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  • Formulation And Evaluation Of Face Scrub In Modern Pharmaceutics: An Herbal Formulation
  • 1Director (Academic and Research), Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.
    2Associate Professor, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.
    3Assistant Professor, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.
    4,5Student, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.
     

Abstract

Background: In today’s life for both women and men cosmetics plays an important role to beautifying and altering the appearance of skin. The use of natural ingredients to remain healthy and of good appearance, the skin surface requires frequent cleansing to remove oil, sebum and other secretions, dead cells, crusts and applied make-ups. Aim: This study aims on the formulating an herbal Face Scrub using natural ingredients incorporated into gel, For the purpose of enhancing skin beauty, several skin conditions are developed, such as skin protection, sunscreen, anti-acne, and anti-wrinkle products. Material and Method The aim of study is to formulate and evaluate a face scrub with incorporation of the Tamarind an active ingredient. For the purpose of enhancing skin beauty, several skin conditions are developed, such as skin protection, sunscreen, anti-acne, and anti-wrinkle products. In this preparation, Roasted gram peel are used to exfoliating activity. Other natural ingredients are tamarind powder and multani mitti used to remove grene, dust particles and acne. Esthetic ingredients used in this formulation include neutralizer, moisturizer and surfactants. Among this ingredients, gelling agent and preservative was used. Result: The herbal scrub was prepared and evaluated. The herbal facial scrub formulated in the laboratory was found to be compared with various parameters such as appearance, pH, and spreadability, wash ability, irritability and found to be satisfied with all required characterization. Conclusion The aim of formulating an Herbal face scrub was found to successful with good results. The face scrub showed a good spreadability. The formulation showed a good peel off property on our skin without causing skin irritation or edema

Keywords

Herbal Face Scrub, Tamarind, Honey, Skin, Roasted Gram peel etc

Introduction

Cosmetics Throughout History

The origin and evolution of cosmetics, from ancient times to the modern era.

Ancient Origins of Cosmetics

The term "cosmetics" traces its roots to the Greek word "kosmeticos," meaning adornment. Since ancient tribal days, humans have adorned themselves for beautification, with both men and women using various materials.

Evolution of Cosmetics

Over time, cosmetics expanded beyond adornment to include items like high-heeled shoes and artificial dentures. The acceptance and role of cosmetics in daily life increased significantly post-World War II, as they were recognized for their psychological and skincare benefits.

Modern Understanding of Cosmetics

Cosmetics are now considered essential commodities, not merely for adornment but also for skincare and psychological well-being. The skin, particularly the face, serves as an indicator of an individual's health.

Herbal Cosmetics and Cosmeceuticals

Herbal cosmetics utilize natural ingredients with cosmetic benefits, gaining popularity for their gentle and non-toxic properties. Cosmeceuticals, introduced in the 1990s, combine cosmetic and pharmaceutical properties, often using plant-based active ingredients for therapeutic benefits.

Medicinal Plants and Extraction Techniques

Medicinal plants have been used historically for various ailments and are now recognized as important sources of drugs. Extraction methods, including distillation, maceration, and solvent extraction, are used to obtain active components from plants for medicinal purposes.

Facial Scrubs and Exfoliation

Facial scrubs use mechanical or chemical means to exfoliate the skin, removing dead cells and promoting cell turnover. Herbal facial scrubs offer benefits such as reducing age-related changes and environmental damage.

Benefits of Scrubbing Your Skin

Scrubbing cleanses the skin, removes dead cells, and improves skin texture, promoting a clear, smooth, and glowing complexion. It can also help in the removal of dark patches, acne scars, and prevention of ingrown hair. At the end, Cosmetics have a rich history rooted in human desire for adornment and skincare. From ancient practices to modern formulations, cosmetics continue to play a vital role in personal grooming and well-being.

MATERIAL

Plant Material

Roasted gram Peel Powder, Tamarind Powder, Multani Mitti, Aloe vera, Saffron strand, Neem powder, Turmeric powder, Tulsi powder was taken as plant material in this formulation. Aloe-vera was collected from the Botanical Garden, Lucknow Model College of Pharmacy, Lucknow. Roasted gram Peel Powder, Tamarind Powder, Multani Mitti, Aloe vera, Saffron strand, Neem powder, Turmeric powder, Tulsi powder was purchased from the local market of Dubagga, Lucknow.

  1. Aloe-Vera

Synonym-

Aloe vera, burn plant

Biological source

Dried latex of leaves of it also known as cape aloe belong to the

Family-liliaceae

Description

Colour- clear to slightly yellow / translucent gold Odour-similar like rotten garlic or onion.

Taste- Bitter

Chemical constituents - aloe emodin.

Uses - heals burns and clears acne.



    Image

Fig 1: Aloe-Vera


  1.  Honey

Synonym – Shahad

Biological source

It consists of saccharine liquid prepared from the nectar of the flowers by Honeybee Apis mellifica belonging to family Apadae.

Description

Colour- Yellow brown coloured liquid,

Odour – Sweet, Taste – Sweet.

Chief chemical constituents - Dextrose and laevulose (70-80%) Dextrin (0.06-1.25%) Proteins

Uses - Good for wrinkles and aging Prevent acne Remove dirt from pores.



    Image

Fig 2: Honey


  1. Turmeric Powder

Synonym

Curcuma longa

Biological source

It consists of dried rhizomes of Curcuma longa belonging to family Zingiberaceae.

Description

Colour - Yellow,

Odour – Aromatic,

Taste – Bitter

Chief chemical constituents - Curcumin, Curcuminoids

Uses

Reduce acne, Glowing skin and Lightens skin. Turmeric has the potential to reduce swelling (inflammation) and irritation. Inflammation and irritation can aggravate other skin conditions, so using turmeric as a regular face mask can help.



    Image
  1. Tulsi Leaves Powder

Synonym

Tulsi

Biological source

It consists of dried leaves of Ocimum sanctum L belonging to family Lamiaceae.

Description

Colour- green , Odour-aromatic

Taste - Pungent

Chief Chemical constituents - oleanolic acid, ursolic acid, rosmarinic acid

Uses

Prevents acne and pimples, Improve skin texture, Cleanser



    Image

Fig 4: Tulsi Leaves Powder


  1. Saffron

Biological source:

It is the dried stigma and style tops of Crocus sativus Linn., belonging to family Iridaceae.

Description:

Colour- yellow-orange, Odour-aromatic

Taste: Bitter

Chief Chemical constituents  :

carotenoids (crocetin, crocin, ?-carotene, lycopene and zeaxanthin), monoterpene aldehydes (picrocrocin and safranal), monoterpenoids, and isopherones.

Uses

Protect the skin from harmful UV rays.



    Image

Fig 5: Saffron Stand


  1. Sandelwood Powder

Biological source –

Its oil is obtained by distillation of sandalwood, Santalum album Linn., belonging to family Santalaceae.

Description –

Colour- soft neutral with subtle reddish-brown undertones,

 Odour- rich creamy

Taste- creamy, nutty taste similar to a macadamia, hazelnut, or almond.

Chief Chemical constituents - Sandalwood oil contains more than 90% sesquiterpenic alcohols of which 50–60% is the tricyclic ?-santalol.

Uses - Antiseptic and preservative



    Image

Fig.6: Sandalwood


  1. Tamarind Powder

Synonym

Indian date, sour pulp, savanna date, and tamarindo.

Biological source –

Its oil is obtained by distillation of sandalwood, Santalum album Linn., belonging to family Santalaceae.

Description –

Colour- soft neutral with subtle reddish-brown undertones,

Odour- rich creamy

Taste- creamy, nutty taste similar to a macadamia, hazelnut, or almond.

Chief Chemical constituents –

Sandalwood oil contains more than 90% sesquiterpenic alcohols of which 50–60% is the tricyclic ?-santalol.

Uses –

Antiseptic and preservative



    Image

Fig.7: Tamarind


  1.  Neem

Synonym

Margosa, neem, nimtree or Indian lilac, is a tree

Biological source

Neem consists of the fresh or dried leaves and seed oil of Azadirachta indica

J. Juss (Melia Indica or M. azadirachta Linn.). belonging to family Meliaceae.

Description

Colour- Vibrant green ,

Odour- garlic/sulfur

Taste- Extremely bitter.

Chief Chemical constituents

Oleic acid (50-60%), palmitic acid (13-15%), stearic acid (14-19%), linoleic acid (8-16%) and arachidic acid (1-3%).

Uses

Neem has antiseptic qualities that can benefit the face.



    Image

Fig 8: Neem


  1. Rose

Description –

Colour- shade of red.

Chief Chemical constituents –

Flavonoids, triterpenes, tannins, phenolic acids, polysaccharides, fatty acids, organic acids, carotenoids and vitamins.

Uses –

It help regenerate skin tissues and delay the signs of aging. The antioxidants neutralize free radicals that quicken the appearance of wrinkles, fine lines, and freckles.



    Image

Fig.9: Rose petal


  1. Multani Mitti

Synonym-

Multan clay

Biological source

It consists of hydrous aluminum silicates (clay minerals)

Description

Colour- White Odour - Pleasant

Taste – Pleasant

Chief chemical constituents

Montmorillonite, Kaolinite, Attapulgite

Uses-

Nourishes skin, reduce oiliness, Remove blackheads.



    Image

Fig.10: Multani mitti.


Chemicals

Carbopol 940, Methyl paraben, Triethanolamine, Propylene Glycol, Rose Water and Sodium Lauryl Sulphate was collected from the chemical store room of Lucknow Model College of Pharmacy, Lucknow.

METHOD

Preparation of gel-

Methyl paraben was weighed and dissolved in a beaker containing water. Carbapol 940 was added and stirred constantly for few minutes it forms a gel. Sodium Lauryl Sulphate was weighed dissolved separately with water and was added into the above gel. Then the propylene glycol was added. The, tamarind powder, sandalwood powder and the multani mitti was triturated well into the mortar and pestle. Then the prepared gel was added into the active ingredient mixture and stirred. At the end, triethanolamine was added to adjust the pH.

Preparation of exfoliant-

The tamarind peel powder was used as exfoliant. The tamarind peel was taken into the mortar and triturate by using pestle.

PREPARATION OF PLANT MATERIAL EXTRACT

Preparation of Tulsi extraction-

  • Firstly, we collected Tulsi from local market.
  • Then dried them in Sun light.
  • After that, dissolve in a water.
  • Then cover it well with aluminum foil and keep it for 3 to 4 days
  • After that it will be heated in a water bath at 80 degree until the extract comes out .
  • At last filter extract with the help of filter paper.


    Image

Fig 11: Extraction Process of Tulsi


Preparation of turmeric powder extraction-

  • Firstly, we collected turmeric from local market.
  • Then dried them in Sun light.
  • After that, dissolve in a water.
  • Then cover it well with aluminum foil and keep it for 3 to 4 days
  • After that it will be heated in a water bath at 80 degree until the extract comes out .
  • At last filter extract with the help of filter paper.


    Image

Fig 12: Extraction Process of Turmeric Powder 


Preparation of turmeric powder extraction-

  • Firstly, we collected turmeric from local market.
  • Then dried them in Sun light.
  • After that, dissolve in a water.
  • Then cover it well with aluminum foil and keep it for 3 to 4 days
  • After that it will be heated in a water bath at 80 degree until the extract comes out .
  • At last filter extract with the help of filter paper.


    Image

Fig,13: Preparation of sandal-wood powder extraction


FORMULATION OF HERBAL FACE SCRUB

Formulation of herbal face scrub is as follows.


Table 1: Formulation of Herbal Face Scrub


    Image


Procedure

  • Firstly, weighed all the ingredients properlye
  • Then methyl paraben weight and dissolve in a beaker containing water.
  • carbapol was added and stirred continuously until it form a gel.
  • sodioum loryl sulphate weight.dissolve saprately with water
  • Then added into a gel followed by propylene glycol.
  • Then mix a all ingredient in a gel.
  • Then, take a pestle mortar and firstlypour Multani mitti.powder in it.
  • After that add turmerind powder, sandalwood powder triturate it.
  • Add a gel into a pestle motar.
  • At last, grind mix all the ingredients properly.
  • Then the product was prepared and transfer to the air tight container.

EVALUATION PARAMETERS

  1. Appearance.

The prepared scrub was evaluated for its odour and colour. The colour was found to be brown in colour and odour was found to be characteristics.

  1. Consistency.

It was found to be semisolid and homogeneity with visual observation.

  1. pH

pH of the prepared scrub was evaluated. Small amount of the gel was applied on the pH paper and found tobe 7. It is a neutral in nature.

  1. Spreadability.

The spreadability is very important in the behavior of gel that comes out from the tube. It is used to identify the extend of spreadability by the gel on the skin. A small quantity of sample was placed on a glass slide and another slide was placed above them; 100 g of weight was placed on the slide. The time taken for the gel to spread on the slide was noted and measured which was found to be 4 cm in 60 sec. It was calculated by using following formula:

S=m×????/????

S= Spreadability

m=Weight placed on slide

l=Length of the glass slide

t= Time taken in seconds

  1. Extrudability.

Small amount of gel was taken into a collapsible ointment tube. One end close and the other end keep opened. Slight pressure was applied on the enclosed side. The time taken to extrude and theamount of the gel extruded was noted.

  1. Irritability.

A small amount of the gel was applied on the skin and kept for few minutes and found to be non- irritated.

  1. Washability

A little quantity of gel was applied over the skin and was wash with water and it was easily washable.

  1. Grittiness

Gel was found to have a few gritty particles

RESULT

The herbal scrub was prepared and evaluated. The herbal facial scrub formulated in the laboratory was found to be compared with various parameters such as appearance, pH, and spreadability, wash ability, irritability and found to be satisfied with all required characterization. Thus, the developed formulation can be used as an effective scrub for using it to bear a healthy and glowing skin. It contained Roasted gram peel powder, tamarind, tamarind powder, and multani mitti which has exfoliation activity, lighten skin tone and reduce dark spots and cleaning of oil and dust particles respectively. The Roasted gram peel powder was a natural exfoliating agent which was used to remove dead cells of skin, gives scrubbing property to the skin and which helps to improve the blood circulation. Tamarind powder helps to remove oil, sebum and other secretions of skin to lighten skin tone. The multani mitti was associated with removing dust particles and grene. After using the scrub, skin was sure to feel softer, cleaner and refreshed. It made skin beautiful, youthful and soft and glowing. Herbal cosmetics showed lesser or no side effects, hence use of herbal cosmetics get increased.



    Image

Table 2: Result of evaluation parameter of Herbal Aloe-Vera Skin Gel


CONCLUSION

The aim of formulating a Herbal face scrub was found to successful with good results. The face scrub showed a good spreadability. The formulation showed a good peel off property on our skin without causing skin irritation or edema. The present study was attempted to make an herbal scrub using suitable base to form a gel. The prepared scrub was compared with various parameters like colour, odour, consistency, pH, spread ability, extrudability, irritability, wash ability, grittiness, foamability and found to be satisfied with all required characterization. Thus, the developed formulation can be used as an effective scrub for using it to bear a healthy and glowing skin. In this all-natural ingredient were used, so that they had no side effects or fewer side effects. The prepared herbal scrub was found to be satisfied for the application on the skin to make it healthy and glowing. The application of the scrub gel which helps to improve blood circulation and increases oxygensupply to all surface of the skin. After application of scrub, skin becomes softer, cleaner and refreshed.

CONFLICT OF INTEREST:

None

FUNDING:

This project is supported by Lucknow Model College of Pharmacy, Lucknow.

ACKNOWLEDGEMENT:

The author would like to thank Dr. Amit Singh (Vice- Chairmen, Lucknow Model group of colleges) and all their mentors. The notes compiled here are collected over a period of time and may have been reproduced verbatim. Apologize to all researchers if in-advertently failed to acknowledge them in the references.

REFERENCES

  1. Fatima Grace X, Anbarasan B, Kanimozhi T, Shanmuganathan S*. Preparation andEvaluation of Deep Cleansing Exfoliator. Asian J Pharm Clin Res 2018; Vol. 11, Issue 7.
  2. Aglawe SB*, Gayke AU, Khurde A, Mehta D, Mohare T, Pangavane A, Kandalkar
  3. S. Preparation and Evaluation of Polyherbal Facial Scrub. J Drug Delivery and Therapeutics.2019; 9[2]:61-63
  4. Charulata T. Nemade*, Nayana Baste. Formulation and Evaluation of a Herbal Facial Scrub. World J Pharm Res 2014; Vol. 3, Issue 3, 4367-4371.
  5. Mahajan S, Gayakwad D, Tiwari A, Darwhekar GN: Formulation and Evaluation of Herbo- Mineral Facial Scrub. Journal of Drug Delivery and Therapeutics 2020 May 15;10(3):195-7
  6. Carvalho Neto DP, Gonot-Schoupinsky XP, GonotSchoupinsky FN: Coffee as a Naturally Beneficial and Sustainable Ingredient in Personal Care Products: A Systematic Scoping Review of the Evidence.
  7. Farheen B, Mohammed I: Design and development of unani face pack for skin care. European J Pharm Med Red. 2016;3(2):627- 632.
  8. Ghode DS, Chatur VM, Ghode DP, Shaha N, Prajapati S, Thorave A: Formulation And Evaluation Of Facial Scrub Containing Sunflower Seeds And Other Natural Ingredients. - Research. 2019 Jun 20;8(9):1772-81.
  9. Himaja N. Ashok kumar A, Bhart kumar B: Preparation and Evaluation of Poly Herbal Fruit Face Mask. J Res Pharm Sci. 2015;2(11):07-13.
  10. Upadhyay G, Verma S, Parvez N, Sharma PK: Recent trends in transdermal drug delivery system-a review. Advances in biological research. 2014;3:131-380.
  11. Yamini. K and Onesimus. T. Preparation and Evaluation of Herbal Anti-Acne Gel. Int J Pharm Bio Sci 4.2 (2013): 956 – 960.
  12. Gupta Anil, Sharma P.C, Tilakratne B M K S and Verma Anil K. Studies on physiochemical characteristics and fatty acid composition of wild apricot (Prunus armeniaca Linn.) kernel oil. Indian Journal natural Products and Resources 3.3 (2012): 366-370
  13. Jody P. Ebanks, R. Randall Wickett and Raymond E. Boissy. Mechanisms Regulating Skin Pigmentation: The Rise and Fall of Complexion Coloration. International Journal of Molecular Sciences 10 (2009): 4066-4087.
  14. Aswal A, Kalra M, Rout A. Preparation and evaluation of polyherbal cosmetic cream.Asian Pac J Trop Med 2012; 5:83-88, 1-4
  15. Pandey Shivanand, Meshya Nilam, D.Viral, Herbs Play an Important Role in the Field of Cosmetics, International Journal of PharmTech Research, .2(1); 632-639:2010.
  16. Prashant L Kole, Hemant R Jadhav, Prasad Thakurdesai and Anantha Naik Nagappa, cosmeticspotential of herbal extracts, Indian Journal of Natural Products and Resources (IJNPR) [FormerlyNatural Product Radiance (NPR)], 4(4); 315-321, 2005.
  17. Rutuja Prashant nangare, trupti Ashok thange. Formulation and evalution of polyherbal facial scrub page no.1, International Journal of Research Publication and Reviews.
  18. J. Prathyusha, N. S. Yamani, G. Santhosh, A. Aravind, B. Naresh Formulation and Evaluation of Polyherbal Face Scrubber for Oily Skin in Gel Form International Journal of Pharmaceutical Sciences and Drug Research 2019; 11(4): 126-128.
  19. Larsson, S.C.; Bergkvist, L.; Näslund, I.; Rutegård, J.; Wolk, A. Vitamin A, retinol, and carotenoids and the risk of gastric cancer: a prospective cohort study. Am. J. Clin. Nutr., 85(2); 497–503, 2007.
  20. Plants Database.United States Department of Agriculture [online].Natural Resources Conservation Service. Available at:http://plants.usda.gov/java/namesearch.Accessed, 2006.
  21. Drugs act Commercial?s, “Manual on Drugs and Cosmetics” [online], Second Edition,Published by Commercial Law Publishers (India) Pvt. Ltd., 2004.
  22. Grace Fatima et al. Preparation and Evaluation of Deep Cleansing Exfoliator. Asian J Pharm Clin Res, Vol 11, Issue 7, 2018, 356- 359.
  23. Baby, A. R., Zague, V., Maciel, C.P.M., Kaneko, T. M., Consiglieri, V. O., Velasco and M. V. R, (2004). Development of Cosmetic Mask Formulations. Rev Bras Cienc. Farm
  24. Ahmed, S.A. and M. Grainage, 1985. Use of indigenous plant resources in rural development, potential of neem tree. Int. J. Dev. Technol., 3: 123-130
  25. Fallah, A., V.M. Ghalavand and R. Khajepour, 2006. Effects of blending method of livestock compost with soil and mixing it with chemical compost on yield and parts ofyield of seed corn in Khorramabad. Lorestan Agric. Nat. Resour. Sci. Magaz., 40: 233-242.
  26. Ashawat MS, Banchhor M. Herbal Cosmetics. Trends in skin care formulation.
  27. Singh H.P., Samnhotra N., Gullaiya S., Kaur I. Anti-acne synergistic Herbal face wash gel Formulation Evaluation, & Stability study, World Journal of Pharmaceutical Research, 2015;4(9): 1261-1273.

Reference

  1. Fatima Grace X, Anbarasan B, Kanimozhi T, Shanmuganathan S*. Preparation andEvaluation of Deep Cleansing Exfoliator. Asian J Pharm Clin Res 2018; Vol. 11, Issue 7.
  2. Aglawe SB*, Gayke AU, Khurde A, Mehta D, Mohare T, Pangavane A, Kandalkar
  3. S. Preparation and Evaluation of Polyherbal Facial Scrub. J Drug Delivery and Therapeutics.2019; 9[2]:61-63
  4. Charulata T. Nemade*, Nayana Baste. Formulation and Evaluation of a Herbal Facial Scrub. World J Pharm Res 2014; Vol. 3, Issue 3, 4367-4371.
  5. Mahajan S, Gayakwad D, Tiwari A, Darwhekar GN: Formulation and Evaluation of Herbo- Mineral Facial Scrub. Journal of Drug Delivery and Therapeutics 2020 May 15;10(3):195-7
  6. Carvalho Neto DP, Gonot-Schoupinsky XP, GonotSchoupinsky FN: Coffee as a Naturally Beneficial and Sustainable Ingredient in Personal Care Products: A Systematic Scoping Review of the Evidence.
  7. Farheen B, Mohammed I: Design and development of unani face pack for skin care. European J Pharm Med Red. 2016;3(2):627- 632.
  8. Ghode DS, Chatur VM, Ghode DP, Shaha N, Prajapati S, Thorave A: Formulation And Evaluation Of Facial Scrub Containing Sunflower Seeds And Other Natural Ingredients. - Research. 2019 Jun 20;8(9):1772-81.
  9. Himaja N. Ashok kumar A, Bhart kumar B: Preparation and Evaluation of Poly Herbal Fruit Face Mask. J Res Pharm Sci. 2015;2(11):07-13.
  10. Upadhyay G, Verma S, Parvez N, Sharma PK: Recent trends in transdermal drug delivery system-a review. Advances in biological research. 2014;3:131-380.
  11. Yamini. K and Onesimus. T. Preparation and Evaluation of Herbal Anti-Acne Gel. Int J Pharm Bio Sci 4.2 (2013): 956 – 960.
  12. Gupta Anil, Sharma P.C, Tilakratne B M K S and Verma Anil K. Studies on physiochemical characteristics and fatty acid composition of wild apricot (Prunus armeniaca Linn.) kernel oil. Indian Journal natural Products and Resources 3.3 (2012): 366-370
  13. Jody P. Ebanks, R. Randall Wickett and Raymond E. Boissy. Mechanisms Regulating Skin Pigmentation: The Rise and Fall of Complexion Coloration. International Journal of Molecular Sciences 10 (2009): 4066-4087.
  14. Aswal A, Kalra M, Rout A. Preparation and evaluation of polyherbal cosmetic cream.Asian Pac J Trop Med 2012; 5:83-88, 1-4
  15. Pandey Shivanand, Meshya Nilam, D.Viral, Herbs Play an Important Role in the Field of Cosmetics, International Journal of PharmTech Research, .2(1); 632-639:2010.
  16. Prashant L Kole, Hemant R Jadhav, Prasad Thakurdesai and Anantha Naik Nagappa, cosmeticspotential of herbal extracts, Indian Journal of Natural Products and Resources (IJNPR) [FormerlyNatural Product Radiance (NPR)], 4(4); 315-321, 2005.
  17. Rutuja Prashant nangare, trupti Ashok thange. Formulation and evalution of polyherbal facial scrub page no.1, International Journal of Research Publication and Reviews.
  18. J. Prathyusha, N. S. Yamani, G. Santhosh, A. Aravind, B. Naresh Formulation and Evaluation of Polyherbal Face Scrubber for Oily Skin in Gel Form International Journal of Pharmaceutical Sciences and Drug Research 2019; 11(4): 126-128.
  19. Larsson, S.C.; Bergkvist, L.; Näslund, I.; Rutegård, J.; Wolk, A. Vitamin A, retinol, and carotenoids and the risk of gastric cancer: a prospective cohort study. Am. J. Clin. Nutr., 85(2); 497–503, 2007.
  20. Plants Database.United States Department of Agriculture [online].Natural Resources Conservation Service. Available at:http://plants.usda.gov/java/namesearch.Accessed, 2006.
  21. Drugs act Commercial?s, “Manual on Drugs and Cosmetics” [online], Second Edition,Published by Commercial Law Publishers (India) Pvt. Ltd., 2004.
  22. Grace Fatima et al. Preparation and Evaluation of Deep Cleansing Exfoliator. Asian J Pharm Clin Res, Vol 11, Issue 7, 2018, 356- 359.
  23. Baby, A. R., Zague, V., Maciel, C.P.M., Kaneko, T. M., Consiglieri, V. O., Velasco and M. V. R, (2004). Development of Cosmetic Mask Formulations. Rev Bras Cienc. Farm
  24. Ahmed, S.A. and M. Grainage, 1985. Use of indigenous plant resources in rural development, potential of neem tree. Int. J. Dev. Technol., 3: 123-130
  25. Fallah, A., V.M. Ghalavand and R. Khajepour, 2006. Effects of blending method of livestock compost with soil and mixing it with chemical compost on yield and parts ofyield of seed corn in Khorramabad. Lorestan Agric. Nat. Resour. Sci. Magaz., 40: 233-242.
  26. Ashawat MS, Banchhor M. Herbal Cosmetics. Trends in skin care formulation.
  27. Singh H.P., Samnhotra N., Gullaiya S., Kaur I. Anti-acne synergistic Herbal face wash gel Formulation Evaluation, & Stability study, World Journal of Pharmaceutical Research, 2015;4(9): 1261-1273.

Photo
Kartikay Prakash
Corresponding author

Assistant Professor, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.

Photo
Polly Gupta
Co-author

Associate Professor, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.

Photo
Shashank Tiwari
Co-author

Director (Academic and Research), Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.

Photo
Trivid Shukla
Co-author

Student, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.

Photo
Preeti Yadav
Co-author

Student, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.

Polly Gupta, Shashank Tiwari, Kartikay Prakash, Trivid Shukla, Preeti Yadav , Formulation And Evaluation Of Face Scrub In Modern Pharmaceutics: An Herbal Formulation, Int. J. of Pharm. Sci., 2024, Vol 2, Issue 3, 579-588. https://doi.org/10.5281/zenodo.10953561

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