Department of Pharmaceutical Chemistry, Visveswarapura Institute of Pharmaceutical Sciences, Bangalore, Karnataka, India 560070
Chalcones are the simple chemical structures consisting of ?, ? unsaturated carbonyl group attached to aromatic or heterocyclic rings. These are naturally occurring compounds and even can be synthesized via various chemical reactions in laboratory conditions. From many decades they attracted the attention of researchers due to their numerous biological activities and clinical potentials, simple method of preparation and for their utility as scaffolds for the synthesis of many pharmacologically active heterocyclic compounds like pyrimidines, pyrazoles, pyridines etc. by simple cyclization and addition reactions. Multiple aspects of chalcones are summarized comprehensively, reviewed critically in this review including development of new synthetic strategies using various methods and catalysts.
Bhargav A. , Yashwanth R. , Pavan Kumar C. , A Comprehensive Review On Synthetic Strategies Of Chalcones, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 1, 238-247. https://doi.org/ 10.5281/zenodo.10517190