clerodendrum inerme and investigation of their biological and photocatalytic activity”. Materials Science and Engineering: C 82, 46-59.
  42. Khan, SA.,  Shahid, S., Ayaz, A., Alkahtani, J., Elshikh, MS, Riaz, T. (2021). “Phytomolecules-Coated NiO Nanoparticles Synthesis Using Abutilon indicum Leaf Extract: Antioxidant, Antibacterial, and Anticancer Activities”. International Journal of Nanomedicine, 1757-1773.
  43. Khan, SA., Sahid,S., Shahid, B., Fatima, U.,  Abbas, SA (2020). “Green Synthesis of MnO Nanoparticles Using Abutilon indicum Leaf Extract for Biological, Photocatalytic, and Adsorption Activities”. Biomolecules 10 (5): 785.
  44. Ahmed, S., Ahmad, M., Swami, B.L., Ikram, S. (2016). “A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise”. Journal of advanced research 7 (1): 17-28.
  45. Singh B, Saxena AK, Chandan BK, Suri OP, Suri KA, Sathi NK (1998). “Hepatoprotective activity of verbenalin on experimental liver damage in rodents”. Fitoterapia 60, 135.
  46. Singh R, Mendhulkar, VD (2015). “FTIR studies and spectrophotometric analysis of natural antioxidants, polyphenols and flavonoids in Abutilon indicum (Linn) sweet leaf extract”. Journal of Chemical and Pharmaceutical Research 7 (6): 205-211.
  47. Mittal, S and Roy, A (2021). “Fungus and plant-mediated synthesis of metallic nanoparticles and their application in degradation of dyes”. Photocatalytic degradation of dyes, 287-308.
  48. Krishnan, Sr., Pandian, S., Ramesh, M  et al (May 2019). “Augmenting a competent in vitro organogenesis etiquette from leaf base of country mallow, Abutilon indicum L. sweet: An ethno- botanically valuable medicinal plant”. Biocatalysis and agricultural biotechnology, 19, 101125.
  49. Vaidya, A. B. (1997). “The status and scope of Indian medicinal plants acting on central nervous system”, Indian journal pharmacology, 29: 340-343.
  50. Y.N. Seetharam, Chalageri, G. et al (2002). “Hypoglycemic activity of Abutilon indicum leaf extracts in rats”. Department of pharmacology, Elsevier, fitoterapia 73, 156-159.

Photo
Palaniswamy R*
Corresponding author

PG and Research Department of Biotechnology, Dr. N.G.P. Arts and Science College, Kalapatti road, Coimbatore, Tamil Nadu, India

Photo
Divyabharathi R
Co-author

PG and Research Department of Biotechnology, Dr. N.G.P. Arts and Science College, Kalapatti road, Coimbatore, Tamil Nadu, India

: Divyabharathi R., Palaniswamy R.*, Phytochemicals and pharmacological Activities in Abutilon indicum (L).plant– A Review, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 192-201. https://doi.org/10.5281/zenodo.10352714

More related articles
A Review On Beyond Conventional: Itraconazole Nios...
Rehan khan , Tushar Rukari, Vijay Jagtap, ...
Revitalizing Pharmacy Education: Leveraging Freshers' Insights To Level Up Pedag...
S. G. Santhoshkumar, M. Jeyarahavi, S. Jerlin Epsiba, M. Manoj Gupta, Niranjani, T. Vishnu, ...
Decoding Benzophenone Derivatives: A Deep Dive Into Biofluid Analysis Using LC-M...
SANOOJA P.K, PRASANTH S.S, AJAY A, MOHAMED FAROOQ. P, SIBINA M.K, JISHA .U, K.T. AKSHARA, RIYA RAJAN...
Review On Dengue Virus Prevention And Treatment...
Lamkhade Kanchan S, Lamkhade Sandhya V, Fatakkar Renuka B, Gahire Pratiksha D, Umbarde Rupali P, ...
Related Articles
Advances in bioavailability enhancement technique for poorly aqueous soluble dru...
Adithi P, Chaithra K, Chandana N, Deepthi R, Dhruva R Nadig, ...
Computational analysis of liver inflammation related genes in Human (Homo sapien...
Rizwan Shaukat, Hafsa Arshad, Iftikhar Ahsan Khan, Afifah Jabeen, ...
Formulation and Evaluation of Anti-acne Herbal Gel...
Arun Kumar K. V., Jusaira Abdul Jabbar, Sayooj V., Aromal M., Anakha S., Mufeeda, ...