1Assistant professor,Department of pharmaceutics,Rajiv Gandhi institute of pharmaceutical science and research,Trikaripur,Kasaragod,Kerala
2
Toothpaste is a gel or paste formulation product and is used to clean and maintain oral hygiene with the aid of toothbrush. The majority of the cleaning is performed by the mechanical utilisation of the toothbrush with the help of excipients used in toothpaste. The aim of this investigation is to evaluate herbal toothpaste formulation. Herbal toothpaste with natural ingredients is more acceptable in public opinion than chemical-based formulation due to their safety and efficacy in reducing dental caries and preventing other dental disorders. The objective of the present research work is to formulate herbal toothpaste containing natural ingredients like Neem, Clove, Black-seed oil and walnut. These extracts have anti-bacterial, anti-caries, anti-ulcer, anti-oxidant and anti-fungal activities.The physicochemical evaluation of selected plants were within the pharmacopoeial limit and phytochemical screening in ethanol and water extracts showed the intensive presence of constituents like Alkaloid, Flavonoids, Glycosides, Phenols and tannins. The formulated herbal toothpaste were evaluated to determine important physical characteristics such as pH, Foamability, Spreadability, Abrasiveness, Extrudability and Shape retention in order to develop a more effective and stable product. All in-vitro evaluations of prepared herbal toothpaste showed better result. The developed formulation showed anti-bacterial activity against bacterial culture and produced a better zone of inhibition.The purpose of this project is to make and test the prepared herbal toothpaste. This research proves that our herbal based toothpaste formulation with natural ingredients is excellent as it gets in terms of performance.
Sharanya R. K. , Fathimath Fitha M. A. , Anisa A. , Muhammed Sahadath K. , Sameena P. L. , Thanveera Kunheeritheeri , Formulation And Evaluation Of Polyherbal Toothpaste, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 9, 1333-1340. https://doi.org/Sharanya R. K. , Fathimath Fitha M. A. , Anisa A. , Muhammed Sahadath K. , Sameena P. L. , Thanveera Kunheeritheeri , Formulation And Evaluation Of Polyherbal Toothpaste, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 9, 1333-1340. https://doi.org/10.5281/zenodo.13850938