View Article

Abstract

In the developed world, extreme prematurity is the leading cause of neonatal mortality and morbidity due to a combination of organ immaturity and iatrogenic injury. Due C-Section mother go through risk like blood loss, increase infection and major risk occurs due to anesthesia given during delivery. Now AWF or artificial uterus is technique used to develop foetus outside the body. This paper elaborate detail information about technique. Artificial wombs are expensive to develop and use, meaning they may only be accessible to those who can afford it. AWF may increase existing inequalities in society. This risk may overcome due to AWF technique. AWF include various component like nutrient, oxygen supplier, uterine wall, artificial placenta (Interface), Amniotic tank and Umbilical cord. The availability of computer-controlled artificial hearts, kidneys, and lungs, as well as the possibility of implanting human embryos in ex vivo uterus models or an artificial endometrium, presents new perspectives for creating an artificial uterus. Third, I demonstrate that clinical trials will be a necessary part of the clinical translation of AWF because of requirements laid out by regulators. I consider the justification for clinical trials and highlight some of the crucial ethical questions about the conditions under which they should proceed.

Keywords

Artificial Wombs, Medical Research, Neonatal Intensive Care, Partial Ectogenesis, Research Ethics, Ectolife

Reference

  1. Youtube. com, Ectolife Hashem-AL-Ghalli. 
  2. Youtube. com, Artificial womb, medical dialogues. 
  3. Jeff Wang and Mark V Sauer, In vitro fertilization (IVF): a review of 3 decades of clinical innovation and technological advancement, doi: 10. 2147/ tcrm. 2006. 2. 4. 355[Google Scholar]
  4. Edwards RG, Steptoe PC. Current status of in-vitro fertilization and implantation of human embryos. Lancet. 1983; 2:1265–9. [PubMed] [Google Scholar]
  5. Victoria S Jiang, Charles L Bormann, Artificial intelligence in the in vitro fertilization laboratory: a review of advancements over the last decade DOI: 10. 1016/j. fertnstert. 2023. 05. 149
  6. Technologyreview. com
  7. Kinga Skoracka, Alicja Ewa Ratajjczak, anna Maria Rychter, Agnieszka Dobrowolska, Female Fertility and the Nutritional Approach: The Most Essential Aspects, doi: 10. 1093/advances/nmab068
  8. www. ucsfhealth. org/treatments/extracorporeal-membrane-oxygenation, University of California San Francisco
  9. Berghella V, Baxter JK, Chauhan SP. Evidence-based surgery for cesarean delivery. Am J Obstet Gynecol. 2005 Nov; 193(5):1607-17. [PubMed]
  10. Artificial Wombs: The Future of Painless Childbirth. ” Nation, 4 Jan. 2022, nation. africa/kenya/healthy-nation/artificial-wombs-the-future-of-painless-childbirth-3671144
  11. Sathish Rajaa, Akkilangunta Sujiv, Sitanshu Sekar Kar, Risk factors for cesarean section in women of urban Puducherry, India: A matched case–control study
  12. Ahmmed, F. , Manik, M. M. R. , & Hossain, M. J. (2021). Caesarian section (CS) delivery in Bangladesh: A nationally representative cross-sectional study. PLoS One, 16(7), e0254777. https://doi. org/10. 1371/journal. pone. 0254777
  13. Arjun, G. (2008). Caesarean section: Evaluation, guidelines and recommendations. Indian Journal of Medical Ethics, 5(3), 117-120. https://doi. org/10. 20529/IJME. 2008. 043
  14. Abbey J Hardy-Fairbanks 1, Michele R Lauria, Todd Mackenzie, Martin McCarthy Jr, Intensity and unpleasantness of pain following vaginal and cesarean delivery: a prospective evaluation, DOI: 10. 1111/birt. 12039
  15. Sean Brian Yeoh, Sng Ban Leong, and Alex Sia Tiong Heng, Anaesthesia for lower-segment caesarean section: Changing perspectives, doi: 10. 4103/0019-5049. 71037
  16. Amy Norton, C-Section Raises Risk of Blood Clots After Childbirth[Article]
  17. Dr. A. SHAJI GEORGE. (2020). LAB-GROWN BREAST MILK: THE FORESEEABLE FUTURE OF INFANT NUTRITION. JASC: Journal of Applied Science and Computations, VII(VIII), 20–34
  18. E Hemminki, Impact of caesarean section on future pregnancy--a review of cohort studies, PMID: 8931052 DOI: 10. 1111/j. 1365-3016. 1996. tb00062. x
  19. A. S. Hovan George, Aakifa Shahul, & Dr. A. Shaji George. (2022). an Overview of Medical Care and the Paternalism Approach: An Evaluation of Current Ethical Theories and Principles of Bioethics in the Light of Physician-Patient Relationships. Partners Universal International Research Journal (PUIRJ) ISSN: 2583-5602, 01(04),https://doi. org/10. 5281/zenodo. 7419781 
  20. Timothy C. Bonebrake, Jon Christensen, Carol L. Boggs, Paul R. Ehrlich, Population decline assessment, historical baselines, and conservation
  21. A. Shaji George, Artificial Womb Technology: Analyzing the Impact of Lab-Grown Infants on Global Society, DOI:10. 5281/zenodo. 7673490
  22. Patricia S. Coffey and Siobhan C. Brown, Umbilical cord-care practices in low- and middle-income countries: a systematic review. doi: 10. 1186/s12884-017-1250-7
  23. Elizabeth Chloe Romanis, Artificial womb technology and clinical translation: Innovative treatment or medical research?, doi: 10. 1111/bioe. 12701
  24. Artificial Wombs: The Future of Painless Childbirth.” Nation, 4 Jan. 2022, nation. africa/kenya/healthy-nation/artificial-wombs-the-future-of-painless-childbirth-3671144.

Photo
S. S. Daud
Corresponding author

Nandkumar Shinde College of Pharmacy, Aghur, Vaijapur 423701 Dist. - Aurangabad, Maharashtra.

Photo
S. B. Dube
Co-author

Nandkumar Shinde College of Pharmacy, Aghur, Vaijapur 423701 Dist. - Aurangabad, Maharashtra.

Photo
S. R. Faruki
Co-author

Nandkumar Shinde College of Pharmacy, Aghur, Vaijapur 423701 Dist. - Aurangabad, Maharashtra.

Photo
T. A. Rajput
Co-author

Nandkumar Shinde College of Pharmacy, Aghur, Vaijapur 423701 Dist. - Aurangabad, Maharashtra.

S. S. Daud*, S. B. Dube, S. R. Faruki, T. A. Rajput, Ectolife –The Artificial Womb Facility, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 10, 200-204. https://doi.org/10.5281/zenodo.10031107

More related articles
A Review: Formulation of Herbal Lozenges for Incre...
Lina Durbale, Vaibhav Jain, Bhagyashri Meshram, ...
An Introduction To Pharmaceutical Excipients Use I...
Rajeshwari G. Khairnar, Aniket T. Chavan, Rupali R. Tasgaonkar, ...
Concept And Recent Advancement In Tablet Coating T...
Shrikant S. Dongare, Mr. Dnyaneshwar S. Vyavhare, Dr. Megha T. Sa...
A Review Article On Transforming Parkinson’s Disease Care :Innovative Treatmen...
Siddhant M. Sawant, Prashant J. Burange, Maithili P. Amale, Pankaj Chaudhary , ...
New Developments In The Photodynamic Therapy For Hypoxia Tumor By Using Oxphos-T...
Mayuri N. Jagtap, Avinash B. Darekar, Vedant Uday Dhoke, ...
A Review on: Pharmacogenomics with AI (Clinical Sematic Network )...
Amol V. Supekar, Tagare Chetan B., Girhe Akshay R., Tanpure Siddharth S., Zirpe Pandhori , ...
Related Articles
Cutting edge Techniques for Impurity Profiling in Pharmaceutical Analysis: A bri...
Aditi A Kokande, Sanket S Gite, Nikit S Thakare , Aniket B Bairagi, Shubham R Jadhav, Himmat D Sawan...
Formulation And Evaluation Of Gastroretentive Floating Tablet Of Atorvastatin Ca...
Toushiba Javed Khan , Sheikh Samir Md. Mustafa , Asra S. Shaikh, Zoya F. Shaikh, Mohammad Jawwad, Am...
Pharmacovigilance In The Digital Age...
Shruti Aher, Manoj Mahajan, Aman Upaganlawar, Chandrashekhar Upasani, ...
Niosomes Used In Treatment Of Cancer: A Review...
Sudarshan Kale, Shraddha vaishnav , Vinit khairnar , chaitali markand , ...
A Review: Formulation of Herbal Lozenges for Increasing platelet Counts ...
Lina Durbale, Vaibhav Jain, Bhagyashri Meshram, ...
More related articles
A Review: Formulation of Herbal Lozenges for Increasing platelet Counts ...
Lina Durbale, Vaibhav Jain, Bhagyashri Meshram, ...
An Introduction To Pharmaceutical Excipients Use In Soid Oral Formulation : A Re...
Rajeshwari G. Khairnar, Aniket T. Chavan, Rupali R. Tasgaonkar, ...
Concept And Recent Advancement In Tablet Coating Technologies: A Comprehensive R...
Shrikant S. Dongare, Mr. Dnyaneshwar S. Vyavhare, Dr. Megha T. Salve, ...
A Review: Formulation of Herbal Lozenges for Increasing platelet Counts ...
Lina Durbale, Vaibhav Jain, Bhagyashri Meshram, ...
An Introduction To Pharmaceutical Excipients Use In Soid Oral Formulation : A Re...
Rajeshwari G. Khairnar, Aniket T. Chavan, Rupali R. Tasgaonkar, ...
Concept And Recent Advancement In Tablet Coating Technologies: A Comprehensive R...
Shrikant S. Dongare, Mr. Dnyaneshwar S. Vyavhare, Dr. Megha T. Salve, ...