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Abstract

Blood group detection is an essential part of healthcare, especially in situations like blood transfusions, organ transplants, and medical emergencies. Traditionally, blood groups are identified using laboratory-based methods that require blood samples, chemical reagents, and trained personnel. These methods, while effective, can be time-consuming, invasive, and prone to human error.In recent years, advancements in technology have introduced artificial intelligence (AI) techniques that can detect blood groups through fingerprints, providing a non-invasive, faster, and more accurate alternative. AI-based finger machines analyze patterns and features in fingerprints to predict blood group types without the need for drawing blood.This review paper explores both traditional and AI-based methods for blood group detection. It explains how AI finger machines work, compares them with old methods, discusses their advantages and limitations, and highlights potential applications in hospitals, blood donation camps, and personal healthcare monitoring. The paper also looks at the future prospects of integrating AI blood detection systems with modern healthcare technology to improve efficiency and accessibility.

Keywords

Artificial Intelligence (AI), Blood Group Detection, Finger Recognition, Machine Learning, Biomedical Device, Deep Learning, Image Processing, Sensor Technology

Introduction

Blood is a vital component of the human body, responsible for transporting oxygen, nutrients, and removing waste. Blood group identification is very important in healthcare, especially during blood transfusions, organ transplants, pregnancy, and emergency treatments. If a person receives incompatible blood, it can lead to serious health problems or even death [1]. Traditionally, blood group detection involved laboratory-based methods like the slide test, tube test, and gel card method. These methods require blood samples, reagents, and trained personnel. Although accurate, they are time-consuming, invasive, and sometimes prone to human error [2]. With the development of technology, artificial intelligence (AI) has started to play a role in healthcare diagnostics. AI can analyze complex patterns and large datasets, making medical procedures faster and more accurate [3]. One of the recent innovations is the AI-based finger machine, which can predict blood groups by analyzing fingerprint patterns. This method is non-invasive, fast, and user-friendly, reducing the need for drawing blood and laboratory testing [4] The main goal of this review is to explain how AI finger machines work, compare them with traditional blood group detection methods, discuss their advantages and limitations, and highlight their applications in modern healthcare. This paper also explores the future prospects of AI-based blood group detection technology.

 

 

 

Fig no 1 “Blood Group Types and Universal Donor/Receiver Chart”

 

  1. Concept of Blood Groups

Blood groups are classifications of blood based on the presence or absence of specific antigens and antibodies in red blood cells and plasma. Understanding blood groups is very important because compatible blood transfusions save lives, while incompatible transfusions can cause serious reactions [5].

1.1 ABO Blood Group System

  • The ABO system is the most widely known blood group classification. It divides blood into four types:
  • Type A: Has A antigen on red blood cells and anti-B antibodies in plasma.
  • Type B: Has B antigen on red blood cells and anti-A antibodies in plasma.
  • Type AB: Has both A and B antigens on red blood cells and no antibodies in plasma. It is known as the universal recipient.
  • Type O: Has no antigens on red blood cells and both anti-A and anti-B antibodies in plasma. It is known as the universal donor [6].

1.2 Rh Blood Group System

The Rh system classifies blood based on the presence or absence of the Rh antigen (also called D antigen):

  • Rh-positive (+): Blood cells have the Rh antigen.
  • Rh-negative (-): Blood cells do not have the Rh antigen [7].

Combining the ABO and Rh systems gives eight possible blood types: A+, A-, B+, B-, AB+, AB-, O+, and O-.

1.3 Importance of Blood Group Knowledge

  • Ensures safe blood transfusions.
  • Helps in organ transplantation compatibility.
  • Important for pregnancy to avoid Rh incompatibility between mother and fetus.
  • Useful in forensic medicine and personalized healthcare [8].

Understanding these systems is the foundation for both traditional and AI-based blood group detection methods. In the following sections, we will discuss how these methods work and their processes.

 

 

 

Fig no 2: Fingerprint Pattern

 

  1. Traditional Blood Group Detection Methods

Before the invention of AI-based detection systems, blood groups were determined using manual laboratory methods. These methods are still widely used in hospitals and blood banks because they are accurate and reliable.

 

 

 

Fig no 3: Traditional Blood Group Detection Methods

 

2.1 Slide Test Method

The slide test is a quick and simple method for blood group detection.

Process Steps:

  1. Place a drop of blood on a clean slide.
  2. Add a drop of anti-A, anti-B, and anti-Rh sera to separate spots.
  3. Mix gently and observe for agglutination (clumping).
  • Clumping with anti-A → Blood group A
  • Clumping with anti-B → Blood group B
  • Clumping with both → Blood group AB
  • No clumping → Blood group O
  1. Observe Rh factor using anti-Rh serum [9].

Advantages:

Quick and simple.

Requires minimal equipment.

Limitations:

Less accurate than tube method.

Requires careful observation; human error possible.

2.2 Tube Test Method

The tube test is more accurate and commonly used in laboratories.

Process Steps:

  1. Collect a small sample of blood in test tubes.
  2. Add anti-A, anti-B, and anti-Rh sera to separate tubes.
  3. Mix gently and centrifuge if needed.
  4. Observe for agglutination to identify the blood group and Rh type [10].

Advantages:

More accurate than slide test.

Can detect weak reactions.

Limitations:

Requires laboratory setup.

Time-consuming compared to slide test.

 

2.3 Gel Card Method

The gel card method is a modern version of traditional methods and widely used in blood banks.

Process Steps:

  1. Blood is added to gel card microtubes containing reagents.
  2. The card is centrifuged.
  3. Agglutination patterns indicate the blood group and Rh factor [11].

Advantages:

Highly accurate and reliable.

Minimal human error.

Can be automated for large-scale testing.

Limitations:

More expensive than slide and tube tests.

Requires specialized equipment.

2.4 Summary

Traditional methods are effective and widely accepted but are time-consuming, require blood samples, and sometimes need skilled personnel. These limitations led to the development of AI-based, non-invasive blood group detection systems, which are discussed in the next section [12].

  1. AI-based Finger Machine for Blood Group Detection

AI-based finger machines are a modern, non-invasive technology that can predict a person’s blood group by analyzing fingerprint patterns. This technology uses sensors, artificial intelligence, and machine learning algorithms to make accurate predictions without the need for blood samples [18].

 

 

 

 

 

Fig no: 4 Al-based Finger Machine for Blood Group Detection

 

3.1 Working Principle

  1. Fingerprint Scanning: The machine uses a high-resolution sensor to capture the fingerprint image.
  2. Image Processing: AI algorithms process the fingerprint to identify unique patterns, ridges, and loops.
  3. Pattern Matching: The processed fingerprint is compared with a database of known fingerprints and their associated blood groups.
  4. Prediction: The AI predicts the person’s blood group and Rh type based on correlations found in the database.
  5. Display Results: The blood group is displayed on the machine screen within seconds [19].

3.2 Process Steps (Short)

  1. Place the finger on the scanner.
  2. The sensor captures the fingerprint image.
  3. AI software analyzes fingerprint features.
  4. The machine compares patterns with its database.
  5. Blood group and Rh type are predicted and displayed.

3.3 Components of AI Finger Machine

  • Fingerprint Sensor: Captures the fingerprint image.
  • AI Software/Algorithm: Processes and analyzes patterns.
  • Database: Stores fingerprint patterns and blood group correlations.
  • Display Unit: Shows the result to the user.

3.4 Advantages Over Traditional Methods

  • Non-invasive: No blood sample required.
  • Fast: Results in a few seconds.
  • User-friendly: Easy to use, even by non-specialists.
  • Portable: Can be used in blood donation camps, hospitals, and remote areas [20].

3.5 Limitations

  • Accuracy depends on database size: Small or incomplete databases may reduce accuracy.
  • Initial cost is high: Machines and software development can be expensive.
  • Technical errors: Fingerprint smudges or sensor issues may affect results.

AI-based finger machines are an innovative alternative to traditional blood group detection methods, combining speed, safety, and convenience. In the next section, we will compare traditional and AI methods to highlight the differences [21].

  1. Comparison of Old vs. New Methods

Blood group detection has evolved from traditional laboratory methods to modern AI-based finger machines. Comparing these methods helps understand the advantages, limitations, and suitability of each approach.

4.1 Comparison Table

 

 

 

 

4.2 Explanation of Comparison

Sample Required & Invasiveness: Traditional methods need blood collection, which can be uncomfortable or risky. AI finger machines do not require blood, making them painless and safer [22].

  • Time Efficiency: Traditional methods take minutes, whereas AI-based machines provide results in seconds, which is useful in emergencies or large-scale testing [23].
  • Accuracy & Human Error: Traditional methods rely on human observation, so errors may occur. AI methods reduce human error but require a large, accurate database to maintain precision [24].
  • Equipment & Portability: Traditional methods require laboratory setups, limiting field use. AI machines are compact and portable, ideal for blood donation camps and rural areas [25].
  • Cost & Scalability: While AI machines have a higher initial cost, they can test more people quickly, making them cost-effective in the long run [26].

In summary, AI-based finger machines provide a faster, safer, and more convenient alternative to traditional methods. However, traditional laboratory methods are still reliable and widely used, especially in controlled medical settings.

  1. Advantages of AI Finger Machine

AI-based finger machines for blood group detection offer many benefits compared to traditional methods. These advantages make them suitable for hospitals, blood donation camps, and personal healthcare monitoring [27].

5.1 Non-Invasive Method

Unlike traditional methods, no blood sample is needed.

Reduces pain, risk of infection, and discomfort for the patient.

5.2 Fast Results

Provides blood group and Rh type within seconds.

Useful in emergencies where time is critical.

5.3 User-Friendly

Requires minimal training to operate.

Can be used by nurses, volunteers, or non-specialized staff.

5.4 Portable and Convenient

Compact design allows use in remote areas, mobile blood donation camps, and small clinics.

No need for a fully equipped laboratory [28].

5.5 Accurate and Reliable

AI analyzes complex fingerprint patterns to predict blood groups.

Reduces human error compared to manual methods.

5.6 Cost-Effective in the Long Run

Although initial investment is high, AI machines reduce labor costs and testing time over time.

Suitable for high-volume blood testing in hospitals or blood banks [29].

5.7 Hygienic and Safe

Non-contact process reduces the chance of cross-contamination.

Safe for multiple users in blood donation drives or hospital settings.

5.8 Ideal for Large-Scale Screening

Can quickly test many people in a short time.

Useful for blood donation camps, school health programs, and community health check-ups [30].

In summary, the AI finger machine is faster, safer, and more convenient than traditional methods, making it a valuable tool in modern healthcare.

  1. Disadvantages and Challenges of AI Finger Machine

While AI-based finger machines offer many advantages, they also have some limitations and challenges that need to be considered [31].

6.1 Initial High Cost

The machines and AI software require a significant investment.

Smaller clinics or rural areas may find it expensive to adopt initially.

6.2 Dependence on Database

AI predicts blood groups by comparing fingerprints with a pre-existing database.

If the database is small or incomplete, accuracy may decrease.

6.3 Technical Issues

Fingerprint smudges, dirt, or injuries can affect scanning.

Sensor malfunctions or software glitches may lead to incorrect results [32].

6.4 Limited Research in Diverse Populations

Most AI models are trained on specific populations.

Accuracy may vary for different ethnic groups or age categories, requiring further research.

6.5 Training and Maintenance

Operators need basic training to handle the machine properly.

Regular software updates and maintenance are necessary to ensure accuracy.

6.6 Privacy Concerns

Fingerprints are biometric data, which may raise data security and privacy issues.

Proper data protection measures are needed to prevent misuse [33].

6.7 Not a Complete Replacement for Traditional Methods

In critical medical situations, laboratory confirmation may still be required.

AI finger machines are currently used as a supplementary tool rather than a full replacement.

In summary, while AI-based finger machines are innovative and convenient, addressing these challenges is necessary for wider adoption and reliable use in healthcare systems.

  1. Uses / Applications of AI Finger Machine

AI-based finger machines for blood group detection have a wide range of applications in healthcare and related fields. These uses make the technology practical, efficient, and beneficial for both medical professionals and the general public [34].

7.1 Hospitals and Clinics

Used for quick blood group determination during emergencies.

Helps doctors and nurses avoid delays in blood transfusions.

Reduces manual work and dependency on laboratory staff.

7.2 Blood Donation Camps

Can screen donors quickly and safely without taking blood samples.

Ensures that donated blood is compatible and reduces the risk of errors.

Speeds up the process for large numbers of donors.

7.3 Emergency Medical Services

In ambulances or emergency rooms, AI machines provide instant blood group results.

Useful in accident cases or urgent surgeries where time is critical [35].

7.4 Personal Health Monitoring

Can be integrated with personal health devices or apps for self-monitoring.

Useful for individuals who need frequent blood group checks, like patients with chronic conditions.

7.5 Research and Forensic Science

AI finger machines help in medical research by collecting large-scale blood group data.

Can be used in forensic investigations where blood samples are limited or unavailable.

7.6 Remote and Rural Healthcare

Portable AI machines allow blood group testing in rural areas with limited laboratory facilities.

Beneficial in mobile health camps and community health programs.

7.7 Integration with Smart Healthcare Systems

Can be connected to hospital management systems or electronic health records for automatic data updating.

Helps in tracking blood group information for patients efficiently [36].

In summary, AI-based finger machines have diverse applications that improve speed, safety, and accessibility in healthcare and related fields.

  1. Future Prospects of AI Finger Machine

The use of AI-based finger machines for blood group detection is still evolving, and its future holds many exciting possibilities. As technology improves, these machines could become even more accurate, affordable, and widely available [37].

8.1 Integration with Wearable Devices

In the future, AI blood detection could be integrated into smartwatches or wearable health devices.

People could check their blood group anytime without visiting a hospital.

8.2 Smart Hospitals and Telemedicine

AI finger machines could be connected to hospital databases for real-time patient monitoring.

Doctors could access blood group information remotely, improving telemedicine services [38].

8.3 Large-Scale Deployment

Portable machines could be used in schools, workplaces, and community health programs for mass blood group screening.

Could help maintain accurate population blood group databases.

8.4 Improved Accuracy with Big Data

With larger fingerprint databases and advanced AI algorithms, prediction accuracy will improve.

AI could also identify rare blood types more reliably.

8.5 Combination with Other Health Diagnostics

AI machines could evolve to detect other health conditions from fingerprints, such as blood sugar levels or genetic markers.

This will make health monitoring faster and non-invasive [39].

8.6 Cost Reduction and Accessibility

As technology becomes cheaper, AI finger machines could be affordable for small clinics and rural healthcare centers.

Could make blood group testing accessible to everyone.

8.7 Research and Development

Continuous R&D can improve machine sensors, AI algorithms, and database management.

Could lead to fully automated, highly reliable, and user-friendly systems in the near future [40].

In summary, the future of AI-based finger machines is promising. They are expected to become faster, more accurate, affordable, and integrated into daily healthcare systems, revolutionizing blood group detection.

CONCLUSION

Blood group detection is a critical aspect of healthcare, essential for safe blood transfusions, organ transplants, and emergency medical treatments. Traditional methods like the slide test, tube test, and gel card method are reliable but time-consuming, invasive, and require skilled personnel [41].The development of AI-based finger machines has introduced a fast, non-invasive, and user-friendly alternative. These machines use fingerprint patterns, AI algorithms, and databases to predict blood groups accurately within seconds [42]. Compared to traditional methods, AI machines are safer, more convenient, portable, and suitable for large-scale screening [43].While AI finger machines have challenges such as high initial costs, dependence on database quality, and privacy concerns, ongoing research and technological advancements are addressing these issues [44]. Their applications in hospitals, blood donation camps, emergency services, personal health monitoring, and research demonstrate their potential to transform healthcare [45].In the future, AI-based blood group detection is expected to become more accurate, affordable, and widely integrated with wearable devices and smart healthcare systems. Overall, this technology represents a significant advancement in medical diagnostics, offering efficiency, safety, and accessibility to both healthcare providers and patients.

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Photo
Krushi Pradhan
Corresponding author

Department of pathology , KVNNSPS's Institute of Pharmaceutical Education and Research

Photo
Pratik Bhabad
Co-author

Department of Pathology, Department of pathology , KVNNSPS's Institute of Pharmaceutical Education and Research

Photo
Janvi Patil
Co-author

Department of Pathology,Department of pathology , KVNNSPS's Institute of Pharmaceutical Education and Research

Krushi Pradhan, Pratik Bhabad, Janvi Patil, Varsha Chavan, Blood Group Detection Using Artificial Intelligence, Int. J. of Pharm. Sci., 2026, Vol 4, Issue 2, 2311-2322. https://doi.org/10.5281/zenodo.18649562

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