*1Student Department of Pharmaceutical Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, India
2Assistant Professor Department of Pharmaceutical Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, India
3Principal Department of Pharmaceutical Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, India
Azoles are heterocyclic chemicals that were first identified in late 1960 and make up the largest class of currently accessible antifungal medications. A particular chemical element that gives azoles their activity is the imidazole ring. Triazoles are made by making a small alteration to this ring, and derivatives of triazoles have been found to have equal or better actions as well as fewer negative effects. It follows that the discovery of biological activity in benzimidazole/benzotriazole compounds is not unexpected. Due to the extensive research on benzimidazole, the focus of this review is on defining the role of benzotriazole derivatives in biomedical research, highlighting their diverse biological characteristics, the mechanism of action, and Structure Activity Relationship (SAR) studies for a variety of antimicrobial, antiparasitic, and even antitumor, cholesterol-lowering agents.
Aniket Dandge*, Shubhangi Manikpuriya, Gajanan Sanap, Benzotriazole Derivatives And Its Pharmacological Activity, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 948- 957. https://doi.org/10.5281/zenodo.10443937