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  • Labetalol For The Treatment Of Pregnancy Induced Hypertension: A Brief Review
  • 1Professor and Head, Department Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka 574143
    2PharmD Intern, Department of Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka 574143

Abstract

One of the leading causes of maternal morbidity and mortality during pregnancy is pregnancy-induced hypertension. Hypertension that persists complicates between 1% and 5% of pregnancies. A combination of ?- and ?-adrenoceptor antagonist, labetalol is currently used to treat hypertension. It functions as a competitive antagonist of postsynaptic ?-adrenoceptors and a nonselective competitive antagonist at ?-adrenoceptors. Comparing it to other ? blockers, it can preserve uteroplacental circulation more effectively. Additionally, a comparison was done between labetalol and other medications used for comparable purposes.

Keywords

Pregnancy induced hypertension, postsynaptic, labetalol, antagonist, combination

Reference

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Photo
Lathika A Nayak
Corresponding author

Pharm D Intern; Department of pharmacy practice, Srinivas college of pharmacy

Photo
A. R. Shabaraya
Co-author

Professor and Head, Department Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka 574143

A. R. Shabaraya, Lathika A. Nayak, Labetalol For The Treatment Of Pregnancy Induced Hypertension: A Brief Review, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 78-87. https://doi.org/10.5281/zenodo.10259558

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