Department Of Pharmaceutics, LBYP College Of Pharmacy, Pathri, Aurangabad, Maharashtra, India
A new strategy that combines inventive development, formulation, new technology, and novel methodology for delivering pharmaceutical compounds in the body as needed to successfully achieve their targeted pharmacological effect is known as a novel drug delivery system. There are numerous novel drug delivery systems available. Among them, "drug- loaded erythrocytes" are one of the most expanding and prospective systems for the delivery of medications and enzymes. Erythrocytes are natural components that make them suitable for use as drug delivery systems to enhance the pharmacokinetics, bioavailability, and many other properties of several medications. Erythrocytes are highly beneficial for targeted and controlled drug delivery systems. Erythrocytes are biocompatible, biodegradable, have a long circulation half-life, and can be loaded with a range of biologically active substances. The aim of the present review is to focus on various features, composition, advantages, disadvantages, isolation, drug loading methods, storage, route of administration, evaluation, application, and novel approaches, future perspectives to resealed erythrocytes.
Pallavi Ambadas Dandge*, Ms. Pranali Hatwar, Gajanan Sanap, Review On Resealed Erythrocytes As A Novel Drug Delivery System, Int. J. in Pharm. Sci., 2023, Vol 1, Issue 12, 108-120. https://doi.org/10.5281/zenodo.10259634