Department of Pharmaceutics, Shraddha Institute of Pharmacy Washim-444505.
Aging skin is caused by a persistent process of degradation and harm to DNA and proteins in cells. Our study's primary goal i s to create a cream with polyherbs to prevent aging. In our preparation, we used herbal ingredients such as tulsi leaves, butterfly pea flowers, aloe vera gel, oil of turmeric. The presence of anthocyanins is indicated by the fact that butterflies contain cyanin, yanin, and anthocyanins, which are natural antioxidants that slow down the Tulsi leaves are used to treat skin aging and as an antibacterial. VestaVeuse moisturiturmeric, zer, and oilluminizing.sing. minimize acne and lighten dark circles. These are a few of the basic medications used in the cream's formulation. In assessing the quality of formulation [f1–f5] was carried out using various parameters, such as pH, viscosity,phase separationon and spreadability. The formulation of n.F3 is superior to all others formulation. The anti-aging cream’s physical characteristics remained unchanged. The formulation had no phase and good spreadability. separation and high uniformity. It is discovered that the cream’s viscosity is sufficient. The formulation of the polyherbal cosmetics is safe, stable at temperature, and can be applied to the skin without risk. Skin aging is brought on by a persistent degradation process brought on by damage to cellular DNA and protein Aging is classified into two distinct categories: “sequential skin aging” and “photo-aging.” Both types have distinct clinical and historical traits. Butterfly pea flowers are rich in antioxidant flavonoids and phenolic compounds that protect the skin from free radical-induced oxidative damage. Maximizing allocation was the aim of this study. mixture that contains butterfly pea flower extract (BPFE), triethanolamine (TEA), and as emulsifiers and to evaluate stearic acid's antioxidant potential. Eight different lotion formulas were developed using the Simplex Lattice Design method in Design Expert v13.0, with a focus on optimizing the proportion of TEA to stearic acid. Antioxidant activity is measured using DPPH (2,2-diphenyl-1- picrylhydrazyl) at a wavelength of 516 nm. Crucial elements such as pH, adhesion, and spreadability and measurements of viscosity were taken. Maceration was the method used to extract BPFE. Response efficiency. The refined mixture showed 6.26±0.38 cm of spreadability, adhesion of 3.2±0.2 s, 120 dPas of viscosity, and 7.19±0.005 pH. Both the optimized lotion and BPFE Strong antioxidant activity was demonstrated by the formulation, with IC50 values of 59.87±0.802 µg/ml and 84.52±1.418 µg/ml, in that order. The improved BPFE lotion formula shows encouraging possibility of becoming a coproduct. Growing awareness of artificial sunscreen’s harmful effects Agents are paying more attention to herbal alternatives. This study ?plans to develop and evaluate a herbal cream using Clitoria Þ?8Ternatea, or blue pea flower extract, is well known for its potent antioxidant and photoprotective properties. The extract was incorporated into a cream-based formulation using natural excipients. Phytochemical cream confirmed itsè³ presence of flavonoids, anthocyanins, and phenolic compounds. Compounds that enhance the plant’s ability to absorb ultraviolet light. Concerning anti-aging cream. Thus polyherbal cosmetics formulation is safe to use was stable at room temperature and can be safely used on the skin.
Taking care of their skin has always been important to humans. Youth is indicated by smooth, supple skin. However, collagen, a structural protein, is responsible for this flawless appearance. Collagen acts as a helpful cushion to keep the skin supple and forms an even layer underneath it. The thinning of the skin and the unevenness of the collagen padding beneath cause wrinkles to appear as we age. Premature aging can be brought on by excessive sun exposure, tobacco smoke, and dehydration. It is an inevitable part of aging naturally. The aging process can be somewhat slowed down with the right skin care and protective measures, degree. One of the primary causes of the collagen layer's degradation is oxidative stress. As a result of this need, skin care products have been continuously improved upon and created. preparations for cosmetic purposes. Preparations for skin care have existed since ancient times. It has long been practiced to preserve and beautify the skin by using slaves and unguents. They were
mostly made by breaking down gums, roots, flowers, and fragrant resins with fats and oils. Galen, a Greek physician, made the first significant modification in the second century. By adding water to his sales, A.D. That readiness was regarded as the cornerstone. contemporary cold and cleansing creams. However, throughout the ages, a constant Changes were made, but the fundamental idea stayed the same. It's now so It's crucial that significant resources and time are consistently allocated to research pertaining to with how different substances and treatments affect the skin and to create better skin care getting ready.The purpose of the current study was to prepare and assess an antiaging cream containing extracts of blue pea flower , Alovera gel , conflower powder, distilled water.
MATERIALS AND METHODS:
1) SELECTION OF RAW MATERIALS:
The materials for a formulation were selected on the basis study of different brief literature review and surfing of general and publication.
2) COLLECTION OF RAW MATERIALS:
Blue pea flower, Alovera, Cornflour powder, Moroccan Argan oil
3) EXCIPIENTS AND HERBAL INGREDIENTS WITH THEIR ROLE:
Table no.1 Role of Ingredients
|
Sr.No |
Ingredients |
Role |
|
1. |
Butterfly pea flower extract |
Antioxidants, Anti-inflammatory |
|
2. |
Aloe Vera gel |
Anti-ageing, anti-inflammatory, moisturizer, reduce acne and pimples. |
|
3. |
Cornflower powder |
calm skin irritation, reduce redness, and refresh tired or sensitive skin. |
|
4. |
Moraccan Argan Oil |
Natural emollient, moisturizer, and antioxidant |
|
5. |
Vitamin E Capsule |
Skin-conditioning, anti-aging, and protective agent |
|
6. |
Borax |
Emulsifying agent, stabilizer and gives thickness to the cream |
|
7. |
Beeswax |
Alkaline agent which react to emulsifying agents |
METHOD:
1. Extraction process:
Anthocyanin extraction From Butterfly pea Flowers:
Use fresh or dried butterfly pea flowers. If using fresh flowers, Rince them to improve dirt and impurities.
2. Maceration (Soaking)
Add the flowers to a glass or stainless-steel container. Pour distilled water over the flowers in 10 to 20 ml of water per gram of flowers. Stir the mixture gently to ensure even contact.
3. Extraction Time and Temperature:
Let the mixture sit at room temperature (25 -30°c) for 6-24 hours. For better efficiency, gentle stirring every few hours helps release the anthocyanins. Higher temperature (40-50°c) can improve extraction efficiency but may degrade anthocyanins over time.
4. Filtration:
After maceration, filter the extract using cheesecloth, a fine sieve, or filter paper to remove the solid residues
5. Concentration:
If more concentrated extract is needed, evaporate some of the water using a low-temperature method like vaccum evaporation or freeze -drying.
6. Storage:
Store the extract in an airtight dark-colored container to protect it from light degradation. Refrigerate(4°c) to extend shelf life
Fig no.1 Extraction of Butterfly Pea Flower
FLOWER EXTRACT
The growing demand for natural skincare has inspired the formulation of herbal night creams using plant-based ingredients that nourish and protect the skin. Among them, blue pea flower extract (Clitoria ternatea), or butterfly pea flower, is valued for its strong antioxidant, anti-inflammatory, and anti-aging properties. Rich in anthocyanins, flavonoids, and polyphenols, it helps repair skin, protect against environmental damage, and maintain a youthful glow.
When added to an anti-aging night cream, it enhances skin renewal, smoothness, and elasticity, reducing fine lines and improving texture. Free from parabens and artificial fragrances, the cream is safe for all skin types, including sensitive skin.
Quality testing includes stability, pH, spreadability, and while evaluations of viscosity, Greasiness and radiance confirm its effectiveness.
EXTRACTION OF ALOVERA GEL:
Mature, healthy and fresh aloe Vera leaves were collected and washed with distilled water. Then after proper drying of leaves in Hot air oven, the outer part of the leaf was dissected longitudinally using a sterile knife. Then the aloe Vera gel that is the colorless Parenchymatous tissue was removed using the sterile knife. Then it is filtered using muslin cloth to remove the fibers and impurities. Then the filtrate or the filter product which is a clear aloe Vera gel was used in the preparation.
FORMULATION OF CREAM:
Heat Oliv oil and beeswax in a borosilicate glass beaker at 75? and maintain that heating temperature. (Oil phase). In another Beaker, dissolve borax in distilled water and heat. This beaker to 75? to dissolve borax and and to get A clear solution. (Aqueous phase).
Then slowly add this aqueous Phase to heated oily phase. Then add a measured amount of aloe Vera gel, blue pea flower extract, cornflower powder, vitamin E Capsule and stir vigorously until it Forms a smooth cream. Then add few drops of morcaan argan oil as a fragrance. Put this cream on the container and label and store cool place.
Fig no.2 Butterfly Pea Flower Cream
EVALUATION OF CREAM
1. Appearance:
The appearance of the butterfly pea flower cream was examined after application, noting characteristic such as color, texture, odor, state.
2. Irritancy:
Mark the area (1 cm2) on the left-hand dorsal surface. Then the cream was applied to that area and the time was noted. Then it is checked for irritancy, erythema, and edema if any for an interval up to 24 h and reported
3. Wash ability:
A small amount of cream was applied on the hand and it is then washed with tap water
4. PH:
A small amount of the cream was applied to PH paper and compared against a standard pH color chart to estimate the pH level.
5. Viscosity:
Viscosity of cream was done by using Brooke field viscometer at a temperature of 25? using spindle No. 63 at 2.5RPM
6. Spread ability:
The spreadability was expressed in terms of time in seconds taken by two slides to slip off from the cream, placed in between the slides, under certain load. Lesser the time taken for separation of the two slides better the spreadability. Two sets of glass slides of standard dimension were taken. Then one slide of suitable dimension was taken and the cream formulation was placed on that slide. Then other slide was placed on the top of the formulation. Then a weight or certain load was placed on the upper slide so that the cream between the two slides was pressed uniformly to form a thin layer. Then the weight was removed and excess of formulation adhering to the slides was scrapped off. The upper slide was allowed to slip off freely by the force of weight tied to it. The time taken by the upper slide to slip off was noted.
Spread ability = m × l/t Where,
M= Standard weight which is tied to or placed over the upper slide (30g)
L= length of a glass slide (5cm) T= time taken in seconds.
7. Greasiness:
Here the cream was applied on the skin surface in the form of smear and checked if the smear was oily or grease-like
8. Dye test:
Dye test confirmed that all the cream formulations were o/w emulsions
9. Homogeneity:
All formulations produce uniform distribution of extracts in cream. This was confirmed by visual appearance and by touch
RESULT AND DISCUSSION
Evaluation results of all the 3 formulations are gives below.
Physical evaluation:
In this test color, odor, texture and state of the three formulations were examined.
Table 2: In this test colour odor, texture and state of the three formulations was checked
|
Sr.No |
Parameters evaluation |
F1 |
F2 |
F3 |
|
1 |
Color |
Green |
Light green |
Light green |
|
2 |
Odor |
Pleasant |
Pleasant |
Pleasant |
|
3 |
Texture |
Smooth |
Smooth |
Smooth |
|
4 |
State |
Semisolid |
Semisolid |
Semisolid |
CONCLUSION
In conclusion, butterfly pea flower cream is a skincare product that harnesses the benefits of butterfly pea flower extract, known for its antioxidant anti-aging, and soothing properties, when infused into a cream, it helps hydrates, rejuvenate, and protect the skin. The cream is often rich in natural ingredients like plant-based oils and aloe Vera gel, which contribute to its moisturizing andsmoothing effects. Regular use of butterfly pea flower cream may promote a healthier, more radiant complexation while offering potential anti-inflammatory benefits.
Furthermore, combining the extracts of Curcuma longa, Solanum lycopersicum, and Carica papaya in various proportions provides a multifunctional skincare effect, offering benefits such as skin whitening, anti-wrinkle, anti-aging, and sun-protective actions. While a single plant extract may have limited efficacy, the synergistic blending of multiple herbal extracts enhances their overall therapeutic and cosmetic potential. Thus, the formulated herbal cream demonstrates improved effectiveness and broader skincare benefits compared to individual plant extracts.
REFERENCES
Renuka Damodhar, Swati Kanoje, Dr. Swati Deshmukh, Formulation And Evaluation of Herbal Anti-Aging Cream from Blue Pea Flower, Int. J. of Pharm. Sci., 2026, Vol 4, Issue 4, 4827-4834, https://doi.org/10.5281/zenodo.19908871
10.5281/zenodo.19908871