1B. Pharma, Pharmacy College Azamgarh
2B. Pharma, Pharmacy College Azamgarh
3Assistant Professor (Pharmaceutics), Pharmacy College Azamgarh
4Associate Professor (Pharmaceutical Chemistry), Pharmacy College Azamgarh
5Associate Professor (Pharmaceutics), Pharmacy College Azamgarh
This review article focuses on the Microbes Drug Delivery System. The Microbial drug delivery system is an emerging form of drug administration characterized by the use of commensal microbes that have been genetically modified to produce medications for chronic diseases in humans. The drug delivery system now a days, very popular for its therapeutic effects and prolonged action. The most prominent route of administration used for it, is topical route of administration due to which it avoids first pass metabolism. There are various forms available for drug delivery system, which contributes to enhance the patient compliance. Drug delivery system is a method of administration for pharmaceutical medication to achieve a therapeutic effect in humans or animals. There are various routes available for drug delivery such as the oral, topical, parentral, inhalation, transdermal, transmucosal and implantable systems. The drug delivery system further divided into two types, Conventional drug delivery system is the classical method for the delivery of drug into the body and Novel drug delivery system is a new approach that utilizes new technologies, innovative ideas and methodologies to deliver the active molecules in safe yet effective concentration to produce desired pharmacological action. The human microbiome is known to play an essential role in influencing host health. Extracellular vehicles (EVs) have also been reported to act on a variety of signaling pathways, distally transport cellular components such as proteins, lipids, and nucleic acid, and have immunomodulatory effects. In this review article we have discussed about the Microbes based drug delivery system by taking the examples of Human microbiome and extracellular vesicles.
Archana chauhan, Pradeep Yadav, Kakli Rai, Jitendra Jena, Jitendra Kumar Rai, Microbes Drug Delivery System- A Comprehensive Review, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 1, 23-32. https://doi.org/10.5281/zenodo.10455555