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Abstract

Sesame is a plant. The diploid is dicotyledonous. It is the oldest oil seed crop. It has areas for its oil. vitamins and minerals. Sesame is valuable. Dry seeds, feed, and cover crop are grown for food. There are leaves and young branches beside the other. Like flowers, parts of the plant are useful. There are treatments for cancer, alopecia and constipation. The leaves are having antifungal activity. It was used in many diseases. There are infections for the urinary system. There is a lot of large land for farming. There is a wide demand–supply gap for sesame. There are various biotics that constrained production. Less productivity is caused by abiotic stresses.Attempts are made for the terms of seed yield.spreading awareness about sesame oil.There are other uses. Sesame oil has anti-aging properties.There are a number of drugs known as sesamol.The vegetable oils have a long shelf.life. The sesame seed oil is rich in Omega 6.Omega 3 is missing. There is a need.Omega 3 and alpha are Omega 3 acids.There are linolenic acids with the help of desaturase.There are pathways for improvement of quality.

Keywords

Sesame, feed, antifungal activity, Omega3 fatty acids, desaturase, quality

Introduction

Sesame seeds date back as early as 1600 BC. They are the oldest condiments in existence. Sesame. Sesamum indicum L. is owned by the family. It is widely cultivated in the tropical. There are about 36 species in parts of Africa and Asia. The wild species are located. There are a few in India. The thing. Ethiopia was the original home of this crop. India is the major producer of sesame. China and Sudan make up more than half of the world. Production India is ranked first in the world. The area and production of sesame seeds. Oil from sesame can be found in a wide range of seasons. It was honoured as a rich food because of its high quality. Good quality and stability. It can be used many different ways. The plant is depicted in a figure. It is not the same as other vegetables. The oils have high nutrition and therapeutic qualities. The health benefits of sesame include values. Antihypersensitive, antioxidative and anticancer. ds are used in the production of food and in other food products.

Figure. sesame plant

From the beginning. It's known that sesame has a chemical composition. The seeds contain a high percentage of oil. Carbohydrate and ash make up 13. 5% and 5% of the total. It was The. Stable oxidation can be attributed. To its anti-oxidant lignans. They have tocopherols [6]. Sesamin had a 1. 1%. There are traces of sesamol that contribute. There are unique properties of sesame oil. In the east. sesame has been in parts of the world. It is considered a health food. Energy and prevention of aging are related. The oil has lots of money. It has a mild amount of the unsaturated fat acids. It is said to be a plant's dream crop. Sesame has a great genetic diversity. The rich source of calcium. The amount of phosphorous is about 0. 7%. It contains sesame. There is ample amounts of oleic and linoleic. The acids are palmitic and stearic. They make up 98% of the total fat.

Varieties and Genetic Diversity

There are varieties and genetic diversity. There is a nutty taste in sesame seeds. It is delicate with a small crunch. They vary in size. From small to large and come in many different colors. Depending on the variety, including white, yellow, and black. There are grey, brown and red. The seeds from the northeast. Those from the eastern region are brown in color. Red or reddish is the color of black and from the south. There is a brown color. White seeds come from other regions. White. On an average, black seeds contain 45% and 47. 8%. There are oil and oil and oil. The sesame seed coat is black.

Table 1: Diversity of sesame seeds

Colour

Seed Colour

USA

Light brown

Palestine

Brown & white

Portugal

Grayish white

Turkey

Light brown

Bulgaria

White & brown

Korea

White & brown

Brazil

Dark grey

India

White & grey

Venezuela

Grayish white

Ethiopia

Light brown

Tanzania

Grayish white

China

Black

Egypt

Light brown

 The countries that impart are America, Mexico, Guatemala and Venezuela. Sixty percent to the continent's production. There are samples of seeds K analysed from different states of India. Random amplified by Venkataramana Bhat and his team. TheRAPD is a technique that uses polymorphic DNA. The results showed up. The level of genetic diversity indicated the nativity. The crop was shown byRajasthan and the north eastern states. There is a maximum of diversity. The area under the world There are 6 million hectares of sesame. of the crop is used for oil. There are seven different varieties of sesame. There are different growing regions found in India. There are two from the state of UP, CST 2002 and MT 34. TKG 22 is from Maharashtra. From Assam, B 67 and Rama. West Bengal. Two sections of Sesamum are found in India. Both S. laciniatum and S. prostratum are related. Another part includes. Wild gingelly of is what it is called by locals. It's called Malabar.

Extraction of Oil

The industrialization of sesame oil is very important. There are food, cosmetics and pharmaceutical purposes. There is a final product. The quality and environmental aspects are important. There are considerations for a good process. There are several sesame oil productions involves mechanical processes. Then solvent extraction using organic liquids. The solvent is recovered by distillation. It's very critical. It is an alternative process that uses pressurized water. The use of liquid organic solvents can be minimized with fluids. The weight of highly stable sesame seed makes it give about 50%. After the oil has been produced. Lignan content contributes to 32. 23% of the total. The extract is made using solvent. In case of something. The lignan content has been found to be supercritical. It was 1. 5 to 3. 5 percent. The main lignans are 10% of the total. There is an unsaponifiable matter in sesame oil.

Solvent extraction

The solute is distributed between two phases. The density difference causes them to be in contact with each other. The principle of solvent extraction. Unroasted in the process. The seeds are first pressed. A solvent is being used. sesame seeds are prepared with polar. More stable oil is generated by solvent and effective seed crushing. Heptaneisopropanol shows to yield more stable oil than n-Hexane. The stability of the environment. The oil is influenced by the method. The yield of solvent is possible. The oil is from the seeds. The disadvantages related to solvent extraction are complex. The process is not suitable for small scale processing. One of the biggest problems is the management of organic solvent.

Supercritical extraction

The principle behind supercritical extraction is that, near the critical point of the solvent, its properties change rapidly with slight variations in the pressure invo Supercritical extraction of sesame is usually carried out using carbon dioxide and propane as solvents. Extraction of oil using carbon dioxide includes 313 to 333 K temperature range, pressure variation of 19 to 25 MPa and constant flow rate of 3cm3 /min and that using propane includes 303 to 333K range of temperature, pressures from 8 to 12 MPa and a constant flow rate of 0. 8cm3 /min.

As the pressure and CO2 flow. The time can be improved and the rate increased. The process can be reduced. The sesame seeds have seeds. The process requires the dried and milling of specified particles. diameter This process is more friendly to the environment. You should be able to extract it faster. There is a disadvantage in this process. Difficult in understanding the phase of the solvent. The solvent and oil have different behavior

Medical Uses

Regulating cholesterol

It's important to identify the components that regulate cholesterol levels. Any natural substance. It has gained therapeutic importance due to interfering in the cholesterol metabolism. There is a major. Lignan is present in sesame seeds and is related to a series of biochemical actions in both humans and animals. They are animals. The increase in Dietary Sesamin and Episesamin has been significant. The expression of genes for mitochondrial and peroxisomal fatty acid. carnitine palmitoyltransferase and acyl- coA are oxidation enzymes. Acyl-coA oxidase, 3-hydroxyacyl-coA dehydrogenase, is a dehydrogenase. The enoyl- CoA hydratase and 3-ketoacyl-CoA thiolase are increasing. Enhanced ketone is responsible for the activity of fatty acid oxidation. The body is produced. This metabolism accounts for the fat in the body. The cholesterol level is being lowered. Sesamin increases the activity. The expression of a malic enzyme has lipogenic activity. Hypo cholesterolemic action is greatly increased by alpha- tocopherol. It doesn't affect the concentration. The cholesterol level in the person.

Benefits in regulation of blood pressure

It's impressive that sesame oil is rich in poly. Sulfur and vitamins E and PUFA greatly reduce. When compared to drugs for hypertension. The article is titled. The wall thickness and area is decreased by Sesamin feeding. The superior mesenteric arteries. It decreases histological. The tunica intima and fibrinoid are damaged. A feature not observed in normal is the degradation of the arterial wall. The diet Sesamin is useful for prophylactic treatment. The development of cardiac hypertrophy

Antioxidant properties

Sulfur, sesamolinol, is one of the important antioxidants. The fats include the Low Density Liposprotein arteriosclerosis is caused by LDL which are believed to promote. The integrity of the body's tissues. Antioxidant lignans have shown. Hypocholesterolemic and immunomodulatory effects. The fat protects the body from harmful oxidation. The compounds. The sesame seed oil has tocopherols. They have the same activity as Vitamin E.

Sesame in Ayurveda

The most esteemed oil is sesame oil. There's oil in ayurveda. It is known for its healing properties. It has a reputation as a sedative in Tibetan medicine. The Chinese system of medicine has been around for thousands of years. Sesame is a part of ayurveda. It is known that it can cure Tridoshas. Abhyanga is a type of massage. The oil is rubbed on the skin to improve energy flow. The body needs to be free of impurities. sesame oil is considered to be a part of ayurveda. It can also be applied to nostrils. Anxiety and insomnia can be alleviated. Premenstrual pain. The oil can be applied to the syndrome. The area of the abdomen. There is a traditional system of medicines. It's known that sesame can cure a lot of things. Is it possible that there is impotency.

Other Uses

Nosocomial infections are caused by gram negative bacteria. The concern is in the developing countries. sesame is related to this problem. The meals show the presence of anti-microbial peptides. A major peptide is analyzed through HPLC and mass spectrometric analysis. There is approximately 5. 8 kDa in both white and black cultivars. It has bactericidal activities and is identified as an antimicrobial peptide. The Klebsiella species is responsible for human infections. It proves to be a potential method for hospital infection control. To decrease the resistance to synthetic antibiotics. Sesamin is a non-fat part of sesame seed oil. Dihomo-gamma-linolenic can be caused by desaturase activity. acid, which deracinates arachidonic acid. Pro inflammatory mediators are decreased. Diets are used sesame seed oil and quilA emulsifies fat. Decrease the levels of dienoic eicosanoids with a cumulative effect. The levels of IL-10 were marked increased. There is a capacity of endurance.

CONCLUSION

India is the largest producer of sesame, which has high nutritive and therapeutic qualities. Sesame is a rich source of macro and micro nutrients including proteins, dietary lignans, vitamins, calcium, phosphorous and others but not many values added products other than sesame oil has been developed (Table 3). When analysed, it is found that the by-products obtained extraction of oil contains comparatively high nutritive value and in future, can be consumed as a supplement for protein rich food. With the advancement in technology sesame oil when blended with rice bran or Soya or other oil can be of a great advantage with respect to nutritional aspects. Nutraceuticals and pharmaceutical products of sesame can decrease the risk of neurological, dermatological, cancer and heart disease. The future of sesame lies in its by-products and biodiesel application.

ACKNOWLEDGEMENTS

The authors are grateful to the Principal, Sri Jayachamarajendra College of Engineering, Mysore and the Head of the Department, Department of Biotechnology for providing facilities for the research work. They also thank Ms. Thiagarajan Agro Products, (P) Ltd. (Sastha oil), Madurai for their support.

REFERENCES

  1. Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore-641003,Tamilnadu, India.
  2. Saydut A, Duz MZ, Kaya C, Kafadar AB, Hamamci C (2008) Transesterified sesame (Sesamum indicum L. ) seed oil as a biodiesel fuel. Bioresour Technol 99: 6656-6660.
  3. Hiremath SC, Patil CG, Patil KB, Nagasampige MH (2007) Genetic diversity of seed lipid content and fatty acid composition in some species of Sesamum L. (Pedaliaceae). Afr J Biotechnol 6: 539-54
  4. https://www. google. com/imgres
  5. Bisht IS, Mahajan RK, Loknathan TR, Agrawal RC (1998) Diversity in Indian sesame collection and stratification of germplasm accessions in different diversity groups. Genet Resour Crop Ev 45: 325-335.
  6. Banerjee PP, Kole PC (2009) Analysis of genetic architecture for some physiological characters in sesame (Sesamum indicum L. ). Euphytica 168: 11-22.
  7. Elleuch M, Besbes S, Roiseux O, Blecker C, Attia H (2007) Quality characteristics of sesame seeds and by-products. Food Chem 103: 641-650.
  8. Johnson LA, Suleiman TM, Lusas EW (1979) Sesame protein: a review and prospectus. J Am Oil Chem Soc 56: 463-468.
  9. Kamal-Eldin A, Appelqvist L (1995) The effects of extraction methods on sesame oil stability. J Am Oil Chem Soc 72: 967-969.
  10. Alam MS (2007) Fats and Oils Chemistry: Factors Affecting Crude Oil Quality. Presented to the Vegetable Oils Extraction Short Course, Texas A&M Food Protein R&D Center, College Station, Texas.
  11. https://www. google. com/imgres
  12. Corso MP, Fagundes-Klen MR, Silva EA, Filho LC, Santos JN, et al. (2010) Extraction of sesame seed (Sesamun indicum L. ) oil using compressed propane and supercritical carbon dioxide. The Journal of Supercritical Fluids 52: 56-61.
  13. Doker O, Salgin U, Yildiz N, Aydogmu? M, Çalimli A (2009) Extraction of sesame seed oil using supercritical CO2 and mathematical modeling. J Food Eng 97: 360-366.
  14. Morris JB (2002) Food, industrial, nutraceutical, and pharmaceutical uses of sesame genetic resources. Trends in new crops and new uses 153–156.
  15. Penalvo JL, Hopia A, Adlercreutz H (2006) Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice. Eur J Nutr 45: 439-444.
  16. Ashakumary L, Rouyer I, Takahashi Y, Ide T, Fukuda N, et al. (1999) Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat. Metabolism 48: 1303-1313. 17) Ogawa H, Sasagawa S, Murakami T, Yoshizumi H (1995) Sesame lignans modulate cholesterol metabolism in the stroke-prone spontaneously hypertensive rat. Clin Exp Pharmacol Physiol Suppl 22: S310-S312.
  17. Matsumura Y, Kita S, Tanida Y, Taguchi Y, Morimoto S, et al. (1998) Antihypertensive effect of sesamin. III. Protection against development andmaintenance of hypertension in stroke- prone spontaneously hypertensive rats. Biol Pharm Bull 21: 469-473.
  18. Kita S, Matsumura Y, Morimoto S, Akimoto K, Furuya M, et al. (1995) Antihypertensive effect of sesamin. II. Protection against two-kidney, one-clip renal hypertension and cardiovascular hypertrophy. Biol Pharm Bull 18: 1283-1285.
  19. Hemalatha S, Ghafoorunissa (2004) Lignans and tocopherols in Indian sesame cultivars. J Am Oil Chem Soc 81: 467-470.
  20. https://www. researchgate. net/figure/Expelling-process-flow-chart_fig1_290759771
  21. Yamada Y, Obayashi M, Ishikawa T, Kiso Y, Ono Y, et al. (2008) Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice. J Nutr Sci Vitaminol (Tokyo) 54: 117-123.
  22. Collinge W, American Holistic Health Association (1996) The American Holistic Health Association Complete Guide to Alternative Medicine. Warner Books, New York, USA. 24) Costa FT, Neto SM, Bloch C Jr, Franco OL (2007) Susceptibility of human pathogenic bacteria to antimicrobial peptides from sesame kernels. Curr Microbiol 55: 162-166.
  23. Chavali SR, Zhong WW, Forse RA (1998) Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice. Prostaglandins Leukot Essent Fatty Acids 58: 185-191.
  24. Chavali SR, Zhong WW, Utsunomiya T, Forse RA (1997) Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. Int Arch Allergy Immunol 114: 153-160.
  25. Balan V, Rogers CA, Chundawat SPS, da Costa Sousa L, Slininger PJ, et al. (2009) Conversion of Extracted Oil Cake Fibers into Bioethanol Including DDGS, Canola, Sunflower, Sesame, Soy, and Peanut for Integrated Biodiesel Processing. J Am Oil Chem Soc 86: 157-165.
  26. http://faostat. fao. org/site/339/default. aspx
  27. Moazzami AA, Kamal-Eldin A (2006) Sesame seed is a rich source of dietary lignans. J Am Oil Chem Soc 83: 719-723.
  28. El Tinay AH, Khattab AH, Khidir MO (1976) Protein and oil compositions of sesame seed. J Am Oil Chem Soc 53: 648-653.
  29. Supercritical Fluids (SCF) and supercritical Fluid Extraction (SFE) prepared at thermodynamics research laboratory, Department of Chemical Engineering.

Reference

  1. Department of Plant Biotechnology, Centre for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore-641003,Tamilnadu, India.
  2. Saydut A, Duz MZ, Kaya C, Kafadar AB, Hamamci C (2008) Transesterified sesame (Sesamum indicum L. ) seed oil as a biodiesel fuel. Bioresour Technol 99: 6656-6660.
  3. Hiremath SC, Patil CG, Patil KB, Nagasampige MH (2007) Genetic diversity of seed lipid content and fatty acid composition in some species of Sesamum L. (Pedaliaceae). Afr J Biotechnol 6: 539-54
  4. https://www. google. com/imgres
  5. Bisht IS, Mahajan RK, Loknathan TR, Agrawal RC (1998) Diversity in Indian sesame collection and stratification of germplasm accessions in different diversity groups. Genet Resour Crop Ev 45: 325-335.
  6. Banerjee PP, Kole PC (2009) Analysis of genetic architecture for some physiological characters in sesame (Sesamum indicum L. ). Euphytica 168: 11-22.
  7. Elleuch M, Besbes S, Roiseux O, Blecker C, Attia H (2007) Quality characteristics of sesame seeds and by-products. Food Chem 103: 641-650.
  8. Johnson LA, Suleiman TM, Lusas EW (1979) Sesame protein: a review and prospectus. J Am Oil Chem Soc 56: 463-468.
  9. Kamal-Eldin A, Appelqvist L (1995) The effects of extraction methods on sesame oil stability. J Am Oil Chem Soc 72: 967-969.
  10. Alam MS (2007) Fats and Oils Chemistry: Factors Affecting Crude Oil Quality. Presented to the Vegetable Oils Extraction Short Course, Texas A&M Food Protein R&D Center, College Station, Texas.
  11. https://www. google. com/imgres
  12. Corso MP, Fagundes-Klen MR, Silva EA, Filho LC, Santos JN, et al. (2010) Extraction of sesame seed (Sesamun indicum L. ) oil using compressed propane and supercritical carbon dioxide. The Journal of Supercritical Fluids 52: 56-61.
  13. Doker O, Salgin U, Yildiz N, Aydogmu? M, Çalimli A (2009) Extraction of sesame seed oil using supercritical CO2 and mathematical modeling. J Food Eng 97: 360-366.
  14. Morris JB (2002) Food, industrial, nutraceutical, and pharmaceutical uses of sesame genetic resources. Trends in new crops and new uses 153–156.
  15. Penalvo JL, Hopia A, Adlercreutz H (2006) Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice. Eur J Nutr 45: 439-444.
  16. Ashakumary L, Rouyer I, Takahashi Y, Ide T, Fukuda N, et al. (1999) Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat. Metabolism 48: 1303-1313. 17) Ogawa H, Sasagawa S, Murakami T, Yoshizumi H (1995) Sesame lignans modulate cholesterol metabolism in the stroke-prone spontaneously hypertensive rat. Clin Exp Pharmacol Physiol Suppl 22: S310-S312.
  17. Matsumura Y, Kita S, Tanida Y, Taguchi Y, Morimoto S, et al. (1998) Antihypertensive effect of sesamin. III. Protection against development andmaintenance of hypertension in stroke- prone spontaneously hypertensive rats. Biol Pharm Bull 21: 469-473.
  18. Kita S, Matsumura Y, Morimoto S, Akimoto K, Furuya M, et al. (1995) Antihypertensive effect of sesamin. II. Protection against two-kidney, one-clip renal hypertension and cardiovascular hypertrophy. Biol Pharm Bull 18: 1283-1285.
  19. Hemalatha S, Ghafoorunissa (2004) Lignans and tocopherols in Indian sesame cultivars. J Am Oil Chem Soc 81: 467-470.
  20. https://www. researchgate. net/figure/Expelling-process-flow-chart_fig1_290759771
  21. Yamada Y, Obayashi M, Ishikawa T, Kiso Y, Ono Y, et al. (2008) Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice. J Nutr Sci Vitaminol (Tokyo) 54: 117-123.
  22. Collinge W, American Holistic Health Association (1996) The American Holistic Health Association Complete Guide to Alternative Medicine. Warner Books, New York, USA. 24) Costa FT, Neto SM, Bloch C Jr, Franco OL (2007) Susceptibility of human pathogenic bacteria to antimicrobial peptides from sesame kernels. Curr Microbiol 55: 162-166.
  23. Chavali SR, Zhong WW, Forse RA (1998) Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice. Prostaglandins Leukot Essent Fatty Acids 58: 185-191.
  24. Chavali SR, Zhong WW, Utsunomiya T, Forse RA (1997) Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. Int Arch Allergy Immunol 114: 153-160.
  25. Balan V, Rogers CA, Chundawat SPS, da Costa Sousa L, Slininger PJ, et al. (2009) Conversion of Extracted Oil Cake Fibers into Bioethanol Including DDGS, Canola, Sunflower, Sesame, Soy, and Peanut for Integrated Biodiesel Processing. J Am Oil Chem Soc 86: 157-165.
  26. http://faostat. fao. org/site/339/default. aspx
  27. Moazzami AA, Kamal-Eldin A (2006) Sesame seed is a rich source of dietary lignans. J Am Oil Chem Soc 83: 719-723.
  28. El Tinay AH, Khattab AH, Khidir MO (1976) Protein and oil compositions of sesame seed. J Am Oil Chem Soc 53: 648-653.
  29. Supercritical Fluids (SCF) and supercritical Fluid Extraction (SFE) prepared at thermodynamics research laboratory, Department of Chemical Engineering.

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Pawar Nikita Nitin
Corresponding author

Navsahydri institute of pharmacy

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Shendkar Akanksha Bharat
Co-author

Navsahydri institute of pharmacy

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Kore Arundhati Narayan
Co-author

Navsahydri institute of pharmacy

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Shelar Jagruti Jagannath
Co-author

Navsahydri institute of pharmacy

Nikita Pawar, Akanksha Shendkar, Arundhati Kore, Jagruti Shelar, A Review on Sesame (Sesamum indicum L.), Int. J. of Pharm. Sci., 2025, Vol 3, Issue 6, 536-542. https://doi.org/10.5281/zenodo.15589800

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