Department of Chemistry , The Islamia university of Bahawalpur, Pakistan, The faculty of chemical and biological sciences
The multifaceted strategy used in contemporary exploration on the development of new medicines from medicinal shops combines botanical, phytochemical, biochemical combinatorial chemistry, and bioassay- guided separation ways. Natural coffers continue to offer an volition to pharmacological leads in the fight against multitudinous deadly conditions as diabetes, cardiovascular complaint, cancer, etc. There’s a huge global demand for medicinals that are both safe and effective moment. Scientists are now turning again to natural coffers as a possible source of drugs for the treatment and operation of similar habitual and deadly conditions as a result of this. Still, there are also significant obstacles and constraints in this area, similar as the scale- up and commercialization of active substances, which only allow one out of every a thousand lead motes to be turned into a drug. Medicine development requires a rigorous, scientific approach as a abecedarian component from natural resource. This mini review provides an overview of the styles involved in natural product exploration starting from crude factory excerpt to bioactive pharmacological lead. Also, it also discusses the limitations of working concerning the bioactivity of medicinal shops.
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Maryam javaid, Kainat Javeed, Natural Product Research for Drug Development: Methods, Limitations, and Potential Applications, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 11, 356-364. https://doi.org/10.5281/zenodo.10149044
10.5281/zenodo.10149044
