Matoshri Institute of Pharmacy Dhanore, Yeola, (Nashik, Maharashtra)
The demand for safe and effective hair removal products has led to a surge in the development of herbal formulations. This study aimed to formulate and evaluate a herbal hair removal cream using natural ingredients known for their depilatory properties. The formulation was developed utilizing a combination of plant extracts with proven hair inhibitory effects, emulsifiers, stabilizers, and skin-nourishing agents. The formulated herbal hair removal cream underwent a series of evaluations to assess its physicochemical properties, including pH, viscosity, spread ability, and stability. Additionally, the efficacy of hair removal was evaluated through in vitro and in vivo studies. The in vitro study involved testing the cream on artificial hair samples, while the in vivo study was conducted on human volunteers. Results from the physicochemical evaluations demonstrated that the formulated cream possessed suitable characteristics for topical application, such as a neutral pH, optimal viscosity, and good spread ability. Furthermore, the cream exhibited excellent stability under various storage conditions. The efficacy evaluations revealed promising results, with the herbal hair removal cream demonstrating significant hair reduction in both in vitro and in vivo studies. Moreover, the cream exhibited no adverse effects on the skin, indicating its safety for use. In conclusion, the formulated herbal hair removal cream showed potential as a safe and effective alternative to conventional depilatory products. Further research is warranted to optimize the formulation and explore its long-term efficacy and safety profiles for commercialization.
The formulation and evaluation of an herbal hair removal cream utilizing Prosopis cineraria extract present an innovative approach towards developing a natural and sustainable solution for hair removal. The inclusion of Prosopis cineraria in the formulation is based on its historical usage and emerging scientific evidence supporting its depilatory properties. Its bioactive constituents, such as saponins and flavonoids, are believed to interfere with hair growth cycles, leading to reduced hair density and thickness. This study aims to explore the feasibility of incorporating Prosopis cineraria extract into a topical cream formulation for hair removal. By leveraging the natural depilatory potential of this botanical ingredient, the formulated cream seeks to offer an alternative to chemical-based depilatories, addressing concerns related to skin sensitivity and adverse reactions. Through systematic formulation development and rigorous evaluation, this research endeavors to assess the physicochemical properties, stability, and efficacy of the herbal hair removal cream. Furthermore, considerations regarding safety and compatibility with skin types will be paramount in ensuring the acceptance and adoption of the product. The utilization of Prosopis cineraria in herbal hair removal formulations not only aligns with the growing consumer preference for natural products but also holds promise for sustainable sourcing and cultivation practices. By harnessing the traditional knowledge of indigenous botanicals and integrating it with modern scientific methodologies, this study aims to contribute to the development of innovative and eco-friendly solutions in the field of cosmetic science. The pursuit of smooth, hair-free skin has been a timeless endeavor, prompting continuous innovation in the field of hair removal products. In recent years, there has been a discernible shift towards natural and herbal alternatives, driven by growing concerns regarding the safety and long-term effects of conventional depilatory methods. This paradigm shift underscores the importance of formulating herbal hair removal creams that offer efficacy while minimizing the risk of adverse reactions. Herbal ingredients have been revered for their therapeutic properties in various cultural traditions f131or centuries. Harnessing the potential of these botanicals for hair removal purposes not only aligns with the demand for safer alternatives but also taps into a wealth of traditional knowledge. The formulation and evaluation of herbal hair removal creams represent a convergence of ancient wisdom and modern science, offering a compelling solution to contemporary needs. This study focuses on the formulation and evaluation of an herbal hair removal cream, leveraging the vast repository of botanical extracts known for their depilatory effects. By carefully selecting and combining botanical ingredients with proven hair inhibitory properties, this research aims to develop a formulation that not only removes unwanted hair effectively but also nourishes and soothes the skin.
MATERIALS AND METHOD:
Prosopis cineraria
Prosopis cineraria is a multipurpose species that influences soil improvement and sand dune stabilization in addition to offering food, fuel, shade, lumber, and fodder. In Pakistan and India, it is frequently employed in dryland agroforestry. Local names for the tree include Ghaf (Arabic), jand (Pakistan), and jandi or khejri (India). P. spicigera is its synonym.
BOTANY:
Within the genus of leguminous trees and shrubs, Prosopis cineraria (L.) Deuce is one of 44 species (family Leguminosae, subfamily Mimosoideae). It is a tiny, 5–10 m tall, prickly tree with sporadic branches. It has an open crown, thick, rough, Gray bark with deep cracks, and is either evergreen or almost. The alternating, bipinnately complex leaves have one to three pairs of pinnae. There are 7–14 pairs of 4–15 mm length and 2-4 mm wide leaflets on each pinna. The thorns are spaced sporadically over the length of the stem and are straight with a conical base. Prosopis is a moderate size thorny tree, evergreen or nearly so, with light foliage and straggling rather slender branches armed with conical prickles. It does not exceed a height of 40ft. and a girth of 4 ft., the maximum attained being 50ft. and 6ft. respectively. Bark rough, exfoliating in thin flakes. Stem are erect at first, soon branching and becoming straggling, zigzag at the nodes, glabrous, green or reddish, covered with prickles which are at first minute, later 0.1-inch-long, internodes 2-.3-inch long. Roots are Primary root, long, thin, tapering, wiry, yellow turning brown: Lateral root few, short, fibrous, distributed down main root: nodules present. Leaves are alternate. Stipules 0.2 by 0.1 inch falcate, mucronate, green. First leaf pinnate, rachis 0.5-inch-long with occasional rudimentary or minute prickles, leaflet usually in 5 pairs opposite, with very short petiolules, 0.2 to by 0.1 inch obliquely oblong, mucronate, entire. Subsequent leaves bipinnate with one pair of opposite pinnae; rachis 0.1 to 0.2-inch-long, pinnae 0.3 to 0.6 inch with 4-6 later 7-8 pair of leaflets similar to those of first leaf. Flowers are small, cream-yellow clustered in acute spikes 5-23 cm long with a 1-2.5 mm long peduncle. Pods are pale yellow, 8-25 cm long x 4-8 mm wide, cylindrical and hanging, containing 10-25 seeds ovoid in shape and dark brown in colour, packed in a brown pulp. Seeds- are 0.2 to 0.3 inch, compressed, ovate, oblong or rhomboidal, brown, smooth, hard, with a moderately hard testa. The seed retains its vitality for at least a year.
Turmeric powder:
Turmeric is often included in hair removal creams for its natural properties that can inhibit hair growth and soothe the skin. Here's how it contributes to hair removal cream:
However, it's important to note that the effectiveness of turmeric in hair removal creams may vary from person to person, and results may not be immediate or permanent. Additionally, individuals with sensitive skin or allergies to turmeric should exercise caution when using products containing this ingredient.
Ginger powder:
Ginger is sometimes included in hair removal creams due to its various beneficial properties for the skin and its potential to inhibit hair growth. Here's how ginger contributes to hair removal cream:
While ginger may offer benefits when included in hair removal creams, it's important to note that individual results may vary. Some people may experience more significant hair growth inhibition or skin benefits than others. Additionally, individuals with sensitive skin or allergies to ginger should use caution when using products containing this ingredient.
Tusi powder:
Tulsi, also known as holy basil, is sometimes included in hair removal creams for its potential to inhibit hair growth and soothe the skin. Here's how Tulsi contributes to hair removal cream:
Overall, while Tulsi may offer some benefits when included in hair removal creams, it's essential to note that individual results may vary. Additionally, individuals with sensitive skin or allergies to Tulsi should use caution when using products containing this ingredient. Consulting with a dermatologist before using such products is advisable, especially if you have any skin concerns or conditions.
Neem powder:
Neem, known for its various medicinal properties, is sometimes included in hair removal creams due to its potential to inhibit hair growth and its benefits for skin health. Here's how neem contributes to hair removal cream:
Neem is also moisturizing and nourishing for the skin. Including neem in hair removal creams can help hydrate and replenish the skin's moisture barrier, leaving it soft, supple, and healthy-looking.
While neem may offer benefits when included in hair removal creams, it's important to note that individual results may vary. Additionally, individuals with sensitive skin or allergies to neem should use caution when using products containing this ingredient. Consulting with a dermatologist before using such products is advisable, especially if you have any skin concerns or conditions.
Table No.1: Ingredients and their Role
Methodology:
Formula for depilatory cream:
Table No. 2 Formula
PROCEDURE:
Heat liquid paraffin, and stearic acid in a borosilicate glass beaker at 75° c and maintain that heating temperature (oil phase). Take mortal pestle and mix well turmeric powder, ginger powder, after that add mixed Powder slowly in the oil phase and stir continuously. Then add measured amount of neem and Tulsi extract and stir vigorously until it forms a smooth cream. Then add an active ingredient prosopis cineraria and thioglycolic acid in cream and stir continuously up to it mix well in cream. Then add some orange oil as a fragrance. Stir it properly until proper cream was formed.
Evaluation Of Cream: -
RESULT AND DISCUSSION:
Table no. 3 result and discussion
CONCLUSION:
In this Formulation these ingredients are used that are neem powder, Tulsi powder, ginger powder, thioglycolic acid, bees wax, liquid paraffin, stearic acid, and the main drug is prosopis cineria. and perform the 4 batches that are F1, F2, F3, F4. F2 batch gives the satisfactory result. So, the F2 batch is main formulation of herbal hair removal cream.
REFERENCES:
Rajnandini P. Rathod, Gauri K. Khohad, Aniket A. Magar, Radhika Kotame, Herbal Hair Removal Cream From Prosopis Cineraria, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 6, 656-662. https://doi.org/10.5281/zenodo.11610929