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Abstract

Solubility is the process of dissolution of a solute in solvent, which is essential to formulate number of dosage forms. Bioavailability of drugs can be improved by increasing the solubility of drugs. To design oral formulations using drug candidates with poor solubility is a big challenge in pharmaceuticals. Solubility of drugs can be enhanced by different techniques by modifying their chemical properties, physical characteristics and by converting the drugs into their salt forms. Few methods to increase solubility of poorly soluble drugs is reviewed in this study.

Keywords

Solubility, enhancement, co-solvency, solid dispersion

Reference

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Arpitha G.
Corresponding author

Shridevi Institute of Pharmaceutical Sciences, Tumkur

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Harshitha T. P.
Co-author

Shridevi Institute of Pharmaceutical Sciences, Tumkur

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Madhu G. R.
Co-author

Shridevi Institute of Pharmaceutical Sciences, Tumkur

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Jamuna K. R.
Co-author

Shridevi Institute of Pharmaceutical Sciences, Tumkur

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Maruthi T. Kovi
Co-author

Shridevi Institute of Pharmaceutical Sciences, Tumkur

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Jeevan S.
Co-author

Shridevi Institute of Pharmaceutical Sciences, Tumkur

Arpitha G. , Harshitha T. P. , Madhu G. R. , Jamuna K. R. ,Maruthi Thippanna Kovi, Jeevan S. , An Overview On Various Techniques To Enhance Solubility Of Poorly Soluble Drugs, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 2, 316-322. https://doi.org/10.5281/zenodo.10653108

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