1Professor and Head, Department Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka 574143
2PharmD Intern, Department of Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka 574143
One of the leading causes of maternal morbidity and mortality during pregnancy is pregnancy-induced hypertension. Hypertension that persists complicates between 1% and 5% of pregnancies. A combination of ?- and ?-adrenoceptor antagonist, labetalol is currently used to treat hypertension. It functions as a competitive antagonist of postsynaptic ?-adrenoceptors and a nonselective competitive antagonist at ?-adrenoceptors. Comparing it to other ? blockers, it can preserve uteroplacental circulation more effectively. Additionally, a comparison was done between labetalol and other medications used for comparable purposes.
A. R. Shabaraya, Lathika A. Nayak, Labetalol For The Treatment Of Pregnancy Induced Hypertension: A Brief Review, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 78-87. https://doi.org/10.5281/zenodo.10259558