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Abstract

Suppositories are pharmaceutical dosage forms that hold a crucial place in the realm of drug delivery. Suppositories are the dosage form inserted into body cavity, mainly rectum and vagina to deliver the drug into the systemic circulation. Suppositories can be taken by patients who are unable to take medicine orally due to nausea and vomiting, and neurological disorder. Suppositories are used over other dosage form because it comes in different shapes and sizes. Suppositories are one of the very feasible modes of administration for medication. It can be prepared by using various bases like cocoa butter, PEG, and fatty base as main ingredients. It can be prepared by using hand rolling, compression molding, fusion molding, and automatic Mold method. Evaluation tests like Uniformity of weight, Content Uniformity test, Melting point determination test, General appearance test, Assay of active contents, Liquefaction time, Breaking test, Disintegration test, Dissolution test.

Keywords

Suppositories; Suppository Bases; Preparation methods; Characteristics

Reference

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Photo
N Deekshitha Reddy
Corresponding author

Sri Venkateswara University College of pharmaceutical sciences

Photo
K. Muniraja Lakshmi
Co-author

Sri Venkateswara University College of pharmaceutical sciences

K. Muniraja Lakshmi, N. Deekshitha Reddy, A Review On Suppositories, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 2, 668-675. https://doi.org/10.5281/zenodo.10701894

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