Department of Pharmacy Practice, Periyar College of Pharmaceutical Sciences, Tiruchirappalli.
Context: Patient counseling is defined as providing medication information in verbal or non-verbal form to patients or their representatives on direction of use, advice on side effects, precautions, storage, diet and life style modification. Aim: The main aim of this study is to assess the impact of pharmacists provided patient counseling on treatment outcomes and quality of life in depressive patients, improving their knowledge. Methods and Materials: Effective care involves counseling on disease management, lifestyle modification and regarding the medication. Numerous studies have shown that counseling and psychotherapy are effective treatments for depression. A meta-analysis of various psychotherapy studies found that therapy significantly reduces depressive symptoms compared to no treatment or placebo. Moreover, the combination of counseling with medication is often more effective than either treatment alone. Result :The impact of patient counseling in the treatment of depression is multifaceted and can lead to substantial improvements in various aspects of a patient’s life. Pharmacists-led interventions, including medication adherence support, education and collaborative care, have shown to improve depression management outcomes. Conclusion :Patient counseling has a profound and positive impact on the management of depression. It not only helps alleviates symptoms but also contributes to long-term recovery and well-being, making it an essential component of comprehensive mental health care.
Patient counselling is defined as providing medication information orally or in written form to the patients or their representatives on direction of use, advice on side effects, precautions, storage, diet and life style modifications.
Objective of patient counselling:
Patient counselling consist of three stages:
Issues regarding Manner:
Patient counselling for depression :
Depression, or major depressive disorder, is a prevalent and severe medical condition that adversely affects how you feel, think, and act. It often manifests as persistent feelings of sadness and a marked loss of interest in activities you once enjoyed. This condition can lead to a range of emotional and physical issues, significantly impairing your ability to perform at work and home. Depression is characterized by various symptoms, which can fluctuate in intensity. One of the challenges in dealing with depression is that the very nature of the disorder can delay the decision to seek help. However, it is important to note that depression is treatable, and with the right interventions, individuals can manage their symptoms and improve their quality of life.[2]
Types of Depression:
Symptoms of Depression:
Depression can occur multiple times throughout life, with episodes characterized by symptoms experienced most of the day, nearly every day. These symptoms may include:
Depression Symptoms By Age Group:
Children: Although depression is rare in children under 12, it can still occur. Symptoms include sadness, school difficulties, loss of interest in activities, changes in eating habits, anxiety, and avoiding social interactions. Causes may include family stress, abuse, or the loss of a pet or loved one. Early therapy can be helpful, and parents should seek referrals from a paediatrician or school counselor if needed.
Teens: While mood swings are common in teens, persistent changes in mood, irritability, feelings of worthlessness, or self-harm behaviours may signal depression. Factors such as peer pressure, hormonal changes, sleep issues, and social rejection can contribute. Parents should approach the topic gently and seek medical advice to rule out physical causes and possibly consult a mental health professional.
Young Adults( 19-29): Depression in individuals aged 19 to 29 can stem from major life transitions, relationship problems, or a lack of support. Encouraging them to build a support network and seek therapy is important. They should also be encouraged to discuss symptoms with a healthcare provider.
Midlife Adults (30-69): People aged 30 to 60 may experience depression due to stressors like caring for children and aging parents, financial issues, or health concerns. Symptoms might include substance abuse, anger, or risky behaviour. It's important to encourage them to talk about their concerns, practice self-care, and consult a doctor for evaluation and treatment.
Senior Adults(70+): Depression in older adults is common but often goes unnoticed. Symptoms include sleep problems, fatigue, persistent sadness, and mood changes. Factors like social isolation, loss of a spouse, and health issues can contribute. Encouraging social engagement and a discussion with a doctor can help, as treatment can improve their well-being.[5]
Causes Of Depression:
Several factors are believed to contribute to the development of depression:
Need For Patient Counselling:
Patient counselling for depression is crucial as it significantly enhances treatment effectiveness, improves symptom management, and empowers individuals. The integration of counselling with medication can lead to better outcomes and increased compliance with treatment. Notably, cognitive-behavioural therapy (CBT) effectively reduces depressive symptoms and prevents relapses. Counselling also fosters emotional resilience and equips patients with coping strategies, enabling them to recognize early warning signs of depression and implement effective strategies promptly. Counselling emphasizes the importance of a collaborative and supportive therapeutic alliance between the patient and the counsellor. This relationship is foundational to achieving success in therapy, as a trusting environment allows individuals to express their thoughts and feelings freely. The process not only draws on the expertise of mental health professionals but also actively involves patients, facilitating their personal growth and self-awareness. Moreover, it helps improve overall quality of life by addressing personal issues and enhancing support systems. ?Overall, patient counselling plays a vital role in managing depression and supports individuals towards long-term recovery.[7]
Strategies To Improve Patient Counselling:
Consider a broad psychiatric diagnosis when assessing a patient with depressed or anxious mood, as misdiagnosis is frequent and negatively affects outcomes. Make specific and appropriate referrals to specific form psychotherapy, such asInter personal therapy(IPT),cognitive-behaviour therapy (CBT) andproblem solving therapy(PST). Providing key educational messages at the beginning of treatment can enhance treatment adherence, particularly with regard to antidepressant medication use. Early monitoring for adherence, treatment response and side effects can improve adherence and outcomes. Treat depression until remission in order to decrease relapse rate. Change treatment after 6 weeks, if there is no or very minimal response to initial medication. Evaluate every anxious or depressed patient for alcohol or drug abuse.[8]
Make specific and appropriate referrals for psychotherapy:
Just as there are specific medications, there are specific forms of psychotherapy. Patients with anxiety disorders in particular, benefit from cognitive behavioural therapy (CBT), in which they undergo exposure to their fears and gain mastery over them. There are several forms of effective psychotherapy for depression, including CBT and interpersonal therapy. Non-specific ‘supportive’ therapy can help people in times of crisis or stress but is typically not efficacious for serious mental health disorders. Family therapy or behavioural marital therapy can be effective when dysfunction in families or couples is a primary driver of the patient's depressive symptoms. Providers should be aware of local therapists who practice evidence-based forms of treatment.
Counselling Strategies
Education and negotiation
When managing depression, it's crucial to educate patients about the nature of their condition. They should be informed that depression is a common illness, producing genuine symptoms, and that these symptoms are not due to personal failure or "craziness." It’s helpful to explain that depression often stems from a biological predisposition, which can be triggered by life stress. With appropriate treatment, depression typically improves, though patients should be aware that relapse can occur if treatment is stopped, necessitating long-term management or follow-up. After providing this information, it’s important to gauge the patient's willingness to accept a diagnosis of depression. If there is any resistance, healthcare providers should explore the patient's concerns or other potential health conditions they might be worried about. Some patients might not readily accept a depression diagnosis without ruling out other medical issues. Once the diagnosis is accepted, the patient should be informed about the various treatment options available. They should be involved in deciding on the treatment plan and the goals they hope to achieve. This collaborative approach helps in clearly defining the treatment process, which can otherwise be vague and frustrating. Engaging patients in their care can improve disease management, functional health, and the relationship between patient and physician. Research shows that when psychiatrists work with patients to identify specific treatment goals, it leads to better symptom management, higher compliance with follow-up visits, and greater patient satisfaction.
Increasing pleasurable activities
Encouraging patients with depression to participate in enjoyable and rewarding activities is a crucial part of treatment. These activities can help reduce symptoms by providing a break from negative feelings and giving patients something positive to anticipate. Engaging in pleasurable activities can also help shift their perspective to view themselves and their lives more positively. To identify activities that might be beneficial, physicians can ask questions like, "Have you recently experienced anything that made you feel even a little better?" Based on the patient's responses, doctors can then collaborate with them to increase their involvement in these positive experiences. Recommendations might include pursuing hobbies, spending more time with family and friends, or taking a vacation. These simple steps can complement other treatments and support overall well-being.
Supportive listening
Supportive listening involves empathically hearing patients describe their issues and concerns, which can be beneficial in itself. When physicians use phrases like "I understand why you might feel that way" or "You seem to be managing as well as can be expected," they provide validation and reassurance. These supportive comments can help counteract negative self-thoughts and improve the patient's self-esteem by demonstrating genuine concern. Furthermore, through attentive listening, physicians can evaluate several key aspects: how much of the stressful situation can be addressed, the significance of the patient's thoughts and feelings about it, and the accuracy of those thoughts and feelings. This approach not only supports the patient emotionally but also aids in developing a deeper understanding of their situation.
Problem solving
Helping patients solve problems can reduce their distress and enhance their feelings of control and effectiveness. For individuals with depression, successfully resolving even small issues can improve their sense of competence and hope. This, in turn, may make them more willing to address other challenges and contribute positively to their overall well-being.
Adjusting Expectation
When patients face issues that can’t be altered, physicians can guide them in adjusting their expectations. This might involve helping patients recognize that perfection is unattainable or that things could be worse. The gap between what patients expect and what they actually experience often causes distress. By helping patients align their expectations with reality, physicians can reduce their emotional discomfort.
Modifying Negative thoughts
Addressing negative thoughts is vital for managing depression. Patients often have distorted beliefs about themselves or their situations that can increase distress. Using a log to track moods, triggers, and thoughts helps patients see that negative thoughts, rather than events, influence their feelings.
Counseling can then focus on identifying and challenging these distorted thoughts. Patients can be encouraged to:
1. Examine the events leading to their thoughts.
2. Evaluate evidence supporting or contradicting their beliefs.
3. Consider more realistic alternatives.
4. Identify information that might help alter their thoughts.
If needed, practical methods such as seeking others' opinions, testing feared outcomes, or weighing the pros and cons of negative thoughts can help patients adopt more balanced perspectives.
Recommending self-help materials
Self-help materials can complement the guidance given during medical visits by offering additional education and counseling. They provide broader information than what can be covered in an office visit, allowing physicians to concentrate on the patient’s specific needs. Studies show that self-help books, particularly those with cognitive and behavioural approaches, can significantly reduce depressive symptoms in older adults for up to two years when used as a primary treatment for mild to moderate depression.[9]
Essential Components Of Depression Counselling
Psychotherapy
Psychotherapy, often referred to as talk therapy or counseling, helps people with depression by introducing new thought patterns and behaviours and addressing habits that contribute to the condition. This therapy is provided by a licensed mental health professional and can take place in individual or group sessions. Therapy can be successfully delivered both in-person and through telehealth, with additional support from digital tools like apps. Effective treatments for depression include cognitive behavioural therapy (CBT) and interpersonal therapy. Other approaches, such as brief psychodynamic therapy, may also be beneficial for some individuals.
Cognitive behavioural therapy (CBT)
Cognitive Behavioural Therapy (CBT) is a structured psychotherapy designed to address mental health issues by focusing on changing negative thought patterns and behaviours. Key principles include:
1. Identifying Negative Thoughts:Recognizing and challenging unhelpful thoughts that contribute to psychological problems.
2. Behavioural Changes: Addressing harmful behaviours and learning healthier alternatives.
3. Modifying Core Beliefs: Altering fundamental beliefs about oneself and the world to improve mental health.
4. Developing Coping Skills: Teaching effective strategies to manage symptoms and enhance emotional well-being.
CBT typically involves a set number of sessions where individuals explore their thoughts and emotions, and work to adopt more positive patterns. It can be used alone or with other treatments, tailored to individual needs.[10]
Interpersonal therapy (IPT)
IPT focuses on interpersonal and life events that impact mood and vice versa. IPT aims to help people improve their communication skills within relationships, form social support networks, and develop realistic expectations to better deal with crises or other issues that may be contributing to or worsening their depression.[11]
Problem solving Therapy (PST)
Problem-solving therapy (PST) is a psychotherapy approach that focuses on developing coping skills to handle challenging life situations. Unlike psychodynamic therapy, which examines both current issues and their deeper origins, PST targets immediate problems directly.
Also known as:
- Short-term therapy
- Problem-solving treatment
- Structured problem solving
If your depression is related to everyday problems, your doctor may recommend PST to help you create strategies to address these issues, potentially reducing your depression symptoms.[12]
Family and Couple therapy
Family and couples therapy involves attending sessions with your partner or family members to address issues that may be contributing to your depression. This approach allows you to work together to improve communication, resolve conflicts, and support one another in managing the challenges that affect your mental health.
Psychodynamic physiotherapy:
Psychodynamic psychotherapy involves exploring past experiences, such as childhood events, to understand how they may be influencing your current behaviour. By gaining insight into these underlying factors, you can work to reduce their impact on your present life.[11]
Complementary medicine: This includes treatments used alongside traditional Western medicine. Therapies like acupuncture, massage, hypnosis, and biofeedback can enhance well-being, especially for those with mild depression or persistent symptoms.
Brain stimulation therapy: This approach is beneficial for individuals with severe depression or depression accompanied by psychosis. It includes treatments such as electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), and vagus nerve stimulation (VNS).[13]
Psychotherapy compared with anti-depressants:
When considering antidepressant medication as part of your treatment plan, it's essential to be well-informed about the different types of antidepressants, their potential benefits, and possible complications.
Types of Antidepressants:
Here's a concise overview of antidepressant categories:
S.No |
Class |
Drugs |
Initial dose(mg/day) |
Usual dose ranges (mg/day) |
Adverse effects |
|
1 |
SSRIs (Selective Serotonin Reuptake Inhibitors |
Sertraline |
50 |
100-200 |
Sexual dysfunction Headache QTc prolongation (abnormal heart rhythms and sudden cardiac arrest)
|
|
Fluvoxamine |
50 |
50-200 |
||||
Fluoxetine |
20 |
20-60 |
||||
Paroxetine |
20 |
20-40 |
||||
Citalopram |
20 |
20-40 |
||||
Escitalopram |
5-10 |
10-20 |
||||
2 |
SNRIs (Serotonin/ Norepinephrine Reuptake Inhibitors) |
Venlafaxine |
75 |
225-375 |
Hypertension Headache Diaphoreisis(excessive sweating) Bone resorption
|
|
Desvenlafaxine |
25-50 |
50 |
||||
Duloxetine |
30 |
60 |
||||
Milnacipran |
12.5 |
100 |
||||
Levomilnacipran |
20 |
40-120 |
||||
Desvenlafaxine |
25-50 |
50 |
||||
3 |
TCAs (Tricyclic Antidepressants):
|
Amitriptyline |
50 |
100-200 |
Dry mouth Urinaryretention Constipation QRS prolongation Seizures Orthostatic hypotension
|
|
Clomipramine |
25 |
100-250 |
||||
Doxepin |
50-70 |
75-150 |
||||
Imipramine |
75 |
150 |
||||
Trimipramine |
50-70 |
100-200 |
||||
Desipramine |
100 |
300 |
||||
Nortriptyline |
25 |
50-150 |
||||
Protriptyline |
15-30 |
30-60 |
||||
Maprotiline |
25-75 |
150 |
||||
Amoxapine |
100 |
300 |
||||
4 |
Atypical Antidepressants |
Bupropion |
150 |
300 |
Seizures Sedation and weight gain Hepatotoxicity |
|
Mirtazapine |
15 |
15-45 |
||||
Agomelatine |
25 |
50 |
||||
5 |
Serotonin Modulators |
Nefazodone |
200 |
200-600 |
Hepatotoxicity Sedation and priapism Diarrhoea Nausea
|
|
Trazodone |
150 |
200-400 |
||||
Vilazodone |
10 |
20-40 |
||||
Vortioxetine |
10 |
20 |
||||
6 |
MAOIs (Monoamine Oxidase Inhibitors) |
Selegiline(transdermal patch) |
6 |
6-12 |
Sexual dysfunction Potential for serotonin syndrome
|
|
Moclobemide |
300 |
600 |
||||
Tranylcypromine |
30 |
60 |
||||
Isocarboxazid |
20 |
20-60 |
||||
Phenelzine |
45 |
60-90 |
||||
7 |
NMDA Antagonists (N-methyl-D-aspartate) |
Esketamine(nasal spray) |
56 |
56-84 |
Dissociative or perceptual changes and sedation Dizziness, Headache,Somnolence and dry mouth[15] |
|
Counselling Regarding Lifestyle Modification
Exercise and other supplements:
Exercise is a powerful tool for improving mental health, particularly for individuals experiencing depression or anxiety.
Exercise benefits mental health by:
A nutritious diet supports mental health by:
Sleep:
Sleep issues are a common problem for individuals with depression, often manifesting as difficulty falling asleep, staying asleep, or waking up in the middle of the night with persistent thoughts. This lack of restful sleep can further exacerbate depressive symptoms and lead to increased fatigue, making quality sleep a key component of depression treatment.
To improve sleep, consider these approaches:
Create a Relaxing Bedtime Routine: Engage in soothing activities like reading or taking a warm bath before bed to help signal to your body that it’s time to wind down.
Stick to a Regular Sleep Schedule: Go to bed and wake up at the same time each day, even on weekends, to help regulate your internal clock.
Optimize Your Sleep Environment: Ensure your bedroom is dark, quiet, and cool to create a more conducive atmosphere for restful sleep.
Implementing these strategies can help enhance the quality and duration of sleep, which is crucial for managing depression and improving overall well-being.
Relationship:
Depression can lead to feelings of isolation, making supportive relationships even more crucial. Surrounding yourself with positive, caring friends and loved ones can provide essential emotional support and help you navigate difficult times.
Stress Management:
Chronic stress can exacerbate depression and negatively impact your well-being. Managing stress effectively is vital for maintaining mental health. Since stress management techniques can vary greatly from person to person, it's important to find what works best for you. Some effective strategies might include:
Impact Of Patient Counseling:
Numerous studies have shown that counseling and psychotherapy are effective treatments for depression. A meta-analysis of various psychotherapy studies found that therapy significantly reduces depressive symptoms compared to no treatment or placebo. Moreover, the combination of counseling with medication is often more effective than either treatment alone. The impact of patient counseling in the treatment of depression is multifaceted and can lead to substantial improvements in various aspects of a patient’s life. Pharmacists-led interventions, including medication adherence support, education and collaborative care, have shown to improve depression management outcomes. Patient counseling plays a crucial role in addressing the debilitating effects of depression, providing a supportive framework to help individuals navigate the overwhelming emotions and thoughts that accompany the condition. When depression descends like a dark cloud, it can distort the way you think, feel, and behave, making everyday life a struggle. However, patient counseling offers a pathway to understanding and managing these challenges. Through counseling, individuals can gain insight into how depression impacts their personal and professional lives, often by disrupting their sense of self, motivation, and relationships. A skilled counselor can help unravel these invasive impacts, guiding patients to develop healthier coping mechanisms and rebuild their sense of purpose and joy. Counseling sessions often focus on identifying negative thought patterns, addressing emotional numbness, and finding strategies to manage overwhelming stress. By engaging in patient counseling, those experiencing depression can learn to regain control over their lives, counteract the heavy, bleak feelings, and work towards restoring meaning and fulfilment, even when the root cause of their depression isn't immediately clear. The consistent support and guidance provided through counseling can significantly alleviate symptoms, making it a vital component in the overall treatment and management of depression.[17]
CONCLUSION:
Evidence indicates that pharmacist-provided counseling and interventions significantly improve the management of depression by enhancing medication adherence, clinical outcomes, patient satisfaction, and reducing healthcare costs while supporting self-management. Depression, a major depressive disorder, requires a blend of pharmacological and non-pharmacological treatments for effective control. Adherence to medication and lifestyle modifications is crucial in managing depression. Pharmacists, as vital members of the healthcare system, have a key role in counseling patients, necessitating continuous updates on the latest developments and strong verbal and non-verbal communication skills. They help patients better understand their illness and the role of medication, establish ongoing working relationships for continuous support, and improve patients' comprehension of managing medication side effects and drug interactions. Pharmacists ensure better compliance with medication regimens, reduce medication errors, and lower unnecessary healthcare costs. They should be seen as professionals who provide comprehensive pharmaceutical care, prevent drug interactions and adverse reactions, and build relationships with patients, healthcare providers, and other stakeholders. Additionally, pharmacists offer opportunities for addressing final concerns, assist in planning and follow-up, and verify patient understanding through feedback, ensuring effective and supportive care.
REFERENCES
G. Sindhuja, S. Siva Ranjani, A. Seran selciya, A. Shanmugapriya, C. Rajesh*, R. Senthamarai, Impact Of Patient Counselling for Depression, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 12, 385-396. https://doi.org/10.5281/zenodo.14272303